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Resident Endothelial Progenitors Make Themselves at Home

UVA Author: Karen Hirschi
Citation: Hirschi KK, Dejana E. Resident Endothelial Progenitors Make Themselves at Home. Cell Stem Cell. 2018;23(2):153-155. doi:10.1016/j.stem.2018.07.014

DOI: https://doi.org/10.1016/j.stem.2018.07.014
Pub-Med Number: 30075124


Vascular endothelial cells adapt to their microenvironment and physiological demands to perform many essential functions. Recent studies (McDonald et al., 2018; Wakabayashi et al., 2018) suggest that quiescent endothelial stem/progenitor cells reside within blood vessels and are activated in response to injury, suggesting they can be harnessed for therapeutic applications.