Recent Publications

Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes

J Cell Biol. 2018 Jun 15. pii: jcb.201711039. doi: 10.1083/jcb.201711039. [Epub ahead of print]

Yap CC1, Digilio L2, McMahon LP2, Garcia ADR3, Winckler B4.


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Transcytosis of TrkA leads to diversification of dendritic signaling endosomes.

Barford K, Keeler A, McMahon L, McDaniel K, Yap CC, Deppmann CD, Winckler B.

Sci Rep. 2018 Mar 16;8(1):4715. doi: 10.1038/s41598-018-23036-8.


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Extracellular Matrix (ECM) and the Sculpting of Embryonic Tissues

Curr Top Dev Biol. 2018;130:245-274. doi: 10.1016/bs.ctdb.2018.03.006.

Dzamba BJ1, DeSimone DW2


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Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells.

Mol Biol Cell. 2018 Jan 15;29(2):166-179. doi: 10.1091/mbc.E17-08-0495. Epub 2017 Nov 22.

Janisch KM, McNeely KC, Dardick JM, Lim SH, Dwyer ND.


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Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments

MBio. 2018 Jan 2;9(1). pii: e01818-17. doi: 10.1128/mBio.01818-17.

Hulseberg CE, Fénéant L, Szymańska KM, White JM.


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Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND “OFF-PATHWAY” CELLULAR MECHANISMS.

Yap CC, Digilio L, McMahon L, Roszkowska M, Bott CJ, Kruczek K, Winckler B.
J Biol Chem. 2016 Dec 23;291(52):26613-26626


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Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability

Biophys J. 2017 Nov 7;113(9):1912-1915. doi: 10.1016/j.bpj.2017.09.014. Epub 2017 Oct 13.

Kreutzberger AJB, Kiessling V, Liang B, Yang ST, Castle JD, Tamm LK.


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Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of mesendoderm tissue at gastrulation

Pooja R. Sonavane, Chong Wang, Bette Dzamba, Gregory F. Weber, Ammasi Periasamy, Douglas W. DeSimone. Pub med #28982683


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A new Rab7 effector controls phosphoinositide conversion in endosome maturation

J Cell Biol. 2017 Oct 2;216(10):2995-2997. doi: 10.1083/jcb.201709034. Epub 2017 Sep 19.

Casanova JE, Winckler B.


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Structure of the Ebola Virus Envelope Protein MPER/TM Domain and its Interaction with the Fusion Loop Explains their Fusion Activity

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7987-E7996. doi: 10.1073/pnas.1708052114. Epub 2017 Sep 5.

Lee J, Nyenhuis DA, Nelson EA, Cafiso DS, White JM, Tamm LK.


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