Miller, Clint L.
Primary Appointment
Associate Professor, Genome Sciences, Public Health Sciences
Education
- PhD, Pharmacology, University of Rochester
- Postdoc, Human Genetics, Stanford University
Contact Information
PO Box 800717
Center for Public Health Genomics, MSB 3231
Charlottesville, VA 22908
Telephone: 434-982-0502
Fax: 434-982-1815
Email: clintm@virginia.edu
Website: http://millerlab.org
Research Disciplines
Biochemistry, Bioinformatics and Genomics, Cardiovascular Biology, Computational Biology, Epigenetics, Experimental Pathology, Genetics, Molecular Biology, Molecular Pharmacology, Physiology
Research Interests
Genetic variation, Complex diseases, Coronary artery disease, Genomics, Epigenomics, Regulatory mechanisms, Vascular biology, Pharmacology and Physiology
Research Description
My laboratory's research focus involves the application of modern genomics and bioinformatics approaches to unravel complex and rare cardiovascular diseases. By integrating large-scale human genetic association and whole genome sequencing data with multi-omic profiles and clinically-relevant models, our work seeks to better understand causal disease mechanisms. We are dissecting the role of genetic and drug perturbations on vascular wall processes during atherosclerosis progression. We are also studying gene-gene and gene-environment interactions at the molecular level to further inform translational targeting of multiple risk loci.