{"id":334,"date":"2015-11-16T11:04:07","date_gmt":"2015-11-16T16:04:07","guid":{"rendered":"https:\/\/med.virginia.edu\/pathology\/?page_id=334"},"modified":"2019-05-22T16:18:12","modified_gmt":"2019-05-22T20:18:12","slug":"chance-john-luckey-ph-dm-d","status":"publish","type":"page","link":"https:\/\/med.virginia.edu\/pathology\/contact\/chance-john-luckey-ph-dm-d\/","title":{"rendered":"Chance John Luckey, M.D., Ph.D."},"content":{"rendered":"<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-3667 size-medium alignnone\" src=\"https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2019\/05\/LuckeyChance-email-225x300.jpg\" alt=\"\" width=\"225\" height=\"300\" srcset=\"https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2019\/05\/LuckeyChance-email-225x300.jpg 225w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2019\/05\/LuckeyChance-email-113x150.jpg 113w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2019\/05\/LuckeyChance-email-150x200.jpg 150w, https:\/\/med.virginia.edu\/pathology\/wp-content\/uploads\/sites\/290\/2019\/05\/LuckeyChance-email.jpg 244w\" sizes=\"(max-width: 225px) 100vw, 225px\" \/><br \/>\nAssociate Medical Director<\/p>\n<h4>EDUCATION:<\/h4>\n<p><strong>Medical School:<\/strong> University of Virginia, 2001<br \/>\n<strong>Fellowship:<\/strong> Transfusion Medicine, Harvard Joint Program in Transfusion Medicine ( Brigham and Women&#8217;s Hospital\/Children&#8217;s Hospital of Boston\/Dana Farber Cancer Center\/ Massachusetts General Hospital\/ Beth Isreal Deconess Hospital) 2005<\/p>\n<h4>RESEARCH:<\/h4>\n<p>Cytokine signaling and transcriptional regulation of red blood cell alloimmunization; Cytokine and transcriptional regulation of immune memory.<\/p>\n<h4>CLINICAL:<\/h4>\n<p>Cellular therapies and bone marrow transplantation. Transfusion medicine\/ blood banking in both adult and pediatric settings<\/p>\n<h4>REFERENCES:<\/h4>\n<ul>\n<li>Farth KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RF, Shishkin AA, Hatan M, Carrasco-Alfonso M, Mayer D<strong>, Luckey, CJ<\/strong>, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE: Genetics and epigenetic fine mapping of causal autoimmune disease varients.\u00a0 Nature 2015, 518:337-343.\u00a0 <a href=\"http:\/\/www.ncbi.nih.gov\/pubmed\/25363779\"><strong>http:\/\/www.ncbi.nih.gov\/pubmed\/25363779<\/strong><\/a>.\u00a0 DOI: 10.1038\/nature13825.<\/li>\n<li>Lu Y, Loh YH, Li H, Cesana M, Ficarro SB, Parikh JR, Salomonis N, Toh CX, Andreadis ST, <strong>Luckey CJ,<\/strong> Collins JJ, Daley GQ, MArto JA:\u00a0 Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells.\u00a0 Cell Stem Cell 2014, 15:92-101. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24813856\"><strong>http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24813856<\/strong><\/a> <strong>.<\/strong> DOI:\u00a0 10.1016\/j.stem.2014.04.002.<\/li>\n<li>Babic AM, Jang S, Nicolov E, Voicu H, <strong>Luckey, CJ:<\/strong> Culture of mouse amniotic fluid-derived cells on irradiated STO feeders results in the generation of primitive endoderm cell lines capable of self-renewal in vitro.\u00a0 Cells Tissues Organs 2013.\u00a0 198:111-126. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24060676\"><strong>http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24060676<\/strong><\/a> <strong>.\u00a0<\/strong> DOI: 10.1159\/000353942.<\/li>\n<li><strong>Luckey CJ,<\/strong> Silverstein LE: A mouse model of hemolytic disease of the newborn.\u00a0 Blood 2014, 122:1334-1335.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23971354\"><strong>http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23971354<\/strong><\/a> <strong>.<\/strong>\u00a0 DOI:10.1182\/blood-2013-07-512715.<\/li>\n<li>Quillen K, <strong>Luckey CJ:\u00a0<\/strong> Blood and bombs: blood use after the Boston Marathon bombing of April 15, 2013.\u00a0 Transfusion 2014, 54:1202-1203.