David Feith, PhD
PRIMARY APPOINTMENT:
Associate Professor
Medicine: Hematology and Oncology
CONTACT:
Division of Hematology & Oncology
Po Box 800716
Charlottesville, VA 22908
Telephone: 434.243.8067
Email: djf2g@virginia.edu
RESEARCH INTERESTS:
Cell signaling and survival pathways, genetic alterations, and development of experimental therapeutics; large granular lymphocyte (LGL) leukemia; acute myeloid leukemia (AML); the role of polyamines in normal and neoplastic growth in the skin, upper aerodyne.
RESEARCH SUMMARY:
Cell signaling and survival pathways, genetic alterations, and development of experimental therapeutics; large granular lymphocyte (LGL) leukemia; acute myeloid leukemia (AML); the role of polyamines in normal and neoplastic growth in the skin, upper aerodigestive tract, mammary gland and neuroblastoma; genetic manipulation of polyamine regulatory proteins in mouse models; mouse models of cancer.
- Morad SA, Tan SF, Feith DJ, Kester M, Claxton DF, Loughran TP, Barth BM, Fox TE, Cabot MC, Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia-Impact on enzyme activity and response to cytotoxics., 2015; Biochimica et biophysica acta. 1851(7) 919-28. PMID: 25769964
- Yan Y, Olson TL, Nyland SB, Feith DJ, Loughran TP, Emergence of a STAT3 mutated NK clone in LGL leukemia., 2015; Leukemia research reports. 4(1) 4-7. PMID: 25709890 | PMCID: PMC4327758