Recent Publications

p53 deletion rescues lethal microcephaly in a mouse model with neural stem cell abscission defects

Hum Mol Genet. 2018 Oct 9. doi: 10.1093/hmg/ddy350. [Epub ahead of print]

Little JN1,2,3, Dwyer ND1.


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Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures.

J Infect Dis. 2018 Jun 25. doi: 10.1093/infdis/jiy304. [Epub ahead of print]

Dyall J1, Nelson EA2, DeWald LE1, Guha R3, Hart BJ1, Zhou H1, Postnikova E1, Logue J1, Vargas WM1, Gross R1, Michelotti J1, Deiuliis N1, Bennett RS1, Crozier I1, Holbrook MR1, Morris PJ3, Klumpp-Thomas C3, McKnight C3, Mierzwa T3, Shinn P3, Glass PJ4, Johansen LM5, Jahrling PB1,6, Hensley LE1, Olinger GG Jr1, Thomas C3, White JM2.


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Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes

J Cell Biol. 2018 Jun 15. pii: jcb.201711039. doi: 10.1083/jcb.201711039. [Epub ahead of print]

Yap CC1, Digilio L2, McMahon LP2, Garcia ADR3, Winckler B4.


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Alteration of transporter activities in the epididymides of infertile initial segment-specific Pten knockout mice

Biol Reprod. 2018 Mar 24. doi: 10.1093/biolre/ioy073. [Epub ahead of print]

Xu B1, Turner SD2, Hinton BT1.


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Protein tyrosine kinase 7 regulates extracellular matrix integrity and mesenchymal intracellular RAC1 and myosin II activities during Wolffian duct morphogenesis.

Dev Biol. 2018 Jun 1;438(1):33-43. doi: 10.1016/j.ydbio.2018.03.011. Epub 2018 Mar 23.

Xu B1, Santos SAA2, Hinton BT3.


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Control of insulin granule formation and function by the ABC transporters ABCG1 and ABCA1 and by oxysterol binding protein OSBP.

Mol Biol Cell. 2018 May 15;29(10):1238-1257. doi: 10.1091/mbc.E17-08-0519. Epub 2018 Mar 22.

Hussain SS1, Harris MT1, Kreutzberger AJB2,3, Inouye CM1, Doyle CA1, Castle AM1, Arvan P4, Castle JD1,3.


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Transcytosis of TrkA leads to diversification of dendritic signaling endosomes.

Barford K, Keeler A, McMahon L, McDaniel K, Yap CC, Deppmann CD, Winckler B.

Sci Rep. 2018 Mar 16;8(1):4715. doi: 10.1038/s41598-018-23036-8.


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Extracellular Matrix (ECM) and the Sculpting of Embryonic Tissues

Curr Top Dev Biol. 2018;130:245-274. doi: 10.1016/bs.ctdb.2018.03.006.

Dzamba BJ1, DeSimone DW2


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Kinesin-6 KIF20B is required for efficient cytokinetic furrowing and timely abscission in human cells.

Mol Biol Cell. 2018 Jan 15;29(2):166-179. doi: 10.1091/mbc.E17-08-0495. Epub 2017 Nov 22.

Janisch KM, McNeely KC, Dardick JM, Lim SH, Dwyer ND.


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Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments

MBio. 2018 Jan 2;9(1). pii: e01818-17. doi: 10.1128/mBio.01818-17.

Hulseberg CE, Fénéant L, Szymańska KM, White JM.


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