Nick Dimitrios Tsihlis, PhD

Ascorbate elastomer-coated ePTFE grafts inhibit neointimal hyperplasia and enhance vascular healing
Bioactive Materials. 2026; 56: 726 - 742. DOI:10.1016/J.BIOACTMAT.2025.10.014.

Humanized Citrullinated Histone H3 Monoclonal Antibody Improves Respiratory Function and Attenuates Neutrophil-Mediated Inflammation in a Rodent Model of Smoke Inhalation Lung Injury
Journal of the American College of Surgeons. 2026; 242(1): 1 - 12. DOI:10.1097/XCS.0000000000001620.

Mitsugumin 53 protects against smoke inhalation lung injury via suppressing the proinflammatory response in a rat model
Free Radical Biology and Medicine. 2026; 248: 43 - 51. DOI:10.1016/J.FREERADBIOMED.2026.02.027.

Nitric Oxide-releasing Nanofibers Prevent Restenosis After Arterial Injury in a Renal Failure Model
Journal of Surgical Research. 2026; 325: 746 - 756. DOI:10.1016/J.JSS.2026.03.115.

Peptide amphiphile nanofibers: advanced drug delivery platforms for cardiovascular therapeutics
Expert Opinion on Drug Delivery. 2026; 23(5): 909 - 917. DOI:10.1080/17425247.2026.2631770.

Apolipoprotein E Deficiency Produces an Inflammatory Abdominal Aortic Aneurysm in a Rat Calcium Chloride-Induced Model
Journal of Surgical Research. 2025; 312: 83 - 93. DOI:10.1016/J.JSS.2025.05.011.

A Targeted Nanofiber Loaded With Liver X Receptor Agonist Reduces Atherosclerotic Plaque and Prevents Hepatotoxicity
JVS: Vascular Science. 2023; 4: 100152. DOI:10.1016/J.JVSSCI.2023.100152.

Abstract 127: A Targeted Nanofiber Loaded With Liver X Receptor Agonist Reduces Atherosclerotic Plaque And Prevents Hepatotoxicity
Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43(Suppl_1):. DOI:10.1161/ATVB.43.SUPPL_1.127.

Effects of Particle Size, Charge, Shape, Animal Disease State, and Sex on the Biodistribution of Intravenously Administered Nanoparticles
Particle and Particle Systems Characterization. 2023; 40(7):. DOI:10.1002/PPSC.202300001.

Systemic peptide amphiphile nanofiber delivery following subcutaneous injection
Biomaterials. 2023; 303: 122401. DOI:10.1016/J.BIOMATERIALS.2023.122401.

Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms
ACS Nano. 2022; 16(5): 7309 - 7322. DOI:10.1021/ACSNANO.1C06258.

Coating small-diameter ePTFE vascular grafts with tunable poly(diol- co -citrate- co -ascorbate) elastomers to reduce neointimal hyperplasia
Biomaterials Science. 2021; 9(15): 5160 - 5174. DOI:10.1039/D1BM00101A.

Development of Novel Nanofibers Targeted to Smoke-Injured Lungs
Biomaterials. 2021; 274: 120862. DOI:10.1016/J.BIOMATERIALS.2021.120862.

Emerging antenatal therapies for congenital diaphragmatic hernia-induced pulmonary hypertension in preclinical models
Pediatric Research. 2021; 89(7): 1641 - 1649. DOI:10.1038/S41390-020-01191-X.

Evaluation of a Targeted Drug‐Eluting Intravascular Nanotherapy to Prevent Neointimal Hyperplasia in an Atherosclerotic Rat Model
Advanced NanoBiomed Research. 2021; 1(7):. DOI:10.1002/ANBR.202000093.

Intravenous Delivery of Lung‐Targeted Nanofibers for Pulmonary Hypertension in Mice
Advanced Healthcare Materials. 2021; 10(13):. DOI:10.1002/ADHM.202100302.

Self‐Assembled Peptide Amphiphile Nanofibers for Controlled Therapeutic Delivery to the Atherosclerotic Niche
Advanced Therapeutics. 2021; 4(9):. DOI:10.1002/ADTP.202100103.

Targeted Delivery of a Nanotherapeutic to Prevent Arterial Restenosis in a Diabetic Environment
Journal of the American College of Surgeons. 2021; 233(5): S316 - S317. DOI:10.1016/J.JAMCOLLSURG.2021.07.656.

A comparative study of a preclinical survival model of smoke inhalation injury in mice and rats
American Journal of Physiology - Lung Cellular and Molecular Physiology. 2020; 319(3): L471 - L480. DOI:10.1152/AJPLUNG.00241.2020.

Development of Fractalkine-Targeted Nanofibers that Localize to Sites of Arterial Injury
Nanomaterials. 2020; 10(3): 420. DOI:10.3390/NANO10030420.

Development of Optimized Tissue-Factor-Targeted Peptide Amphiphile Nanofibers to Slow Noncompressible Torso Hemorrhage
ACS Nano. 2020; 14(6): 6649 - 6662. DOI:10.1021/ACSNANO.9B09243.

Development of Poly(1,8-octanediol- co -citrate- co -ascorbate) Elastomers with Enhanced Ascorbate Performance for Use as a Graft Coating to Prevent Neointimal Hyperplasia
ACS Applied Bio Materials. 2020; 3(4): 2150 - 2159. DOI:10.1021/ACSABM.0C00019.

Emerging Therapies for Prehospital Control of Hemorrhage
Journal of Surgical Research. 2020; 248: 182 - 190. DOI:10.1016/J.JSS.2019.09.070.

Emerging therapies for smoke inhalation injury: a review
Journal of Translational Medicine. 2020; 18(1):. DOI:10.1186/S12967-020-02300-4.

Pharmacokinetics and biodistribution of a collagen‐targeted peptide amphiphile for cardiovascular applications
Pharmacology Research & Perspectives. 2020; 8(6):. DOI:10.1002/PRP2.672.

Atheroma Niche‐Responsive Nanocarriers for Immunotherapeutic Delivery
Advanced Healthcare Materials. 2019; 8(3):. DOI:10.1002/ADHM.201801545.

Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis
Macromolecular Bioscience. 2019; 19(6):. DOI:10.1002/MABI.201900066.

Peptide Amphiphile Supramolecular Nanostructures as a Targeted Therapy for Atherosclerosis
Macromolecular Bioscience. 2019; 19(6):. DOI:10.1002/MABI.201970016.

Correctionto Tissue-Factor Targeted Peptide Amphiphile Nanofibers as an InjectableTherapy To Control Hemorrhage
ACS Nano. 2018; 12(11): 11711 - 11711. DOI:10.1021/ACSNANO.8B07028.

Systemic Delivery of a Novel Fractalkine Binding Peptide Amphiphile Nanofiber to Target Injured Vasculature
Journal of the American College of Surgeons. 2018; 227(4): S296 - S297. DOI:10.1016/J.JAMCOLLSURG.2018.07.615.

Nitric oxide differentially affects proteasome activator 28 after arterial injury in type 1 and type 2 diabetic rats
Journal of Surgical Research. 2016; 202(2): 413 - 421. DOI:10.1016/J.JSS.2016.01.030.

Tissue-Factor Targeted Peptide Amphiphile Nanofibers as an Injectable Therapy To Control Hemorrhage
ACS Nano. 2016; 10(1): 899 - 909. DOI:10.1021/ACSNANO.5B06025.