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Publications

Radiation-guided nanoparticles enhance the efficacy of PARP inhibitors in primary and metastatic BRCA1-deficient tumors via immunotherapy

Khoury R, Longobardi G, Barnatan TT, Venkert D, García Alvarado A, Yona A, Green Buzhor M, Shahar S, Wang Q, Acúrcio RC, Guedes RC, Florindo HF, Zhao JJ, Satchi-Fainaro R. J Control Release. 2025 Jul 10;383:113812. doi: 10.1016/j.jconrel.2025.113812. Epub 2025 May 2. PMID: 40319918.
https://pubmed.ncbi.nlm.nih.gov/40319918/

ACAT1 regulates tertiary lymphoid structures: A target for enhancing immunotherapy in non-small cell lung cancer

O’Keefe S, Wang Q#. J Clin Invest. 2025 Apr 1;135(7):e191094. doi: 10.1172/JCI191094. PMID: 40166937. #: Corresponding author.
https://www.jci.org/articles/view/191094

Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response

He X, Wang Q, Cheng X, Wang W, Li Y, Nan Y, Wu J, Xiu B, Jiang T, Bergholz JS, Gu H, Chen F, Fan G, Sun L, Xie S, Zou J, Lin S, Wei Y, Lee J, Asara JM, Zhang K, Cantley LC, Zhao JJ. Cell. 2025 Feb 27:S0092-8674(25)00145-X. doi: 10.1016/j.cell.2025.01.043. Epub ahead of print. PMID: 40023152.
https://pubmed.ncbi.nlm.nih.gov/40023152/

 

 

PI3Kβ controls immune evasion in PTEN-deficient breast tumours

PI3Kβ controls immune evasion in PTEN deficient breast tumoursBergholz JS*, Wang Q*, Wang Q*, Ramseier M, Prakadan S, Fang R, Kabraji S, Gray K, Abell-Hart K, Xie S, Guo X, Von T, Jiang T, Freeman G, Kim HJ, Shalek AK, Roberts TM, Zhao JJ. Nature. 2023 May;617(7959):139-146. doi: 10.1038/s41586-023-05940-w. PMID: 37076617. PMCID: PMC10494520. *: Contributed equally
https://pubmed.ncbi.nlm.nih.gov/37076617/

 

STING Agonism Reprograms Tumor-associated Macrophages and Overcomes Resistance to PARP inhibition in BRCA1-deficient Models of Breast Cancer

STING Agonism Reprograms Tumor associated Macrophages and Overcomes Resistance to PARP inhibition in BRCA1 deficient Models of Breast CancerWang Q*, Bergholz JS*, Ding L, Lin Z, Kabraji SK, Hughes ME, He X, Xie S, Jiang T, Wang W, Zoeller JJ, Kim HJ, Roberts TM, Konstantinopoulos PA, Matulonis UA, Dillon DA, Winer EP, Lin NU, Zhao JJ. Nat Commun. 2022 May 31;13(1):3022. doi:10.1038/s41467-022-30568-1. PMID: 35641483; PMCID: PMC9156717. *: Contributed equally
https://pubmed.ncbi.nlm.nih.gov/35641483/

Targeting Oncogenic KRAS with Molecular Brush-Conjugated Antisense Oligonucleotides

Targeting Oncogenic KRAS with Molecular Brush Conjugated Antisense OligonucleotidesWang D*, Wang Q*, Wang Y, Chen P, Lu X, Jia F, Sun Y, Sun T, Zhang L, Che F, He J, Lian L, Morano G, Shen M, Ren M, Dong SS, Zhao JJ, Zhang K. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29): e2113180119. doi: 10.1073/pnas.2113180119. PMID: 35858356; PMCID: PMC9304022. *: Contributed equally
https://pubmed.ncbi.nlm.nih.gov/35858356/

 

PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer

PARP-Inhibition-Elicits-STING-Dependent-Antitumor Immunity in Brca1 Deficient Ovarian CancerDing L*, Kim HJ*, Wang Q*, Kearns M, Jiang T, Ohlson CE, Li BB, Xie S, Liu JF, Stover EH, Howitt BE, Bronson RT, Lazo S, Roberts TM, Freeman GJ, Konstantinopoulos PA, Matulonis UA, Zhao JJ. Cell Rep. 2018 Dec 11;25(11):2972-2980.e5. doi: 10.1016/j.celrep.2018.11.054. PMID: 30540933; PMCID: PMC6366450. *: Contributed equally
https://pubmed.ncbi.nlm.nih.gov/30540933/

 

Receptor-Interacting Protein Kinase 3 Contributes to Abdominal Aortic Aneurysms via Smooth Muscle Cell Necrosis and Inflammation.

Receptor Interacting-Protein Kinase 3 Contributes to Abdominal Aortic Aneurysms via Smooth Muscle Cell-Necrosis and InflammationWang Q, Liu Z, Ren J, Morgan S, Assa C, Liu B. Circ Res. 2015 Feb 13;116(4):600-11. doi: 10.1161/CIRCRESAHA.116.304899. PMID: 25563840; PMCID: PMC4329096.
https://pubmed.ncbi.nlm.nih.gov/25563840/

 

 

 

Complete List of Published Work in MyBibliography:
https://www.ncbi.nlm.nih.gov/myncbi/qiwei.wang.1/bibliography/public/