{"id":2938,"date":"2022-06-27T10:35:09","date_gmt":"2022-06-27T14:35:09","guid":{"rendered":"https:\/\/med.virginia.edu\/physiology-biophysics\/?p=2938"},"modified":"2023-11-28T13:27:48","modified_gmt":"2023-11-28T18:27:48","slug":"congratulations-to-jochen-zimmer-and-his-lab-on-their-publication-in-nature","status":"publish","type":"post","link":"https:\/\/med.virginia.edu\/physiology-biophysics\/2022\/06\/27\/congratulations-to-jochen-zimmer-and-his-lab-on-their-publication-in-nature\/","title":{"rendered":"Congratulations to Jochen Zimmer and his lab on their publication in Nature"},"content":{"rendered":"

Congratulations to Jochen Zimmer and his lab on the publication of the structure and mechanism of substrate recognition of hyaluronan synthase in Nature<\/i> (https:\/\/www.nature.com\/articles\/s41586-022-04534-2<\/a>). Hyaluronan is a ubiquitous acidic glycosaminoglycan of the vertebrate extracellular matrix that is particularly enriched in connective tissues, the vasculature and the cartilage. It modulates a broad range of tissue remodeling processes, including wound healing, embryological development, angiogenesis and tumorigenesis. Determining how this integral membrane protein links hyaluronan biosynthesis to export across the cellular membrane represents a major milestone in our understanding of the development and regeneration after injury of vertebrates including humans from early embryos to adults.<\/p>\n","protected":false},"excerpt":{"rendered":"

Congratulations to Jochen Zimmer and his lab on the publication of the structure and mechanism of substrate recognition of hyaluronan synthase in Nature (https:\/\/www.nature.com\/articles\/s41586-022-04534-2). Hyaluronan is a ubiquitous acidic glycosaminoglycan of the vertebrate extracellular matrix that is particularly enriched in connective tissues, the vasculature and the cartilage. It modulates a broad range of tissue remodeling […]<\/p>\n","protected":false},"author":431,"featured_media":3382,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[1],"tags":[],"class_list":["post-2938","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"acf":false,"yoast_head":"\nCongratulations to Jochen Zimmer and his lab on their publication in Nature - Molecular Physiology and Biological Physics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/med.virginia.edu\/physiology-biophysics\/2022\/06\/27\/congratulations-to-jochen-zimmer-and-his-lab-on-their-publication-in-nature\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Congratulations to Jochen Zimmer and his lab on their publication in Nature - Molecular Physiology and Biological Physics\" \/>\n<meta property=\"og:description\" content=\"Congratulations to Jochen Zimmer and his lab on the publication of the structure and mechanism of substrate recognition of hyaluronan synthase in Nature (https:\/\/www.nature.com\/articles\/s41586-022-04534-2). 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