Microbiology

Basic and translational brain tumor research

Genetic approaches, cellular and molecular biology of intracellular pathogen infection

Engineering cancer-killing T cells to overcome obstacles in solid tumors

Innate immunity, Cell clearance, Inflammatory and autoimmune disease

Engineering programmable immunotherapies for solid tumors

Natural Killer Cells, Viral Immunity, Genetic basis of host resistance to viral infection, Tumor immunity, Immune cell regulation

Pathways to enhance T cell function in tumors.

Role of Arf family GTPases in vesicular transport and cytoskeleton assembly.<br> Cell Biology of bacterial pathogenesis. <br>The innate immune response to bacterial infection.

Herpes Simplex Virus Infection of Neurons

The maternal and infant microbiome in childhood growth and immunity

Cellular and molecular mechanisms of Neisserial pathogenesis

Host/pathogen Interaction - Chlamydia Infection

Ion channels and Ca2+-signaling in inflammation, immunity and tissue homeostasis

Systems Immunology, Cancer Systems Biology, , Neonatal and Maternal Immunology

Herpesvirus gene expression & RNA biology

Tumor microenvironment and mechanisms of tumor neovascularization

Immune mechanisms of pathogenic antibody production in allergy and autoimmunity

Innate immunity, chronic disease, host-parasite interactions, Toxoplasma gondii, proteomics

Neuroscience

Basement Membrane Structure and Metalloproteinases

RNA-protein interactions in antiviral immunity and autoimmune diseases.

Signal transduction in cancer cells

Mechanisms of Genetic and Metabolic Adaptation in the Malaria Parasite, Plasmodium falciparum

Immune regulation for HCV infection and chronic liver inflammation

Post Transcriptional Gene Regulation and the Molecular Biology of Human Retroviruses

Immune response to infectious disease in the CNS

Biodefense and emerging pathogens

The Role of Mitochondrial Fusion and Fission in Tumorigenesis.

Bacterial cell signaling, host-pathogen interactions, intestinal pathogens

Hematologic malignancies; bone marrow disorders; leukemia; large granular lymphocyte (LGL)

Neuron-glia communications, brain plasticity and homeostasis, glial responses to neurodegeneration

Understanding How Immunological Pathways Contribute to Neurodegenerative, Neurodevelopmental, Mental and Behavior Disorders

Immune System Regulation of Cardiometabolic Disease

Pathogenesis of diarrheagenic Escherichia coli and Shigella.

Mitochondrial regulation of innate immune and antiviral signaling

Mechanisms of tissue/organ homeostasis and tumorigeensis

Director of Graduate Studies for Microbiology, Immunology and Cancer Biology

Microbial Pathogenesis

Human Immunodeficiency Virus Gene Expression; Human Endogenous Viruses; SARS-CoV-2 Protein Trafficking; Post-transcriptional Gene Regulation

Anti-tumor immunity in brain tumors, Cancer Neuroscience

Influence of commensal microbes on immune homeostasis, anti-tumor immunity, and metastasis

Biomedical Engineering

Gram-positive pathogenesis; type VII secretion; impact of secreted effectors on host-pathogen interactions and immune responses

Immune Responses in asthma, pulmonary fibrosis, and lung injury.

Viral immunology, Cancer immunology, Aging, Mucosal Immunology

Prokaryotic immune systems, bacteriophage virology, programmed cell death, pore-forming proteins, evolution of immunity, cGAS-STING, protein engineering

B cell Analysis and Engineering

Cancer biology and immunology, Immuno-oncology, Immunometabolism, Genetically-engineered mouse models

The immune response to common cold and allergens in health and disease.

Researching fundamental roles of the epigenome in control of the context-specific transcriptional programs.

Unraveling the role of host microbe interactions in autoimmune diseases

Pathogenesis of infectious diseases and the development of new therapies and vaccines for infectious diseases and cancers.