Faculty

Computational Biology; Bioinformatics; Precision Medicine; Machine Learning/AI; Quantum Computing

Genome instability syndromes in cancer and immune deficiencies

Structure and Function of Macromolecular Complexes Using Electron Microscopy

Acute Myeloid Leukemia: molecular and cellular biology events which mediate aberrant epigenetic and transcriptional mechanisms during disease establishment and progression

Metabolic and Genetic Regulation of Aging, Redox Biology, DNA Repair, Comparative and Functional Genomics, Stress Resistance, Drug Discovery, Evolutionary Biology, Synthetic and Systems Biology for Evolutionary Engineering, Adaptive Evolution, Mitochondrial Signaling, Neurodegenerative Diseases

Molecular and metabolic adaptations of cancer cells.

Transcriptional Regulation by NFKB

Cell signaling, stem cell biology, molecular and epigenetic mechanisms of blood and breast cancers

Nuclear Transport, Signaling, and Cancer

Transcriptional Silencing and Aging in Yeast

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Complex Genome Rearrangements

Genome instability in cancer and repeat expansion diseases

Mechanisms of DNA repair in chromatin

Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling

Structural biology, Cryo-EM, Mitochondrial stress, Integrated stress response, De novo protein design, Drug development, Neurodegeneration, Heart disease, Cancer

Integrating high-throughput proteomic, chemical, genetic and computational tools for target identification and drug discovery in cancer biology

The Ubiquitin System and Human Cancer

Pediatric Medicine, Pediatric Hematology and Oncology, Pediatric Cancer

Systems Genetics of Skeletal Development and Maintenance

Hematology & Oncology

Systems-biology approaches to cancer biology and virology.

Gene regulation in cancer, RNA processing; Epigenetic modification; Stem cell and development

Genetic and Epigenetic stability in human cancer

Chemical biology of sphingosine 1-phosphate

Statistical Genetics, Genetic Epidemiology, Biostatistics, Network analysis

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Systems biology, infectious disease, cancer, toxicology, metabolic engineering

Novel therapeutic approaches to brain cancers and to other neurologic diseases

Genomics, Molecular Evolution, Algorithm Design and Analysis

Genetic basis of common human disease, including type 1 diabetes, diabetic complications, ischemic stroke, atherosclerosis

computational biology & bioinformatics; high performance computing; epigenomics & chromatin; pediatric cancer; computational regulatory genomics; machine learning

Proteoform Systems Biology: proteogenomic approaches to uncover the role of proteomic variation in human disease

Molecular and genetic determinants of atherosclerosis and cardiometabolic disorders.

Auditory Neurobiology

Clonal hematopoiesis: A new mechanism of cardiovascular disease

Bioinformatics methodology development; Epigenetics and chromatin biology; Transcriptional regulation; Cancer genomics and epigenomics; Statistical methods for biomedical data integration; Advanced machine learning; Theoretical and computational biophysics

MD-RONC Radiation Oncology