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Publications

1. Sun, W.W., Krystofiak, E.S., Leo-Macias, A., Cui, R., Sesso, A., Weigert, R., Ebrahim, S., Kachar, B. “Nanoarchitecture and dynamics of the mouse enteric glycocalyx examined by freeze-etching electron tomography and intravital microscopy.” Commun. Biol. 2020 Jan 7;3(1):5.

2. Ebrahim, S., Chen, D., Weiss, M., Malec, L., Ng, Y., Rebustini, I., Krystofiak, E., Hu, L., Liu, J., Masedunskas, A., Hardeman, E., Gunning, P., Kachar, B., Weigert, R. “Dynamic polyhedral actomyosin lattices remodel micron-scale curved membranes during exocytosis in live mice.” Nat Cell Biol. 2019 Aug;21(8):933-939.

3. Ebrahim, S., and Weigert, R. “Intravital microscopy in mammalian multicellular organisms.” Curr Opin Cell Biol. 2019 May 21;59:97-103.

4. Shitara, A., Malec, L., Ebrahim, S., Chen, D., Bleck, C., Hoffman, M.P., Weigert, R. “Cdc42 negatively regulates endocytosis during apical membrane maintenance in live animals.” Mol Biol Cell. 2019 Feb 1;30(3):324-332.

5. Ebrahim, S., Liu., J, Weigert, R. “The Actomyosin Cytoskeleton Drives Micron-Scale Membrane Remodeling In Vivo Via the Generation of Mechanical Forces to Balance Membrane Tension Gradients.” BioEssays. 2018 Sept 40 (9):e1800032. (Invited Review)

6. Beurg, M., Cui, R., Goldring, A.C., Ebrahim, S., Fettiplace, R., Kachar, B. “Variable number of TMC1- dependent mechanotransducer channels underlie tonotopic conductance gradients in the cochlea.” Nature Communications. 2018 Jun 5;9(1):2185.

7. Ebrahim, S., Milberg, O., Weigert, R. “Isoform-specific roles of NMII drive membrane remodeling in vivo.” Cell Cycle. 2017 Oct 18; 16(20):1851-1852. (Invited Review)

8. Milberg, O.*, Shitara, A.*, Ebrahim,S.*, Masedunskas, A., Tora, M., Tran, D.T., Chen, Y., Conti, M.A., Adelstein, R.S., Ten Hagen, K.G., Weigert, R. “Concerted actions of distinct nonmuscle myosin II isoforms drive intracellular membrane remodeling in live animals.” Journal of Cell Biology. 2017 Jun 9; pii: jcb.201612126.

9. Fan, J., Jia, L., Li, Y., Ebrahim, S., May-Simera, H., Wood, A., Morell, R.J., Liu, P., Lei, J., Kachar, B., Belluscio, L., Qian, H., Li, T., Li, W., Wistow, G., Dong, L. “Maturation arrest in early postnatal sensory receptors by deletion of the miR-183/96/182 cluster in mouse.” Proc Natl Acad Sci USA. 2017 May 23;114(21).

10. Ebrahim, S., Ingham, N., Rogers, M., Cui, R., Kachar, B., Lewis, M.A., Pass, J., Steel, K.P. “Alternative splice forms influence hearing and vestibular functions of whirlin in mechanosensory hair cells.” Cell Reports. 2016 May3; 15(5): 935-43.

11. Ebrahim, S., Avenarius, M.R., Grati, M., Krey, J.F., Windsor, A.M., Sousa, A.D., Ballesteros, A., Cui, R., Millis, B.A., Salles, F.T., Baird, M.A., Davidson, M.W., Jones, S.M., Choi, D., Dong, L., Raval, M., Yengo, C.M., Barr-Gillespie, P.G., Kachar, B. “Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.” Nature Communications. 2016 Mar 1; 7: 10833.

12. Kurima, K.*, Ebrahim, S.*, Millis, B.A., Fujikawa, T., Asai, Y., Holt, J.R., Griffith, A.J., Kachar, B. “TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia.” Cell Reports. 2015 Sep 8; 12(10): 1606-1617.

13. Yochelis, A., Ebrahim, S., Naoz, M., Millis, B., Cui, R., Kachar, B., Gov, N.S. “Self-organization of waves and pulse trains by molecular motors in cellular protrusions” Scientific Reports. 2015 Sep 3; 5:13521.

14. Ebrahim, S. and Kachar, B. “Myosin transcellular networks regulate epithelial architecture” Cell Cycle. 2013 Sep 15; 12(18): 2931–2932. (Invited Review)

15. Ebrahim, S.*, Fujita, T*., Millis, B.A., Kozin, E., Ma, X., Kawamoto, S., Baird, M.A., Davidson, M., Yonemura, S., Hisa, Y., Conti, M.A., Adelstein, R.S., Sakaguchi, H., Kachar, B. “NMII forms a contractile transcellular sarcomeric network to regulate apical cell junctions and tissue geometry.” Current Biology. 2013 Apr 22;23(8):731-6.
Featured in a cover page article in the NIH Intramural Research Magazine, The Catalyst, on the NIDCD website, science blogs and F1000 Prime.