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Author: zkr7e@virginia.edu

Jordan Aragon Receives F31 Award

1/25/2025

Jordon Aragon, a graduate student in the Hirschi Lab, has been awarded an NIH-NHLBI F31 predoctoral fellowship. Jordon's award focuses on how proper cell cycle control is necessary for endothelial…

Salmonella-induced cholesterol accumulation in infected macrophages suppresses autophagy via mTORC1 activation

1/1/2025

Authors: Holly M Torsilieri 1 2, Clint M Upchurch 3, Norbert Leitinger 3, James E Casanova  Citation: Torsilieri HM, Upchurch CM, Leitinger N, Casanova JE. Salmonella-induced cholesterol accumulation in infected macrophages suppresses autophagy via mTORC1 activation. Mol Biol…

General, open-source vertex modeling in biological applications using Tissue Forge

9/23/2024

UVA Author: Tien Comlekoglu Citation: Sego TJ, Comlekoglu T, Peirce SM, Desimone DW, Glazier JA. General, open-source vertex modeling in biological applications using Tissue Forge. Sci Rep. 2023 Oct 19;13(1):17886.…

Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm

9/23/2024

UVA Author: Tien Comlekoglu Citation: Comlekoglu T, Dzamba BJ, Pacheco GG, Shook DR, Sego TJ, Glazier JA, Peirce SM, DeSimone DW. Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry…

Wnt7b acts in concert with Wnt5a to regulate tissue elongation and planar cell polarity via noncanonical Wnt signaling

9/4/2024

UVA Author: Xiaowei Lu Citation: Xie N, Landin Malt A, Adylkhan A, Rodeman N, Moraes Borges R, Hwang D, Liu A, Smith C, Hogan A, Lu X. Wnt7b acts in…