Islet Cell Isolation GMP Facility
Islet transplantation is a minimally-invasive procedure that allows the replacement of the endocrine function of the pancreas only. Dr. Brayman is responsible for developing and establishing the Islet Isolation GMP Facility at UVA and has overseen the allo- and auto-transplantation of islets in more than 60 recipients. The Islet Transplant Program, headed by Dr. Brayman, uses an FDA-approved Human Islet Isolation class 10,000 GMP Facility at UVA for the isolation of clinical-grade pancreatic islets for transplants and currently participates with the NIH-sponsored Collaborative Islet Transplant Registry (CITR). Currently, there are two Human Islet isolation facilities at UVA, one at the Aurbach MR Building at Fontaine Medical Research Park, and the other at Pinn Hall. Both facilities provide human islets for transplantation and research, the only program of its kind in Virginia.
Media Highlights
Dr. Brayman’s Lab at UVA is one of only a few programs in the nation capable of performing Auto Islet Transplantation (AIT) and Total Pancreatectomy with Islet Autotransplantation (TPAIT). These groundbreaking procedures not only relieve the debilitating pain of chronic pancreatitis but also reduce—or even prevent—the onset of surgically induced diabetes. Through advanced science, a multidisciplinary care team, and ongoing research, we are transforming patient outcomes. Our work was recently highlighted in the UVA Surgery Annual Newsletter, as well as Medicine in Motion.