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Le Lab

The Le Laboratory is composed of a core group of talented research scientists, postdoctoral fellows, students, and research associates. Our work bridges the fields of Cancer Biology, Developmental Biology, and Stem Cell Biology and focuses on neural-crest derived tissue development, regeneration, and tumorigenesis, in particular, the biology of neurofibromatosis, a group of genetic disorders that causes tumors to form on nerve tissue. The broad research goals of the Le Lab are to: 1) decipher mechanisms that initiate and drive human cancer, 2) generate robust in vivo and in vitro models to delineate tumor progression, and 3) develop novel therapeutic targets for human cancers. A related goal is to translate our basic scientific discoveries in the laboratory into human clinical trials.

Lu Q. Le Lab picture

Lab Members

The Le Laboratory is composed of a core group of talented research scientists, postdoctoral fellows, students and research associates. We are always looking for curious and driven people to join us!

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diagram of peripheral nerve and neurofibroma

Research

The Le Lab investigates how tumor cells of origin and tumor microenvironment interplay to regulate tumorigenesis. They also study stem cells in tumor, skin, and hair development.

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Research Opportunities

Latest research opportunities from the Le Lab.

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