Publications

For a full list of publications, see Ira Schulman’s bibliography at the National Library of Medicine.

Russo-Savage, L. and Schulman, I.G. Liver X receptors and liver physiology. Biochim. Biophys. Acta. Mol. Basis Dis. 1867:166121, 2021. PMID: 33713792. PMCID: In progress.
Liebergall, S.R., Angdisen, J., Chan, S.H., Chang, Y., Osborne, T.F., Koeppel, A.F., Turner, S.D. and Schulman, I.G. Inflammation triggers liver X receptor-dependent lipogenesis. Mol. Cell. Biol. 40:e00364-19, 2020. PMID: 31658997. PMCID: PMC6944475.
Belorusova, A.Y., Evertsson, E., Hovdal, D., Sandmark, J., Bratt, E. Maxwell, I., Schulman, I.G., Åkerblad, P., and Lindstedt, E-V.* Structural analysis identifies an escape route from the adverse effects of liver X receptor ligands. Communications Biology 431: doi: 10.1038/s42003-019-0675-0. PMID: 31799433. PMCID: PMC6874530.
Adamson, S.E., Polanowska-Grabowska, R., Marqueen, K., Griffiths, R., Angdisen, J., Breevoort, S.R., Schulman, I.G., and Leitinger, N.* Deficiency of Dab2 (Disabled Homolog 2) in Myeloid Cells Exacerbates Inflammation in Liver and Atherosclerotic Plaques in LDLR (Low-Density Lipoprotein Receptor)-Null Mice. Arteriosclerosis, Thrombosis, and Vascular Biology 38:1020-1029, 2018. PMID: 29599136. PMCID: PMC5920703.
Czimmerer, Z., Daniel, B., Horvath, A., Rückerl, D., Nagy, G., Kiss, M., Peloquin, M., Budai, M.,M., Cuaranta-Monroy, I., Simandi, Z., Steiner, L., Nagy Jr., B., Poliska, S., Banko, C., Basco, Z., Schulman, I.G., Sauer, S., Deleuze, J-F., Allen, J.E., Benko, S., and Nagy, L.* The transcription factor STAT6 mediates the direct repression of inflammatory enhancers and limits activation of alternatively polarized macrophages. Immunity. 28: 75-90, 2017. PMID: 29343442. PMCID: PMC5772169.
Schulman, I.G. Liver X Receptors link lipid metabolism and Inflammation. Febs Letters. 591:2978-2991, 2017. PMID: 28555747. PMCID: 5638683. Cited 64 times. IF = 3.5. Rank 98 out of 289 Biochemistry and Molecular Biology journals. Note this article was one of the top 20 downloaded FEBS Letters papers for 2017-2018.
Kick, E.K.*, Busch, B., Martin, R., Stevens, W., Bollu, V., Xie, Y., Boren, B., Nyman, M., Nanao, M., Nguyen, L., Plonowski, A., Schulman, I.G., Yan, G., Zhang, Y., Hou, X., Valente, M., Narayanan, R., Behnia, K., Rodrigues, D., Brock, B., Smalley, J., Cantor, G.H., Lupisella, J., Sleph, P., Grimm, D., Ostrowski, J., Wexler, R., Kirchgessner, T., Mohan, R. Discovery of highly potent LXRbeta agonists. Acs Med. Chem. Letters. 7:1207-1212, 2016. PMID: 27994765. PMCID: PMC5150697.
Fond, A.M., Lee, C.S., Kiss, R.S., Schulman, I.G., and Ravichandran K.S.* Apoptotic cells trigger a new membrane-initiated pathway in macrophages to increase ABCA1 and affect serum lipids. Journal of Clinical Investigation. 125:2748-2758, 2016. PMID: 26075824. PMCID: PMC4563683. IF=12.6.
Breevoort, S.R., Angdisen, J. and Schulman, I.G.* Macrophage Independent Regulation of Reverse Cholesterol Transport by Liver X Receptors. Arteriosclerosis, Thrombosis, and Vascular Biology 34:1650-1660, 2014. PMID: 24947527. PMCID: PMC4107336. Cited 25 time, IF=6.430. Rank 9 out of 65 Peripheral Vascular Disease journals.
Ignatova, I.D., and Schulman, I.G. Liver X receptors and atherosclerosis: it is not all cholesterol. Arteriosclerosis, Thrombosis, and Vascular Biology. 34:242-243, 2014. PMID: 24431422. PMCID: PMC3966182.
Leitinger, N.*, and Schulman, I.G. Phenotypic polarization of macrophages in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology: 33:1120-1126, 2013. PMID: 23640492. PMCID: PMC3745999.
Ignatovo-Torodova, I., Angdisen, J., Moran, E., and Schulman, I.G.* Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading. Mol. Endocrinol. 27: 1036-1047, 2013. PMID: 23686114. PMCID: PMC3706843. Note this article was selected by the editors to be highlighted on the cover and in an editorial for the July 2013 edition. Additionally, article was immediately made available on-line to non-subscribers without the typical 1 year embargo do the expected significant interest to the field.
Zhang, Y., Breevoort, S.R., Angdiesen, J., Fu, M., Schmidt, D.R., Holmstrom, S.R., Kliewer, S.A., Mangelsdorf, D.J., and Schulman, I.G.* Liver LXRa is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice. J. Clinical Investigation 122: 1688-1699, 2012. PMID: 22484817. PMCID: PMC3336978. Note S.R. Breevoort listed as Co-First Author.