Center for Public Health Genomics

The Center for Public Health Genomics (CPHG) addresses questions in biology, public health, and medicine by developing and applying state-of-the-art genetic, genomic, and computational approaches to complex human diseases.

Research in the CPHG is focused on translational genomics and personalized medicine — moving basic discoveries in genetics and genomics into clinical settings with the goal of improving the delivery of health care and disease prevention.

Our research projects range from gene discovery to pharmacogenomics to mouse models of human disease. Labs in the CPHG offer graduate research and training opportunities through the UVA School of Medicine, Biomedical Engineering, and the College of Arts and Sciences graduate programs.

The Future

Public health genomics is a multi-disciplinary field that focuses on the effective and responsible translation of genetic information and technology for the benefit of population health. A major focus of our work translates genomic discoveries to appropriate population level assessments, policies and disease prevention programs.

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Center for Public Health Genomics Education

Graduate students identify CPHG mentors and conduct research in CPHG faculty laboratories. This research leads to degrees in disciplines that are typically multidisciplinary.

UVA Seminar Series

The Center for Public Health Genomics operates three seminar series: the Emerging Scholars in Genome Sciences Symposium in the Fall, the weekly Genome Sciences Seminar Series (GS3) in both Fall and Spring semesters, and the semi-monthly CPHG Research in Progress (CPHG-RIP) in both Fall and Spring semesters.

Current Schedule

Review of Human Genome IDs Stroke Risk Genes

Researchers seeking to better understand how our genes contribute to stroke risk have completed what is believed to be the largest and most comprehensive review of the human genome to identify genes that predispose people to ischemic stroke, the cause of approximately 85 percent of all strokes.

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CPHG’s Chongzhi Zang, PhD and Team Develop Powerful Analytical Tool to Advance Genomics and Disease Research

UVA Health School of Medicine researchers have developed an important new tool to help scientists sort signal from noise as they probe the genetic causes of cancer and other diseases.…

CPHG’s Kristen Naegle, PhD and Colleagues Develop Shining ‘KSTAR’ to Guide Cancer Treatments

Kristen Naegle, PhD UVA Cancer Center researchers have developed an algorithm that will improve cancer care by quickly and easily identifying patients who will benefit from powerful cancer drugs called kinase inhibitors.…

CPHG’s Nathan Sheffield, PhD Awarded $1.5M NIH Grant to Improve Methods for Analyzing Genome Locations

Nathan Sheffield, PhD, an associate professor in the Departments of Public Health Sciences, Biomedical Engineering, and Biochemistry and Molecular Genetics, and in the School of Data Science, was recently awarded…

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Recent Publications

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.