Recent Publications

Different Doublecortin (DCX) Patient Alleles Show Distinct Phenotypes in Cultured Neurons: EVIDENCE FOR DIVERGENT LOSS-OF-FUNCTION AND “OFF-PATHWAY” CELLULAR MECHANISMS.

Yap CC, Digilio L, McMahon L, Roszkowska M, Bott CJ, Kruczek K, Winckler B.
J Biol Chem. 2016 Dec 23;291(52):26613-26626


Read The Full Article

The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes.

Yap CC, Digilio L, McMahon L, Winckler B.

Sci Rep. 2017 Sep 5;7(1):10481. doi: 10.1038/s41598-017-07667-x.


Read The Full Article

The neurotrophin receptor signaling endosome: where trafficking meets signaling

Barford K, Deppmann C, Winckler B.
Dev Neurobiol. 2016 Aug 9. doi: 10.1002/dneu.22427.


Read The Full Article

BMP and retinoic acid regulate anterior-posterior patterning of the non-axial mesoderm across the dorsal-ventral axis.

Naylor RW, Skvarca LB, Thisse C, Thisse B, Hukriede NA, Davidson AJ.
Nat Commun. 2016 Jul 13;7:12197. doi: 10.1038/ncomms12197. PMID:27406002


Read The Full Article

Recombinant production of enzymatically active male contraceptive drug target hTSSK2 – Localization of the TSKS domain phosphorylated by TSSK2.

Shetty J, Sinville R, Shumilin IA, Minor W, Zhang J, Hawkinson JE, Georg GI, Flickinger CJ, Herr JC Jan 4;121:88-96. doi: 10.1016/j.pep.2016.01.009. PMID:26777341


Read The Full Article

HIV gp41–mediated membrane fusion occurs at edges of cholesterol-rich lipid domains

Sung-Tae Yang, Volker Kiessling, James A Simmons, Judith M White & Lukas K Tamm
Nature Chemical Biology 11, 424–431 (2015) doi:10.1038/nchembio.1800
Received 04 December 2014 Accepted 25 March 2015 Published online 27 April 2015
PMID: 25915200


Read The Full Article

Ebola Virus and Severe Acute Respiratory Syndrome Coronavirus Display Late Cell Entry Kinetics: Evidence that Transport to NPC1+ Endolysosomes Is a Rate-Defining Step.

Rebecca M. Mingo, James A. Simmons, Charles J. Shoemaker*, Elizabeth A. Nelson, Kathryn L. Schornberg, Ryan S. D'Souza,
James E. Casanova and Judith M. White
April 2016


Read The Full Article

Ebolavirus Glycoprotein Directs Fusion through NPC1+ Endolysosomes

James A. Simmonsa, Ryan S. D'Souzaa, Margarida Ruasb, Antony Galioneb, James E. Casanovaa and Judith M. White
Journal of Virology, Aptil 2016


Read The Full Article

IQGAP3 is essential for cell proliferation and motility during zebrafish embryonic development

Fang X, Zhang B, Thisse B, Bloom GS, Thisse C.
Cytoskeleton (Hoboken). 2015 Aug;72(8):422-33. doi: 10.1002/cm.21237. Epub 2015 Sep 7


Read The Full Article

... Next »