<strong>\u00a0<\/strong> <a href=\"http:\/\/www.ncbi.nlm.gov\/pubmed\/24724792\"><strong>http:\/\/www.ncbi<\/strong><\/a>.\u00a0 DOI: 10.1111\/trf.12642.<strong>.nlm.gov\/pubmed\/24724792<\/strong><\/li>\n<li>Zhou F, Lu Y, Ficarro SB, Adelmant G, Jiang W, <strong>Luckey CJ<\/strong>, Marto JA:\u00a0 GEnome-scale proteome quantification by DEEP SEQ mass spectrometry.\u00a0 Nat Commun 2013, 4:2171.\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23862870\"><strong>http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23862870<\/strong><\/a> <strong>.\u00a0<\/strong> DOI:\u00a010.1038\/ncomms3171.<\/li>\n<li>Koleva RI, Ficarro SB, Radomska HS, Carrasco-Alfonso M, Alberta JA, Webber\u00a0 JT, <strong>Luckey CJ<\/strong>, Marcucci G, Tenen DG, Marto JA:\u00a0 C\/EBPI+\/- and DEK coordinately regulate myeloid differentiation.\u00a0 Blood 2012, 119:4878-4888<strong>.\u00a0<\/strong> <a href=\"http:\/\/ncbi.nlm.nih.gov\/pubmed\/22474248\"><strong>http:\/\/ncbi.nlm.nih.gov\/pubmed\/22474248<\/strong><\/a> <strong>.<\/strong> DOI: 10.1182\/blood-201AHou F, Lu Y, FIcarro SB, Adelmant G, Jiang W, 1-10-383083.<\/li>\n<li><strong>Luckey CJ<\/strong>, Lu Y, Marto JA: Understanding the first steps in embryonic stem cell exit from the pluripotent state.\u00a0 Transfusion 2011, 51 Suppl 4:228S-124S.\u00a0 <a href=\"http:\/\/ncbi.nlm.nih.gov\/pubmed\/22074622\"><strong>http:\/\/ncbi.nlm.nih.gov\/pubmed\/22074622<\/strong><\/a> <strong>.<\/strong> DOI:\u00a0 10.111\/j.1537-2995.2011.03374.x.<\/li>\n<li>Zhang Y, ASkenazi M, Jiang J, <strong>Luckey CJ<\/strong>, Griffin JD, Marto JA: A robust error model for iTRAQ quantification reveals divergent signaling between oncogenic FLT3 mutants in acute myeloid leukemia.\u00a0 Mol Cell Proteomics 2010, 9:780-790.\u00a0 <a href=\"http:\/\/ncbi.nlm.nih.gov\/pubmed\/20019052\">h<strong>ttp:\/\/ncbi.nlm.nih.gov\/pubmed\/20019052<\/strong><\/a>.\u00a0 DOI:\u00a0 10.1074\/mcp.M900452-MCP200.<\/li>\n<li>Ficarro SB, Zhang Y, Lu Y, Moghimi AR, Askenazi M, Hyatt E, Smith ED, Boyer L, Schlaeger TM, <strong>Luckey CJ<\/strong>, Marto JA: Improved electrospray ionization efficiency compensates for diminished Chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells.\u00a0 Anal CHem 2009, 81:3440-3447.\u00a0 <a href=\"http:\/\/ncbi.nlm.nih.gov.pubmed\/19331382\"><strong>http:\/\/ncbi.nlm.nih.gov.pubmed\/19331382<\/strong><\/a> <strong>.<\/strong>\u00a0 DOI:\u00a0 10.1021\/ac802720e.<\/li>\n<li><strong>Luckey cj<\/strong>, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, Mathis D:\u00a0 Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells.\u00a0 Proc Nat&#8217;l Acad Aci I S A 2006, 103:3304-3309.\u00a0 <a href=\"http:\/\/ncbi.nlm.nih.gov.pubmed\/16492737\"><strong>http:\/\/ncbi.nlm.nih.gov.pubmed\/16492737<\/strong><\/a> <strong>.<\/strong>\u00a0 DOI: 10.1073\/pnas.0511137103.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Associate Medical Director EDUCATION: Medical School: University of Virginia, 2001 Fellowship: Transfusion Medicine, Harvard Joint Program in Transfusion Medicine ( Brigham and Women&#8217;s Hospital\/Children&#8217;s Hospital of Boston\/Dana Farber Cancer Center\/ Massachusetts General Hospital\/ Beth Isreal Deconess Hospital) 2005 RESEARCH: Cytokine signaling and transcriptional regulation of red blood cell alloimmunization; Cytokine and transcriptional regulation of immune [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":14,"menu_order":27,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"tags":[],"class_list":["post-334","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Chance John Luckey, M.D., Ph.D. - Department of Pathology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/pathology\/contact\/chance-john-luckey-ph-dm-d\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chance John Luckey, M.D., Ph.D. - Department of Pathology\" 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