Congratulations to Dionne Argyle, Recipient of an NIH F31 Ruth L. Kirschstein National Research Service Award

Dionne Argyle was awarded an NIH F31 individual predoctoral Ruth L. Kirschstein National Research Service Award from the National Heart, Lung and Blood Institute in September 2022. Dionne is a fifth year PhD candidate in the laboratory of Dr. Bradley Gelfand in the Department of Ophthalmology. She is pursuing her training in the Molecular and Cellular Basis of Disease program, which confers the PhD degree in Experimental Pathology. Her current research is focused on investigating sexual dimorphism in the IgG1 antibody response in conditions of pathological angiogenesis. She notes that certain diseases and conditions are more prevalent in one sex versus another, and her research aims to understand the mechanisms that underly these observations. Studies in this field have led to a better understanding of genes on the Y chromosome and their functionality outside of fertility and spermiogenesis. She notes that working in this field has also driven home an appreciation for the bias that exists in research that fails to consider and incorporate both sexes. When asked what motivates her interests is science, Dionne highlighted that this has been a lifelong passion, going all the way back to childhood. She was always interested in science and fascinated by the way things worked, from the healing of the human body to why certain chemicals explode when mixed together while some other combinations are harmless. For Dionne, science was a way to find answers to questions about which she was always curious. Based on this curiosity, she set out to pursue a career where she could make a difference and, for her, that will come from working at the bench. There are so many discoveries that have been made by proposing simple questions and she wants to be part of that. Working in the Center for Advanced Vision Science, Dionne has been surrounded by a diverse group that has shown her where she can go in the future. Her hope is to continue in research, possibly as a research scientist working in a field such as biotech, pharmaceuticals, or government. She believes that the knowledge and skills gained through her graduate studies will allow her to be successful in any of these areas.