Recent Publications
Lacripep for the Treatment of Primary Sjögren’s-Associated Ocular Surface Disease: Results of the First-In-Human Study
Tauber J, Laurie GW, Parsons EC, Odrich MG; Lacripep study group*; Lacripep study group*. Lacripep for the Treatment of Primary Sjögren's-Associated Ocular Surface Disease: Results of the First-In-Human Study. Cornea. 2022 Aug 3. doi: 10.1097/ICO.0000000000003091. Epub ahead of print.
35942530Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality
Sano S, Horitani K, Ogawa H, Halvardson J, Chavkin NW, Wang Y, Sano M, Mattisson J, Hata A, Danielsson M, Miura-Yura E, Zaghlool A, Evans MA, Fall T, De Hoyos HN, Sundström J, Yura Y, Kour A, Arai Y, Thel MC, Arai Y, Mychaleckyj JC, Hirschi KK, Forsberg LA, Walsh K. Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality. Science. 2022 Jul 15;377(6603):292-297. doi: 10.1126/science.abn3100. Epub 2022 Jul 14. PMID: 35857592; PMCID: PMC9437978.
35857592A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells
Coon BG, Timalsina S, Astone M, Zhuang ZW, Fang J, Han J, Themen J, Chung M, Yang-Klingler YJ, Jain M, Hirschi KK, Yamamato A, Trudeau LE, Santoro M, Schwartz MA. A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells. J Cell Biol. 2022 Jul 4;221(7):e202109144. doi: 10.1083/jcb.202109144. Epub 2022 Jun 13. PMID: 35695893; PMCID: PMC9198948.
PMC9198948Dynein Is Required for Rab7-Dependent Endosome Maturation, Retrograde Dendritic Transport, and Degradation
Yap CC, Digilio L, McMahon LP, Wang T, Winckler B. Dynein Is Required for Rab7-Dependent Endosome Maturation, Retrograde Dendritic Transport, and Degradation. J Neurosci. 2022 Jun 1;42(22):4415-4434. doi: 10.1523/JNEUROSCI.2530-21.2022. Epub 2022 Apr 26. PMID: 35474277; PMCID: PMC9172292.
35474277Septins guide noncentrosomal microtubules to promote focal adhesion disassembly in migrating cells
Merenich D, Nakos K, Pompan T, Donovan SJ, Gill A, Patel P, Spiliotis ET, Myers KA. Septins guide noncentrosomal microtubules to promote focal adhesion disassembly in migrating cells. Mol Biol Cell. 2022 May 1;33(5):ar40. doi: 10.1091/mbc.E21-06-0334. Epub 2022 Mar 11. PMID: 35274967; PMCID: PMC9282018.
35274967Characterization of convergent thickening, a major convergence force producing morphogenic movement in amphibians
David R Shook, Jason WH Wen, Ana Rolo, Michael O'Hanlon, Brian Francica, Destiny Dobbins, Paul Skoglund, Douglas W DeSimone, Rudolf Winklbauer, Raymond E Keller. eLife, April 2022.
35404236Dynamics and distribution of endosomes and lysosomes in dendrites
Yap CC, Mason AJ, Winckler B. Dynamics and distribution of endosomes and lysosomes in dendrites [published online ahead of print, 2022 Apr 7]. Curr Opin Neurobiol. 2022;74:102537. doi:10.1016/j.conb.2022.102537
35398663A multi-organ chip with matured tissue niches linked by vascular flow
Ronaldson-Bouchard K, Teles D, Yeager K, Tavakol DN, Zhao Y, Chramiec A, Tagore S, Summers M, Stylianos S, Tamargo M, Lee BM, Halligan SP, Abaci EH, Guo Z, Jacków J, Pappalardo A, Shih J, Soni RK, Sonar S, German C, Christiano AM, Califano A, Hirschi KK, Chen CS, Przekwas A, Vunjak-Novakovic G. A multi-organ chip with matured tissue niches linked by vascular flow. Nat Biomed Eng. 2022 Apr;6(4):351-371. doi: 10.1038/s41551-022-00882-6. Epub 2022 Apr 27. PMID: 35478225; PMCID: PMC9250010.
35478225Spatial regulation of endosomes in growing dendrites
Yap CC, Winckler B. Spatial regulation of endosomes in growing dendrites [published online ahead of print, 2022 Mar 17]. Dev Biol. 2022;486:5-14. doi:10.1016/j.ydbio.2022.03.004
35306006Prdm6 controls heart development by regulating neural crest cell differentiation and migration
Hong L, Li N, Gasque V, Mehta S, Ye L, Wu Y, Li J, Gewies A, Ruland J, Hirschi KK, Eichmann A, Hendry C, van Dijk D, Mani A. Prdm6 controls heart development by regulating neural crest cell differentiation and migration. JCI Insight. 2022 Feb 2;7(4):e156046
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