USCAP 2020 Representation

April 3, 2020 by kdk2g@virginia.edu   |   Leave a Comment

The University of Virginia’s Department of Pathology had another strong showing at the 2020 Annual Meeting of the United States and Canadian Academy of Pathology in Los Angeles, California. Thirteen original research abstracts were presented by UVA medical students, residents, fellows, and faculty.  Second-year resident Dr. Megan Dibbern was awarded the International Society of Gynecological Pathology’s prestigious W. Dwayne Lawrence Award for her platform presentation “Loss of MHC Class I Expression in PD-L1-positive HPV-Associated Cervical and Vulvar Neoplasia: A Mechanism of Resistance to Checkpoint Inhibition?”, while first-year resident Dr. Lisa Friedman was awarded 1st Place in the Gynecologic Poster section for her work entitled, “Loss of MHC Class I in Endometrial Carcinoma: A Possible Mechanism of Immunotherapeutic Resistance in Some MMR-Deficient and PD-L1-Positive Tumors.”  In other meeting highlights, Dr. Robin LeGallo helped lead the organization’s first annual session on Diversity & Inclusion with a talk focused on the healthcare of transgender individuals.  Dr. Anne Mills delivered a talk entitled “PD-L1 immunostaining in Cervical and Vulvar Cancer” to an audience of several hundred at the meeting of the International Society of Gynecological Pathology and a three-hour SAMs/CME course on Biomarkers in Gynecologic Pathology.  The most memorable part of the meeting, however, was the fun and fellowship that the UVA folks shared over Mediterranean food at the annual departmental meeting dinner.

Oral presentations:

 

ISGyP Companion Society Meeting, Presenter: Anne Mills

Title: PD-L1 immunostaining in Cervical and Vulvar Cancer

 

USCAP Focus on Diversity and Inclusion, Presenter: Robin LeGallo

Title: Healthcare of Transgender Individuals

 

Short Course, Presenter: Anne Mills

Title: Tests, Targets, and Treatments: Emerging Biomarkers in Gynecologic Carcinoma

 

Platform, Gynecologic Pathology, Presenter: Megan Dibbern

Title: Loss of MHC Class I Expression in PD-L1-positive HPV-Associated Cervical and Vulvar Neoplasia: A Mechanism of Resistance to Checkpoint Inhibition?

 

Poster Presentations

 

  • Presenter: Bre Ana David

Title: Mismatch Repair Deficiency and PD-L1 Expression in Sebaceous Carcinomas and Basal Cell Carcinomas with Sebaceous Features.

  • Presenter: Marge Moore

Title: The Targetable Immune Checkpoint VISTA is Highly Expressed in a Subset of Endometrial Carcinomas, Particularly Those Exhibiting Mismatch Repair Deficiency and PD-L1 Expression.

 

  • Presenter: Jacob Curley

Title: Looking Past PD-L1: Expression of Immune Checkpoint TIM-3 and its Ligand Galectin-9 in Cervical and Vulvar Squamous Neoplasia

 

  • Presenter: Lisa Friedman

Title: Loss of MHC Class I in Endometrial Carcinoma: A Possible Mechanism of Immunotherapeutic Resistance in Some MMR-Deficient and PD-L1-Positive Tumors.

 

  • Presenter: Ed Stelow

Title: Low-Grade Tubulo-Acinar Sinonasal Adenocarcinoma: A specific entity with recurrent beta-catenin mutations

  • Presenter: Brian Adkins

Title: Characterizing the Lymphocyte Environment in Hospital Autopsy

 

  • Presenter: Sarah Gradecki

Title: p16 and Rb Expression and High-Risk HPV Status of 18 Sebaceous Carcinomas of the Conjunctiva and Eyelid

  • Presenter: Bea Lopes

Title: Liver Metastases from Pituitary Carcinoma Mimicking Visceral Well-Differentiated Neuroendocrine Tumor

 

  • Presenter: Elisheva Shanes

Title: IDO Expression in Uterine Smooth Muscle Tumors: Implications for Immunotherapy 

 

  • Presenter: Marge Moore

Title: HLA-1 Loss is Common in Non-Small Cell Lung Cancer and May Contribute to Failure of Immune Checkpoint Therapy

 

  • Presenter: Brett Kurpiel

Title: MLH1-Hypermethylation and Mutation Status Among MLH1/PMS2-Deficient Endometrial Carcinomas: Results from a Universally Screened Population

  • Presenter: Taylor Jenkins

Title: PD-L1 and Mismatch Repair Status in Uterine Carcinosarcomas

 

 

 

 

 

 

 

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