Recent Publications
Right place, right time – Spatial guidance of neuronal morphogenesis by septin GTPases
Radler MR, Spiliotis ET. Right place, right time - Spatial guidance of neuronal morphogenesis by septin GTPases. Curr Opin Neurobiol. 2022 Aug;75:102557. doi: 10.1016/j.conb.2022.102557. Epub 2022 May 21. PMID: 35609489; PMCID: PMC9968515.
35609489MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis
Wu Y, Paila U, Genet G, Hirschi KK. MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis. Dev Cell. 2023 Jun 6:S1534-5807(23)00240-X. doi: 10.1016/j.devcel.2023.05.007. Epub ahead of print. PMID: 37295435.
37295435Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice
Kam CY, Singh ID, Gonzalez DG, Matte-Martone C, Solá P, Solanas G, Bonjoch J, Marsh E, Hirschi KK, Greco V. Mechanisms of skin vascular maturation and maintenance captured by longitudinal imaging of live mice. Cell. 2023 May 25;186(11):2345-2360.e16. doi: 10.1016/j.cell.2023.04.017. Epub 2023 May 10. PMID: 37167971; PMCID: PMC10225355.
37167971Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest
Acharya BR, Fang JS, Jeffery ED, Chavkin NW, Genet G, Vasavada H, Nelson EA, Sheynkman GM, Humphries MJ, Hirschi KK. Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life Sci Alliance. 2023 May 17;6(8):e202201685. doi: 10.26508/lsa.202201685. PMID: 37197981; PMCID: PMC10192821.
37197981Rational engineering of lung alveolar epithelium
Leiby KL, Yuan Y, Ng R, Raredon MSB, Adams TS, Baevova P, Greaney AM, Hirschi KK, Campbell SG, Kaminski N, Herzog EL, Niklason LE. Rational engineering of lung alveolar epithelium. NPJ Regen Med. 2023 Apr 28;8(1):22. doi: 10.1038/s41536-023-00295-2. PMID: 37117221; PMCID: PMC10147714.
37117221Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone
Genet N, Genet G, Chavkin NW, Paila U, Fang JS, Vasavada HH, Goldberg JS, Acharya BR, Bhatt NS, Baker K, McDonnell SP, Huba M, Sankaranarayanan D, Ma GZM, Eichmann A, Thomas JL, Ffrench-Constant C, Hirschi KK. Connexin 43-mediated neurovascular interactions regulate neurogenesis in the adult brain subventricular zone. Cell Rep. 2023 Apr 11;42(4):112371. doi: 10.1016/j.celrep.2023.112371. Epub ahead of print. PMID: 37043357.
37043357Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data
de Souza VBC, Jordan BT, Tseng E, Nelson EA, Hirschi KK, Sheynkman G, Robinson MD. Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data. Genome Biol 24, 91 (2023). https://doi.org/10.1186/s13059-023-02923-y
Pyramidal neuron morphogenesis requires a septin network that stabilizes filopodia and suppresses lamellipodia during neurite initiation
Radler MR, Liu X, Peng M, Doyle B, Toyo-Oka K, Spiliotis ET. Pyramidal neuron morphogenesis requires a septin network that stabilizes filopodia and suppresses lamellipodia during neurite initiation. Curr Biol. 2023 Feb 6;33(3):434-448.e8. doi: 10.1016/j.cub.2022.11.043. Epub 2022 Dec 19. PMID: 36538929; PMCID: PMC9905282.
36538929Septins mediate a microtubule-actin crosstalk that enables actin growth on microtubules
Nakos K, Alam MNA, Radler MR, Kesisova IA, Yang C, Okletey J, Tomasso MR, Padrick SB, Svitkina TM, Spiliotis ET. Septins mediate a microtubule-actin crosstalk that enables actin growth on microtubules. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2202803119. doi: 10.1073/pnas.2202803119. Epub 2022 Dec 7. PMID: 36475946; PMCID: PMC9897426.
36475946Endothelial cell cycle state determines propensity for arterial-venous fate.
Chavkin NW, Genet G, Poulet M, Jeffery ED, Marziano C, Genet N, Vasavada H, Nelson EA, Acharya BR, Kour A, Aragon J, McDonnell SP, Huba M, Sheynkman GM, Walsh K, Hirschi KK. Endothelial cell cycle state determines propensity for arterial-venous fate. Nat Commun. 2022 Oct 6;13(1):5891. doi: 10.1038/s41467-022-33324-7. PMID: 36202789; PMCID: PMC9537338.
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