Basic Science and Translational Research
Plastic Surgery Tissue Engineering Laboratory
PI(s): David Drake, M.D.; Shayn Peirce-Cottler, Ph.D.
Focus: Engineering of composite flexor tendon allografts, the biomechanical properties of ADM, and small joint allografts
Mission: Our work centers on better understanding the interface between engineered human cellular and tissue products and the body. Our primary foci of interest has been on developing models to study the recellularization of acellular dermal matrix, composite flexor tendon allografts, and small joint replacement in the hand and upper extremity.
Vascular and Tissue Bioengineering Laboratory
PI: Shayn Peirce-Cottler, Ph.D. – Associate Professor of Biomedical Engineering
Focus: Adipose stem cells and tissue engineering; vascular tissue engineering
Mission: A very active federally-funded laboratory focused on tissue engineering, angiogenesis and adipose stem cells. There are many projects currently being investigated that are germane to plastic surgery and wound healing.
Wound Healing Laboratory
PI: George T. Rodeheaver, Ph.D. – Professor of Plastic Surgery
Focus: Adhesive agents, bone void fillers, skin equivalents, surgical adhesions, surgical suture and needle mechanics, and wound irrigation
Mission: To provide an active investigative program that will improve the management and outcome of patients with malformed or damaged tissue. The wound healing laboratory was initiated in 1972 under the direction of George T. Rodeheaver, Ph.D. and continues under his leadership with a staff of eight. Dr. Rodeheaver, the lab’s research supervisor, director of animal surgery, and director of engineering act as a team in conducting the research program of the laboratory. In addition, they facilitate the research programs of the faculty, residents, medical students and undergraduate students affiliated with the Department of Plastic Surgery, as well as collaborate with faculty in other departments.
The Nettie Marie Jones Microsurgery Laboratory
Mission: The Nettie Marie Jones Microsurgical Center was founded in 1976 by a grant from the benefactor. This lab is one of the oldest continuously running microsurgery labs in the country. The Center provides instruction in microsurgery for medical students, residents, and faculty, including a one-week course of intense instruction in the techniques of dissection and repair of arteries, veins and nerves. In addition, medical students can elect to spend 2-4 weeks mastering basic microsurgical techniques. We also provide 24-hour coverage for replantation services. Interdisciplinary collaboration is encouraged through research and instructional activity. The lab is directed by Raymond F. Morgan, MD and staffed by Randy Amiss, RN.
There are several active clinical research projects being conducted within the Department of Plastic Surgery. Topics include abdominal wall reconstruction, hand surgery, burn treatments, and breast reconstruction among others.