Brian Annex

Annex, Brian H.

Primary Appointment

Lantheus Medical Imaging Distinguished Professor of Cardiovascular Medicine; Chief, Division of Cardiovascular Medicine, Medicine: Cardiovascular Medicine


  • Clinical Fellowship, Cardiology, Duke University School of Medicine, Durham, NC
  • Clinical Fellowship, Interventional Cardiology, William Beaumont Hospital
  • MD, , Yale School of Medicine
  • Residency, Internal Medicine, Tufts University School of Medicine

Contact Information

PO Box 800158
UVA Medical Park Northridge
Charlottesville, VA 22903
Telephone: 434-243-1000
Fax: 434-244-7551

Research Disciplines

Cardiovascular Biology

Research Interests

Angiogenesis; peripheral arterial disease (PAD); gene therapy

Research Description

Dr. Annex's clinical and research interests include a multidisciplinary program in angiogenesis (the growth of new blood vessels) that is focused mainly on peripheral arterial disease (PAD), in which blockages in arteries cause a series of clinical problems. His group is involved in a number of bench-to-bedside studies, including investigations of the causes of blockages in arteries outside the heart, in case of the legs the response of the muscle and new arterial growth that follow the blockages, and the impact that diabetes mellitus plays in PAD. Included among the array studies are gene or cell therapy clinical investigation to promote blood vessel growth in patients with PAD, as well as studies of exercise training, and pre-clinical models of PAD.

Selected Publications