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Author: zkr7e@virginia.edu

Jordan Aragon Receives F31 Award

1/25/2025

Jordon Aragon, a graduate student in the Hirschi Lab, has been awarded an NIH-NHLBI F31 predoctoral fellowship. Jordon's award focuses on how proper cell cycle control is necessary for endothelial…

Salmonella-induced cholesterol accumulation in infected macrophages suppresses autophagy via mTORC1 activation

1/1/2025

Authors: Holly M Torsilieri 1 2, Clint M Upchurch 3, Norbert Leitinger 3, James E Casanova  Citation: Torsilieri HM, Upchurch CM, Leitinger N, Casanova JE. Salmonella-induced cholesterol accumulation in infected macrophages suppresses autophagy via mTORC1 activation. Mol Biol…

General, open-source vertex modeling in biological applications using Tissue Forge

9/23/2024

UVA Author: Tien Comlekoglu Citation: Sego TJ, Comlekoglu T, Peirce SM, Desimone DW, Glazier JA. General, open-source vertex modeling in biological applications using Tissue Forge. Sci Rep. 2023 Oct 19;13(1):17886.…

Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry in collective cell migration of Xenopus mesendoderm

9/23/2024

UVA Author: Tien Comlekoglu Citation: Comlekoglu T, Dzamba BJ, Pacheco GG, Shook DR, Sego TJ, Glazier JA, Peirce SM, DeSimone DW. Modeling the roles of cohesotaxis, cell-intercalation, and tissue geometry…

Wnt7b acts in concert with Wnt5a to regulate tissue elongation and planar cell polarity via noncanonical Wnt signaling

9/4/2024

UVA Author: Xiaowei Lu Citation: Xie N, Landin Malt A, Adylkhan A, Rodeman N, Moraes Borges R, Hwang D, Liu A, Smith C, Hogan A, Lu X. Wnt7b acts in…

Rac1 and Nectin3 are essential for planar cell polarity-directed axon guidance in the peripheral auditory system

8/19/2024

Authors: Shaylyn Clancy, Nicholas Xie, Tess Eluvathingal Muttikkal, Jasmine Wang, Aray Adylkhan, Esha Fateh, Margaret Smith, Phillip Wilson, Matthew Smith, Arielle Hogan, Ann Sutherland, Xiaowei Lu Citation: Clancy S, Xie…