Kun Qing, PhD

Kun Qing, PhD

Assistant Professor of Radiology and Medical Imaging

BS, Biomedical Engineering, Tsinghua University, China,  2005
MS, Biomedical Engineering,Tsinghua University, China, 2007
PhD, Biomedical Engineering, University of Virginia, 2013

University of Virginia
Department of Radiology and Medical Imaging
Fontaine Research Park
480 Ray C. Hunt Dr.
Charlottesville, VA 22903

kq4d@virginia.edu

Research Interests

Dr. Qing is currently working on a new technology for MRI of the lungs. The results from this project will help obtain information on therapeutic responses to two major classes of current COPD medicines: long acting bronchodilators and inhaled steroids, and this information will improve our understanding of the functional responses of the lungs with COPD to the treatment. Secondly, this project is expected to provide evidence to consider magnetic resonance imaging technique using hyperpolarized zenon-129 gas as a diagnostic strategy to assess and monitor therapeutic responses of new and existing pharmaceuticals, and thus this technique will likely become a valuable tool in the development of novel disease-modifying therapies for COPD.

Research Lab

Xw129 MRI of the Lung: A New Technology to Assess Treatement for COPD
Simulatneous Xe129 MRI of Regional Lung Ventilation and Gas Uptake in COPD
Reginal Quantification of Lung Function in Cystic Fibrosis using Xe129 MRI

Publications

Atlas-based estimation of lung and lobar anatomy in proton MRI. Tustison NJ, Qing K, Wang C, Altes TA, Mugler JP 3rd. Magn Reson Med. 2016 Jul;76(1):315-20. doi: 10.1002/mrm.25824. Epub 2015 Jul 29. PMID: 26222827

Regional anisotropy of airspace orientation in the lung as assessed with hyperpolarized helium-3 diffusion MRI. Komlosi P, Altes TA, Qing K, Mooney KE, Miller GW, Mata JF, de Lange EE, Tobias WA, Cates GD, Brookeman JR, Mugler JP. J Magn Reson Imaging. 2015 Dec;42(6):1777-82. doi: 10.1002/jmri.24950. PMID: 26012720

Rapid acquisition of helium-3 and proton three-dimensional image sets of the human lung in a single breath-hold using compressed sensing. Qing K, Altes TA, Tustison NJ, Feng X, Chen X, Mata JF, Miller GW, de Lange EE, Tobias WA, Cates GD Jr, Brookeman JR, Mugler JP 3rd. Magn Reson Med. 2015 Oct;74(4):1110-5. doi: 10.1002/mrm.25499. Epub 2014 Oct 21. PMID: 25335080

Assessment of lung function in asthma and COPD using hyperpolarized 129Xe chemical shift saturation recovery spectroscopy and dissolved-phase MRI. Qing K, Mugler JP 3rd, Altes TA, Jiang Y, Mata JF, Miller GW, Ruset IC, Hersman FW, Ruppert K. NMR Biomed. 2014 Dec;27(12):1490-501. doi: 10.1002/nbm.3179. Epub 2014 Aug 22. PMID: 25146558

Regional mapping of gas uptake by blood and tissue in the human lung using hyperpolarized xenon-129 MRI. Qing K, Ruppert K, Jiang Y, Mata JF, Miller GW, Shim YM, Wang C, Ruset IC, Hersman FW, Altes TA, Mugler JP 3rd. J Magn Reson Imaging. 2014 Feb;39(2):346-59. doi: 10.1002/jmri.24181. Epub 2013 May 16. PMID: 23681559