New Publication from Dr. Zimmer’s Lab-Congratulations!

Congratulations to Dr. Zimmer, Jacob Morgan and Joshua McNamara for their recent publication in Nature Structural and Molecular Biology. In this paper they describe how the bacterial signaling molecule cyclic di-GMP stimulates the biosynthesis of bacterial cellulose. Zimmer and colleagues crystallized a complex of c-di-GMP with membrane-bound cellulose synthase and by comparison with their previously published apo-enzyme (Nature 493:181) found an allosteric mechanism of catalysis. This work represents the first molecular description any c-di-GMP-activated enzyme. For the new NSMB paper … [Read more...]

Congratulations to Center Director Dr. Lukas Tamm, Recipient of the 2014 Humboldt Research Award

Congratulations to Center for Membrane and Cell Physiology Director, Lukas Tamm, PhD, Professor of Molecular Physiology and Biological Physics, for being elected to receive a Humboldt Research Award. This honor is awarded by the Alexander von Humboldt Foundation, a group dedicated to promoting academic cooperation between excellent scientists and scholars from abroad and from within Germany. According to the foundation’s website, “The award is granted in recognition of a researcher’s entire achievements to date to academics whose fundamental discoveries, new theories, or insights have had a … [Read more...]

CMCP Linda Columbus has received the 2014 Outstanding Faculty Award.

University of Virginia chemist Linda Columbus and infectious diseases researcher and physician Dr. William A. Petri have received the state’s highest honor for professors, the Outstanding Faculty Award. - See more at: … [Read more...]

Jake Morgan of the Zimmer Lab wins the NSF 2013 Graduate Research Fellowship

  2013 National Science Foundation Graduate Research Fellowship Program awarded to Jake Morgan of Dr. Jochen Zimmer’s Lab. Congratulations to Jake Morgan! NSF received over 13,000 submitted applications for the 2013 competition, and made 2,000 award offers. Congratulations to the awardees and honorable mentions. The National Science Foundation’s Graduate Research Fellowship Program (GRFP) helps ensure the vitality of the human resource base of science and engineering in the United States and reinforces its diversity.  The program recognizes and supports outstanding graduate … [Read more...]

Michael Wiener’s Lab in the News: Protein structure discovery could lead to better treatments for HIV, early aging

Dr. Michael Wiener’s Lab has been in the news, focusing on exciting developments. Click HERE to see the video from NewsPlex From the University’s PR department: By Josh Barney, Lead editor, University of Virginia Health System 434-243-1988   CHARLOTTESVILLE, Va., March 29, 2013 – Researchers at the University of Virginia School of Medicine have determined the molecular structure of a protein whose mutations have been linked to several early aging diseases and side effects for common HIV and AIDS medications. This breakthrough could eventually help researchers develop new … [Read more...]

What do you and Ben Franklin have in common? He was a Membrane Biophysicist.

Biophysical Journal published Benjamin Franklin, Philadelphia’s Favorite Son, was a Membrane Biophysicist, written byDa-Neng Wang, Heather Stieglitz, Jennifer Marden, and Lukas Tamm.  When it first came out, this article ranked number one of Top 20 Papers by download. You can even “Like” it on Facebook! Volume 104, Issue 2, 287-291, 22 January 2013 … [Read more...]

New discovery in blood pressure regulation from the Isakson Lab published in Nature

      UVA Discovery Helps Explain Blood Pressure Regulation May Point to New Therapeutic Target for Treating High Blood Pressure CHARLOTTESVILLE, Va., Nov. 13, 2012 – Researchers at the University of Virginia School of Medicine have shed new light on blood pressure regulation with the discovery of an unexpected mechanism by which hemoglobin controls the delivery of nitric oxide. The findings may point to a new therapeutic target for treating high blood pressure and may have far-reaching implications for many organ systems and illnesses. Hemoglobin is best known … [Read more...]