Elise Cope, Ph.D.


Elise Cope, Ph.D., Neuroscience Faculty, UVAAssistant Professor

B.S., 2008, Florida State University

Ph.D., 2013, Florida State University

Postdoc, 2014-2021, Princeton University

Cope Lab Website



Research Interests

Perineuronal Nets and Microglia in Hippocampal Plasticity

Research Description

What are the mechanisms by which neuronal and nonneuronal forms of structural plasticity contribute to social memory in the healthy and diseased brain? To answer this question, my lab uses a variety of pharmacologic, transgenic, viral, and environmental manipulations combined with histology, in vivo electrophysiology, and behavioral analyses. We focus on the hippocampus, a brain region that not only plays an important role in social memory, but also undergoes substantial plasticity into adulthood. Ongoing projects explore adult-born granule cells, glia, and perineuronal nets in mediating hippocampal plasticity and social memory with the ultimate goal of our work to understand the impact of the collective interactions of these cells and extracellular structures.