Maurits A. Jansen

Lois Q Balugo JL, Samuels JD, Milstein JL, Jansen MA, Harris TE, Culver SA. Quantifying renal lipid accumulation in obese murine models using Magnetic
Resonance Imaging (MRI). Biochem Biophys Res Commun. 2025 May 5;762:151765. doi:10.1016/j.bbrc.2025.151765.2022

2024

Munro, D. A. D., Bestard-Cuche, N., McQuaid, C., Chagnot, A., Shabestari, S. K., Chadarevian, J. P., . . . Priller, J. (2024). Microglia protect against age-associated brain pathologies.. Neuron, S0896-6273(24)00365-9. doi:10.1016/j.neuron.2024.05.018

2022

Kaczynski, J., Sellers, S., Seidman, M. A., Syed, M., Dennis, M., Mcnaught, G., . . . Williams, M. C. (2022). ¹⁸F-NaF PET/MRI for Detection of Carotid Atheroma in Acute Neurovascular Syndrome. RADIOLOGY, 305(1), 137-148. doi:10.1148/radiol.212283

Naredo-Gonzalez, G., Upreti, R., Jansen, M. A., Semple, S., Sutcliffe, O. B., Marshall, I., . . . Andrew, R. (2022). Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by ¹⁹F-Magnetic Resonance Spectroscopy. SCIENTIFIC REPORTS, 12(1). doi:10.1038/s41598-022-18740-5

Quick, S., Procter, T. V., Moss, J., Seeker, L., Walton, M., Lawson, A., . . . Williams, A. (2022). Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model. ACTA NEUROPATHOLOGICA, 144(2), 283-303. doi:10.1007/s00401-022-02441-4

Hallett, J. M., Ferreira-Gonzalez, S., Man, T. Y., Kilpatrick, A. M., Esser, H., Thirlwell, K., . . . Forbes, S. J. (2022). Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease. CELL STEM CELL, 29(3), 355-+. doi:10.1016/j.stem.2022.02.006

Bonneau, M., Sullivan, S. T. O., Gonzalez-Lozano, M. A., Baxter, P., Gautier, P., Marchisella, E., . . . Kirsty Millar, J. (2021). Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness. TRANSLATIONAL PSYCHIATRY, 11(1). doi:10.1038/s41398-021-01256-3

Prokopiou, E. D., Pissas, M., Fibbi, G., Margheri, F., Kalska-Szostko, B., Papanastasiou, G., . . . Efthimiadou, K. E. (2021). Synthesis and characterization of modified magnetic nanoparticles as theranostic agents: in vitro safety assessment in healthy cells. TOXICOLOGY IN VITRO, 72. doi:10.1016/j.tiv.2021.105094

Li, M., Kitamura, A., Beverley, J., Koudelka, J., Duncombe, J., Lennen, R., . . . Horsburgh, K. (2022). Impaired Glymphatic Function and Pulsation Alterations in a Mouse Model of Vascular Cognitive Impairment. FRONTIERS IN AGING NEUROSCIENCE, 13. doi:10.3389/fnagi.2021.788519

Stringer, M. S., Lee, H., Huuskonen, M. T., MacIntosh, B. J., Brown, R., Montagne, A., . . . Wardlaw, J. M. (2021). A Review of Translational Magnetic Resonance Imaging in Human and Rodent Experimental Models of Small Vessel Disease. TRANSLATIONAL STROKE RESEARCH, 12(1), 15-30. doi:10.1007/s12975-020-00843-8

Kuhn, J., Papanastasiou, G., Tai, C. -W., Moran, C. M., Jansen, M. A., Tavares, A. A. S., . . . Yiu, H. H. P. (2020). Tri-modal imaging of gold-dotted magnetic nanoparticles for magnetic resonance imaging, computed tomography and intravascular ultrasound: an in vitro study. NANOMEDICINE, 15(25). doi:10.2217/nnm-2020-0236

Kwiecinski, J., Lennen, R. J., Gray, G. A., Borthwick, G., Boswell, L., Baker, A. H., . . . Jansen, M. A. (2020). Progression and regression of left ventricular hypertrophy and myocardial fibrosis in a mouse model of hypertension and concomitant cardiomyopathy. JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, 22(1). doi:10.1186/s12968-020-00655-7

Spath, N., Tavares, A., Gray, G. A., Baker, A. H., Lennen, R. J., Alcaide-Corral, C. J., . . . Semple, S. I. (2020). Manganese-enhanced T₁ mapping to quantify myocardial viability: validation with ¹⁸F-fluorodeoxyglucose positron emission tomography. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-58716-x

