Focused Ultrasound Cancer Immunotherapy Center

Focused Ultrasound (FUS) is a rapidly maturing medical technology wherein non-ionizing thermal and/or mechanical acoustic energy is deposited in solid tumors under image-guidance. This non-invasive technology may be tuned to synergize with both nascent and established immunotherapies to control primary and disseminated disease.

The University of Virginia (UVA) FUS Cancer Immunotherapy Center was recently formed through investments from the University of Virginia, the Commonwealth of Virginia, and the FUS Foundation. Our mission is to accelerate the discovery and translation of therapeutic FUS immuno-oncology strategies for a number of cancer indications. In so doing, we wish to differentiate UVA as the worldwide leader in translational FUS immuno-oncology research. Our center benefits significantly by being formally affiliated with the UVA Comprehensive Cancer Center.

Focused Ultrasound Foundation

The UVA Focused Ultrasound Cancer Immunotherapy Center receives substantial support from the Focused Ultrasound Foundation. Their mission is to accelerate the development of new applications of focused ultrasound and its widespread adoption as a standard of care.

NP delivery

Research Areas

Investigators in the center use numerous approaches to study how both thermal and mechanical forms of focused ultrasound can augment immune responses against primary and metastatic disease.

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Theraclion Echopulse

Focused Ultrasound Immunotherapy Resources

The Focused Ultrasound Cancer Immunotherapy Center houses a wide array of pre-clinical and clinical focused ultrasound equipment, as well as ample resources for immune profiling.

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Craig Slingluff and Lynn Dengel

Clinical Trials

Several clinical trials combining focused ultrasound with chemo- and immunotherapeutic drugs are currently underway.

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