Open-Angle Glaucoma / Ocular Hypertension
Athena Study
About The Study:
Principal Investigator: Bruce E. Prum, Jr., MD
Sponsored by Allergan, the purpose of this multi-center study is to investigate the safety and effectiveness of Bimatoprost SR compared with selective laser trabeculoplasty (SLT) in glaucoma or ocular hypertension.
All participants will be randomized to one of two study groups:
- Group A—SLT in the primary eye and Bimatoprost SR in the fellow eye
- Group B—Bimatoprost SR in the primary eye and SLT in the fellow eye
Participants participating in this study will make up to 22 scheduled study visits and 7 phone calls over a period of 14 months. Each visit will last anywhere from 2-5 hours.
Key Inclusion Criteria:
- Age ≥ 18 years
- IOP not adequately managed with topical medication for reasons other than medication efficacy—due to intolerance or nonadherence
- IOP ≥ 22 and ≤ 34 mmHg
- BCVA of 20/50 or better in the study eye
Key Exclusion Criteria:
- History of previous laser trabeculoplasty
- History of traumatic cataract and/or angle recession
- Central corneal thickness of < 480 or > 620 micrometers
- History of peripheral iridotomy/iridectomy in the inferior 180° of the iris
- Any history of trabeculectomy or other types of glaucoma surgery
- History of moderate or worse (≥2+) bulbar conjunctival hyperermia due to prostaglandin, prostamide, or prostaglandin use
For additional information about the trials or to refer a patient, contact the study coordinators:
- Ashton Leone, MPH at (434) 243-5737 or aml7q@virginia.edu
- Tamika Mercer at (434) 243-2852 or tmm2v@virginia.edu