The UVa Molecular Electron Microscopy Core laboratory is committed to transmission electron microscopy of samples larger than 250 KDa, with the goal of image reconstruction at better than 1nm resolution. The facility’s three electron microscopes provide a progression of capability, from the Tecnai Spirit for initial screening of negative-stained samples, to the Tecnai F20 for preliminary electron cryomicroscopy, to the advanced Titan Krios, which is dedicated to automated data collection for high-resolution analysis.
[Link to Molecular Electron Microscopy Core]
Core Director and Assistant Professor of Research in Molecular Biology and Biological Physics
Electron cryomicroscopy of proteins and macromolecular complexes.