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Gene Discovery Reveals New Targets for Treating Atherosclerosis, Inflammatory Diseases

ravichandranA group of genes that has been largely ignored by scientists could play critical roles in atherosclerosis (hardening of the arteries), inflammation, and likely obesity and other metabolic diseases, new research suggests.

“We came across the genes, called SLCs, kind of by accident,” said researcher Kodi Ravichandran. “Initially, just like everybody else, we were not paying much attention to the SLCs. But they kept coming up repeatedly in our gene expression analyses, and we realized this must be relevant. Then we took a serious dive into their biology, and we had a lot of fun surprises.” [Read more]