Kwiecinski, J., Dey, D., Cadet, S., Lee, S. -E., Otaki, Y., Huynh, P. T., . . . Berman, D. S. (2019). Peri-Coronary Adipose Tissue Density Is Associated With ¹⁸F-Sodium Fluoride Coronary Uptake in Stable Patients With High-Risk Plaques. JACC-CARDIOVASCULAR IMAGING, 12(10), 2000-2010. doi:10.1016/j.jcmg.2018.11.032

Kwiecinski, J., Adamson, P. D., Lassen, M. L., Doris, M. K., Moss, A. J., Cadet, S., . . . Slomka, P. J. (2018). Feasibility of Coronary ¹⁸F-Sodium Fluoride Positron-Emission Tomography Assessment With the Utilization of Previously Acquired Computed Tomography Angiography. CIRCULATION-CARDIOVASCULAR IMAGING, 11(12). doi:10.1161/CIRCIMAGING.118.008325

Kwiecinski, J., Berman, D. S., Lee, S. -E., Dey, D., Cadet, S., Lassen, M. L., . . . Slomka, P. J. (2019). Three-Hour Delayed Imaging Improves Assessment of Coronary ¹⁸F-Sodium Fluoride PET. JOURNAL OF NUCLEAR MEDICINE, 60(4), 530-535. doi:10.2967/jnumed.118.217885

Humphreys, C. A., Jansen, M. A., Maniega, S. M., Gonzalez-Castro, V., Pernet, C., Deary, I. J., . . . Smith, C. (2019). A protocol for precise comparisons of small vessel disease lesions between ex vivo magnetic resonance imaging and histopathology. INTERNATIONAL JOURNAL OF STROKE, 14(3), 310-320. doi:10.1177/1747493018799962

McMaster, M. E., Ashley-Sing, C., Tavares, A. A. D. S., Corral, C. A., McGill, K., McNeil, D., . . . Simpson, A. H. R. W. (2018). The inhalation effects of by-products from chlorination of heated indoor swimming pools on spinal development in pup mice. ENVIRONMENTAL RESEARCH, 166, 668-676. doi:10.1016/j.envres.2018.06.049

Hoy, A. M., McDonald, N., Lennen, R. J., Milanesi, M., Herlihy, A. H., Kendall, T. J., . . . Fallowfield, J. A. (2018). Non-invasive assessment of liver disease in rats using multiparametric magnetic resonance imaging: a feasibility study. BIOLOGY OPEN, 7(7). doi:10.1242/bio.033910

MacAskill, M. G., Saif, J., Condie, A., Jansen, M. A., MacGillivray, T. J., Tavares, A. A. S., . . . Baker, A. H. (2018). Robust Revascularization in Models of Limb Ischemia Using a Clinically Translatable Human Stem Cell-Derived Endothelial Cell Product. MOLECULAR THERAPY, 26(7), 1669-1684. doi:10.1016/j.ymthe.2018.03.017

Spath, N. B., Lilburn, D. M. L., Gray, G. A., Le Page, L. M., Papanastasiou, G., Lennen, R. J., . . . Semple, S. I. (2018). Manganese-Enhanced T₁ Mapping in the Myocardium of Normal and Infarcted Hearts. CONTRAST MEDIA & MOLECULAR IMAGING. doi:10.1155/2018/9641527

Kwiecinski, J., Dey, D., Lee, S. E., Otaki, Y., Doris, M. K., Eisenberg, E., . . . Berman, D. S. (2018). Pericoronary adipose tissue density and low attenuation plaque are associated with 18F-sodium fluoride coronary uptake in vulnerable plaque patients. In EUROPEAN HEART JOURNAL Vol. 39 (pp. 1285-1286).

Kitamura, A., Manso, Y., Duncombe, J., Searcy, J., Koudelka, J., Binnie, M., . . . Horsburgh, K. (2017). Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-04082-0

Kwiecinski, J., Chin, C. L., Everett, R. J., White, A. C., Semple, S., Yeung, E., . . . Dweck, M. R. (2018). Adverse prognosis associated with asymmetric myocardial thickening in aortic stenosis. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 19(3), 347-356. doi:10.1093/ehjci/jex052

Duncombe, J., Lennen, R. J., Jansen, M. A., Marshall, I., Wardlaw, J. M., & Horsburgh, K. (2017). Ageing causes prominent neurovascular dysfunction associated with loss of astrocytic contacts and gliosis. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 43(6), 477-491. doi:10.1111/nan.12375

Sharkey, J., Lewis, P. J. S., Barrow, M., Alwahsh, S. M., Noble, J., Livingstone, E., . . . Park, B. K. (2017). Functionalized superparamagnetic iron oxide nanoparticles provide highly efficient iron-labeling in macrophages for magnetic resonance-based detection in vivo. CYTOTHERAPY, 19(4), 555-569. doi:10.1016/j.jcyt.2017.01.003

