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Cell Biology

Biomedical Sciences Graduate Program

About

Cell Biology Study Session on big tv screen

The Cell Biology program provides outstanding training of PhD candidates in a vibrant and rapidly evolving field.  Our comprehensive program emphasizes original research, interdisciplinary coursework, and advanced topical colloquia. Trainees have the opportunity to explore fundamental questions in many areas including molecular mechanisms of cell function; regulation of growth and differentiation; cell interactions in migration; embryonic patterning in development; and morphogenesis of cells, tissues and organs. Training in cell and developmental biology forms the basis not only for making fundamental new discoveries, but also for understanding and exploring the links to human diseases where the fundamental processes of cytoskeletal dynamics, membrane trafficking, signal transduction, mitosis, cell adhesion, motility, mechanotransduction, and polarity go awry. For more information, click here…

Program Faculty

Molecular Biosensors; Spatiotemporal Regulation of Biological Signaling; Protein Engineering for Imaging, Diagnostics, and Therapeutics

Systems biology approaches to study gene dosage in neurodevelopment and neurodevelopmental disorders

1. Molecular and cellular therapy for tissue injury and repair, mainly focusing on heart and lung injury and repair. 2. Cancer biology, mainly focusing on identifying the molecular target that can inhibit the tumorigenesis during aging.

Hematology and Oncology, Cell Biology, Lipid Signaling, Cancer Cell Signaling, and RNA Biology

Adult-born neurons, perineuronal nets, and microglia in hippocampal plasticity and behavior in health and disease

Neuron-glia and glial-glial interactions

Cell Adhesion and Adhesion-Dependent Cell Signaling in Vertebrate Morphogenesis

Neural Development; Cell Division in Neural Stem Cells; Axon Outgrowth and Guidance

Cytoskeletal architecture, dynamics and roles in cellular physiology and disease; High-resolution live cell and tissue imaging

Regeneration and Systemic Responses to Tissue Damage

Understanding Cellular and Molecular Mechanisms Leading to Blood Vessel Formation

The Role of Mitochondrial Fusion and Fission in Tumorigenesis.

Cellular and molecular mechanisms of morphogenesis

Architecture and function of biological membranes

Regulation of Polarized Morphogenesis

The role of glia in the development, maintenance and regeneration of the nervous system

Precision medicine, translational science, regeneration, organoids, high resolution imaging, computational modeling

RNA regulatory networks and RNA binding proteins during cardiovascular development and in cardiovascular disease

Restoration of Homeostasis in Disease

Cancer Biology, Tumor Cell of Origin and Tumor Microenvironment, Neurofibromatosis and Schwann Cell Biology, Skin and Hair Stem Cell Biology & Regeneration

Composition, Biophysics and Physiology of Cellular Membranes

Wnt/PCP signaling in inner ear development Mouse models for human deafness Wnt/PCP signaling in neural tube closure

Physiology & Biophysics

Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology

Mitochondrial regulation of innate immune and antiviral signaling

Obesity and Aging

Investigating the cell-biological foundations of development

Developmental Genetics, Evolution and Regeneration

Mechanisms of tissue/organ homeostasis and tumorigeensis

Chromosome segregation and aneuploidy in meiosis and mitosis

Proteoform Systems Biology: proteogenomic approaches to uncover the role of proteomic variation in human disease

Auditory Neurobiology

Regulation of neural stem cell proliferation during development and adulthood

Spatial Cell Biology. Neuronal Morphogenesis and Disease. Cancer Migration and Invasion.

Mechanisms of chromosome segregation in Mitosis and generation of Chromosomal Instability in tumors

Cell behavior and morphogenesis during early mouse development.

Regulation of cell-surface stability and intracellular trafficking of membrane proteins in epithelial cells

Endosomal function and dysfunction in neurons. Development of the nervous system: cytoskeleton and membrane traffic in axon and dendrite growth.

Investigating regeneration through genetics and single-cell analysis

Regulation of Gene Expression, Development and Tumor Progression by TGF beta Signaling

Cardiovascular Development and Cerebrovascular Pathologies

Mechanisms of Huntington's Disease Pathogenesis

Genetics, Functional Genomics, Epigenetics, Lung repair/regeneration, Metabolic regulation, Alveolar stem cells, Chromatin interaction, Innate immune response, Live-cell imaging