Annex, Brian H.
Lantheus Medical Imaging Distinguished Professor of Cardiovascular Medicine; Chief, Division of Cardiovascular Medicine, Medicine: Cardiovascular Medicine
- Clinical Fellowship, Cardiology, Duke University School of Medicine, Durham, NC
- Clinical Fellowship, Interventional Cardiology, William Beaumont Hospital
- MD, , Yale School of Medicine
- Residency, Internal Medicine, Tufts University School of Medicine
Angiogenesis; peripheral arterial disease (PAD); gene therapy
Dr. Annex's clinical and research interests include a multidisciplinary program in angiogenesis (the growth of new blood vessels) that is focused mainly on peripheral arterial disease (PAD), in which blockages in arteries cause a series of clinical problems. His group is involved in a number of bench-to-bedside studies, including investigations of the causes of blockages in arteries outside the heart, in case of the legs the response of the muscle and new arterial growth that follow the blockages, and the impact that diabetes mellitus plays in PAD. Included among the array studies are gene or cell therapy clinical investigation to promote blood vessel growth in patients with PAD, as well as studies of exercise training, and pre-clinical models of PAD.