Snowdon, V. K., Lachlan, N. J., Hoy, A. M., Hadoke, P. W. F., Semple, S. I., Patel, D., . . . Fallowfield, J. A. (2017). Serelaxin as a potential treatment for renal dysfunction in cirrhosis: Preclinical evaluation and results of a randomized phase 2 trial. PLOS MEDICINE, 14(2). doi:10.1371/journal.pmed.1002248

Jansen, M. A., Cornateanu, S. M., Lennen, R. J., & Oniscu, G. C. (2017). DEVELOPMENT OF AN MRI SCORE TO ASSESS THE QUALITY OF PANCREAS GRAFTS PRIOR TO TRANSPLANTATION. In TRANSPLANT INTERNATIONAL Vol. 30 (pp. 21-22).

Merrifield, G. D., Mullin, J., Gallagher, L., Tucker, C., Jansen, M. A., Denvir, M., & Holmes, W. M. (2017). Rapid and recoverable in vivo magnetic resonance imaging of the adult zebrafish at 7T. MAGNETIC RESONANCE IMAGING, 37, 9-15. doi:10.1016/j.mri.2016.10.013

Mahmoud, A. D., Lewis, S., Juricic, L., Udoh, U. -A., Hartmann, S., Jansen, M. A., . . . Evans, A. M. (2016). AMP-activated Protein Kinase Deficiency Blocks the Hypoxic Ventilatory Response and Thus Precipitates Hypoventilation and Apnea. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 193(9), 1032-1043. doi:10.1164/rccm.201508-1667OC

Harris, A. P., Lennen, R. J., Brydges, N. M., Jansen, M. A., Pernet, C. R., Whalley, H. C., . . . Hall, J. (2016). The role of brain-derived neurotrophic factor in learned fear processing: an awake rat fMRI study. GENES BRAIN AND BEHAVIOR, 15(2), 221-230. doi:10.1111/gbb.12277

Milidonis, X., Lennen, R. J., Jansen, M. A., Mueller, S., Boehm-Sturm, P., Holmes, W. M., . . . Marshall, I. (2016). Multicenter Evaluation of Geometric Accuracy of MRI Protocols Used in Experimental Stroke. PLOS ONE, 11(9). doi:10.1371/journal.pone.0162545

White, C. I., Jansen, M. A., McGregor, K., Mylonas, K. J., Richardson, R. V., Thomson, A., . . . Gray, G. A. (2016). Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice. ENDOCRINOLOGY, 157(1), 346-357. doi:10.1210/en.2015-1630

Zhao, X., Wu, J., Gray, C. D., McGregor, K., Rossi, A. G., Morrison, H., . . . Gray, G. A. (2015). Optical projection tomography permits efficient assessment of infarct volume in the murine heart postmyocardial infarction. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 309(4), H702-H710. doi:10.1152/ajpheart.00233.2015

Harris, A. P., Lennen, R. J., Marshall, I., Jansen, M. A., Pernet, C. R., Brydges, N. M., . . . Holmes, M. C. (2015). Imaging learned fear circuitry in awake mice using fMRI. EUROPEAN JOURNAL OF NEUROSCIENCE, 42(5), 2125-2134. doi:10.1111/ejn.12939

Alam, S. R., Tse, G. H., Stirrat, C., MacGillivray, T. J., Lennen, R. J., Jansen, M. A., . . . Henriksen, P. A. (2015). Nanoparticle enhanced MRI scanning to detect cellular inflammation in experimental chronic renal allograft rejection.. International journal of molecular imaging, 2015, 507909. doi:10.1155/2015/507909

Merrifield, G., Mullin, J., Gallagher, L., Tucker, C., Jansen, M., Holmes, W., & Denvir, M. (2015). IN VIVO CARDIAC MAGNETIC RESONANCE IMAGING OF ADULT ZEBRAFISH. In HEART Vol. 101 (pp. A96-A97). doi:10.1136/heartjnl-2015-308066.170

Merrifield, G. D., Mullin, J., Gallagher, L., Tucker, C., Jansen, M. A., Denvir, M., & Holmes, W. M. (2015). DEVELOPING CARDIAC MAGNETIC RESONANCE IMAGING IN THE LIVE ZEBRAFISH. In HEART Vol. 101 (pp. A6). doi:10.1136/heartjnl-2015-308734.16

Holland, P. R., Pannozzo, M. A., Bastin, M. E., McNeilly, A. D., Ferguson, K. J., Caughey, S., . . . Horsburgh, K. (2015). Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 35(2), 188-192. doi:10.1038/jcbfm.2014.201

