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BIG Faculty

Tajie Harris, Ph.D. (BIG Director)

Immune response to infectious disease in the CNS

Stuart Berr, Ph.D.

Medical and Molecular Imaging and Cardiovascular Engineering

George Bloom, Ph.D

Pathogenic mechanisms in Alzheimer’s Disease and other neurodegenerative disorders

Ashley Brandebura, Ph.D.

Astrocytes in neurodevelopmental and neurodegenerative disorders

Anna Cliffe, Ph.D.

Herpes Simplex Virus infection of neurons

Elise Cope, Ph.D.

Perineuronal Nets and Microglia in Hippocampal Plasticity

Jaeda Coutinho-Budd, Ph.D.

Neuron-glia and glial-glial interactions

Christopher Deppmann, Ph.D.

Mechanisms governing nervous system assembly and disassembly

Bimal Desai, Ph.D.

Ion channels and Ca2+-signaling in inflammation, immunity, and tissue homeostasis

Ukpong Eyo, Ph.D.

Microglia in neurodevelopment and neurodevelopmental disorders

Sarah Ewald, Ph.D.

Innate immunity, chronic disease, host-parasite interactions, Toxoplasma gondii, and proteomics

Heather Ferris, M.D., Ph.D.

The role of diabetes in cognitive decline

Sarah Flowers, Ph.D.

Targeting APOE for the diagnosis and treatment of the metabolic deficits of early Alzheimer’s disease

Alban Gaultier, Ph.D

Exploring new therapeutic avenues to treat Multiple Sclerosis.

Young Hahn, Ph.D

Immune regulation for HCV infection and chronic liver inflammation

Lulu Jiang, M.D., Ph.D.

Pathophysiology of neurodegenerative diseases

Chia-Yi (Alex) Kuan, M.D., Ph.D.

Neuro-Immune Interactions

Sarah Kucenas, Ph.D.

The role of glia in the development, maintenance, and regeneration of the nervous system

Kyle Lampe, Ph.D.

Neural tissue engineering, biomaterials, drug delivery, redox regulation of stem cell fate, engineering cell-interactive micro-environments

Kevin Lee, Ph.D.

Neuronal Vulnerability: A Study of Cellular Mechanism

Tsai-Yi Lu, Ph.D.

Oligodendrocyte lineage homeostasis

John Lukens, Ph.D.

Understanding How Immunological Pathways Contribute to Neurodegenerative, Neurodevelopmental, Mental and Behavior Disorders

James Mandell, M.D., Ph.D.

Identification of Novel Biomarkers for Inflammatory Myopathies

Shayn Peirce-Cottler, Ph.D.

Tissue Engineering and Regeneration, Computational Systems Biology, Vascular Growth and Remodeling, Stem Cell Therapies

William Petri, M.D., Ph.D.

Immune mechanisms of defense against COVID-19 and enteric (diarrheal) infections

Rebecca Pompano, Ph.D.

Bioanalytical tools for inflammatory disease

Richard Price, Ph.D.

Image Guided Drug and Gene Delivery for Neurodegeneration and Cancer; Focused Ultrasound and Immunotherapy; Arteriogenesis and Angiogenesis

Javier Provencio, M.D.

Innate Inflammatory Pathways Associated with Acute Aneurysmal Subarachnoid Hemorrhage

Benjamin Purow, M.D.

Novel therapeutic approaches to brain cancers and to other neurologic diseases

James Ross, Ph.D.

Brain tumor immunology

Harald Sontheimer, Ph.D.

Role of Glia in Neurological Illnesses and Cancer

Joshua Wythe, Ph.D.

Cardiovascular Development and Cerebrovascular Pathologies

Hui Zong, Ph.D.

Early detection, cancer prevention, and tumor microenvironment