2025 MSSRP unmatched projects – Deadline for new projects to be posted has passed.

Preceptor: Bon Trinh, PhD
Department: Pathology/Cancer
Contact: Phone # (434) 243-8343, email: bontrinh@virginia.edu
Project title: Anti-leukemia activities of lead molecules in AML cell lines,
Project description: In collaboration with computer and data scientists, our group has been developing computational pipelines for the virtual screening of small molecules that target proteins associated with diseases such as acute myeloid leukemia (AML). The project aims to perform experimental validation of the anti-leukemia activities of lead molecules in AML cell lines, primary AML patient cells, and mouse models, which are readily available in the Trinh lab. The student(s) will have the opportunity to interact with a collaborative research team consisting of computational scientists, data scientists, medical pathologists, and experimentalists.

More details: https://tinyurl.com/trinhlaboratory
Previous successful MSSRP student story: Kevin Qiu, MD candidate
2024. First-author research paper in press on Epigenetics & Chromatin and broadcasted by ScienceCast
2024. Award winner, First-author research poster competition, Inaugural Research Computing Exhibition, UVA Research Computing Day
2024. First-author research poster presentation, ColdSpring Harbour conference on Systems Biology: Global regulation of gene expression.
2024. First-author research poster presentation, Pathology Research Day
2023. Medical Student Research Symposium with first-author poster presentation titled: “Controlling the Controller: Identification of Novel Enhancers of the Key Hematopoietic TF PU.1”

Preceptor: Melissa A. Little, PhD, MPH
Department: PHS
Contact: Phone # (434) 924-1935, email: mal7uj@virginia.edu
Project title: Tobacco prevention and control
Project description: The Center for Nicotine and Tobacco Research, directed by Melissa A. Little, PhD, MPH, aims to reduce tobacco-related disparities through the development and dissemination of sustainable community-based tobacco prevention and cessation interventions. Current research programs focus on promoting tobacco and nicotine prevention among youth, and cessation among rural, low income and active-duty military populations. The MSSRP students will have the opportunity to work across a variety of community-engaged projects that directly address tobacco prevention and control. Community partners include independent pharmacies in rural Appalachia, schools, Federally Qualified Health Centers, and the U.S. military. Additionally, there is an opportunity to be a part of manuscripts and presentations resulting from the research

Preceptor: Robin LeGallo, MD
Department: Pathology
Contact: Phone: (434) 409-0069, email: rdl3s@uvahealth.org
Project title: Clinical and research opportunities in areas of anatomic and clinical pathology
Project description: The summer internship in pathology will be provide clinical and research opportunities in areas of anatomic and clinical pathology. The students will work closely with residents and faculty in patient care areas and have both observational and active roles in surgical pathology, autopsy pathology and cytopathology. They will rotate through the clinical labs including hematopathology, blood bank, microbiology, cytogenetics and molecular pathology. The students will be included in appropriate didactic sessions held for the residents but will also have separate interactive instructional activities given by both faculty and residents. There will also be interaction and collaboration with pathology graduate students where there is the expectation of cross teaching in areas of interest. Research will be encouraged in the form of either case reports or as a part of a translational research project with expectation of co-authorship. Preference will be given to but is not limited to those interested in pursuing pathology as a career.

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