Girardi, G., Fraser, J., Lennen, R., Vontell, R., Jansen, M., & Hutchison, G. (2015). Imaging of activated complement using ultrasmall superparamagnetic iron oxide particles (USPIO) - conjugated vectors: an in vivo in utero non-invasive method to predict placental insufficiency and abnormal fetal brain development. MOLECULAR PSYCHIATRY, 20(8), 1017-1026. doi:10.1038/mp.2014.110

Stirrat, C. G., Newby, D. E., Robson, J. M. J., & Jansen, M. A. (2014). The Use of Superparamagnetic Iron Oxide Nanoparticles to Assess Cardiac Inflammation. CURRENT CARDIOVASCULAR IMAGING REPORTS, 7(5). doi:10.1007/s12410-014-9263-3

Pedroni, S. M. A., Gonzalez, J. M., Wade, J., Jansen, M. A., Serio, A., Marshall, I., . . . Girardi, G. (2014). Complement inhibition and statins prevent fetal brain cortical abnormalities in a mouse model of preterm birth. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1842(1), 107-115. doi:10.1016/j.bbadis.2013.10.011

Menzies, R. I., Zammit-Mangion, A., Hollis, L. M., Lennen, R. J., Jansen, M. A., Webb, D. J., . . . Bailey, M. A. (2013). An anatomically unbiased approach for analysis of renal BOLD magnetic resonance images. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 305(6), F845-F852. doi:10.1152/ajprenal.00113.2013

Marshall, I., Jansen, M. A., Tao, Y., Merrifield, G. D., & Gray, G. A. (2014). Application of kt-BLAST acceleration to reduce cardiac MR imaging time in healthy and infarcted mice. MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE, 27(3), 201-210. doi:10.1007/s10334-013-0392-5

Brydges, N. M., Whalley, H. C., Jansen, M. A., Merrifield, G. D., Wood, E. R., Lawrie, S. M., . . . Holmes, M. C. (2013). Imaging Conditioned Fear Circuitry Using Awake Rodent fMRI. PLOS ONE, 8(1). doi:10.1371/journal.pone.0054197

Gray, G. A., White, C. I., Thomson, A., Kozak, A., Moran, C., & Jansen, M. A. (2013). Imaging the healing murine myocardial infarct in vivo: ultrasound, magnetic resonance imaging and fluorescence molecular tomography. EXPERIMENTAL PHYSIOLOGY, 98(3), 606-613. doi:10.1113/expphysiol.2012.064741

Fortune, S., Jansen, M. A., Anderson, T., Gray, G. A., Schneider, J. E., Hoskins, P. R., & Marshall, I. (2012). Development and characterization of rodent cardiac phantoms: comparison with in vivo cardiac imaging. MAGNETIC RESONANCE IMAGING, 30(8), 1186-1191. doi:10.1016/j.mri.2012.04.008

Evans, L. C., Livingstone, D. E., Kenyon, C. J., Jansen, M. A., Dear, J. W., Mullins, J. J., & Bailey, M. A. (2012). A urine-concentrating defect in 11β-hydroxysteroid dehydrogenase type 2 null mice. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 303(4), F494-F502. doi:10.1152/ajprenal.00165.2012

Thrippleton, M. J., Bastin, M. E., Munro, K. I., Williams, A. R., Oniscu, A., Jansen, M. A., . . . Critchley, H. O. (2011). Ex Vivo Water Diffusion Tensor Properties of the Fibroid Uterus at 7 T and Their Relation to Tissue Morphology. JOURNAL OF MAGNETIC RESONANCE IMAGING, 34(6), 1445-1451. doi:10.1002/jmri.22793

Dhaliwal, K., Alexander, L., Escher, G., Unciti-Broceta, A., Jansen, M., Mcdonald, N., . . . Bradley, M. (2011). Multi-modal molecular imaging approaches to detect primary cells in preclinical models. FARADAY DISCUSSIONS, 149, 107-114. doi:10.1039/c005410k

Holland, P. R., Bastin, M. E., Jansen, M. A., Merrifield, G. D., Coltman, R. B., Scott, F., . . . Horsburgh, K. (2011). MRI is a sensitive marker of subtle white matter pathology in hypoperfused mice. NEUROBIOLOGY OF AGING, 32(12). doi:10.1016/j.neurobiolaging.2010.11.009

Jackson, S. J., Hussey, R., Jansen, M. A., Merrifield, G. D., Marshall, I., MacLullich, A., . . . Bast, T. (2011). Manganese-enhanced magnetic resonance imaging (MEMRI) of rat brain after systemic administration of MnCl₂: Hippocampal signal enhancement without disruption of hippocampus-dependent behavior. BEHAVIOURAL BRAIN RESEARCH, 216(1), 293-300. doi:10.1016/j.bbr.2010.08.007