Wolf, Matthew J
Associate Professor, Medicine: Cardiovascular Medicine
- Residency, Internal Medicine, Duke University School of Medicine, Durham, NC
- Fellowship, Cardiology, Duke University School of Medicine, Durham, NC
- PhD, Biochemistry, Washington University School of Medicine
- MD, Washington University School of Medicine
Heart and Vascular Center Northridge
2nd floor, 1215 Lee St.
Charlottesville, VA 22908
Cardiovascular Biology, Genetics, Physiology
Identification of genes and pathways that cause or modify cardiac hypertrophy and heart failure.
Our mission is to understand how signaling molecules mediate cardiomyocyte growth, hypertrophy, and heart failure. We use novel approaches based on fruit fly genetics to identify genes that cause or modify cardiomyopathies and translate these findings using mammalian cell-based systems and transgenic mice. Our multidisciplinary approach employs state-of-the-art Optical Coherence Tomography, confocal microscopy, molecular and cell biology, proteomics, and physiology to understand cardiovascular disease.