Acute Care & Trauma Research

Basic and Translational Research

Acute Care & Trauma research houses the Yang Lab, which focuses on two main fields: Myocardial ischemia/reperfusion injury (IRI) and septic shock. We aim to define cellular and molecular mechanisms of myocardial IRI to identify novel therapeutic targets. We are currently exploring the role of DAMP molecules, especially HMGB1 and cell-free DNA in enhancing inflammatory responses during post-ischemic reperfusion injury.