Publications

Wenker, I. C., Boscia, A. R., Lewis, C., Tariq, A., Miralles, R., Hanflink, J. C., . . . Patel, M. K. (2022). Forebrain epileptiform activity is not required for seizure-induced apnea in a mouse model of Scn8a epilepsy. FRONTIERS IN NEURAL CIRCUITS, 16. doi:10.3389/fncir.2022.1002013

Thompson, J. A., Miralles, R. M., Wengert, E. R., Wagley, P. K., Yu, W., Wenker, I. C., & Patel, M. K. (2022). Astrocyte reactivity in a mouse model of SCN8A epileptic encephalopathy. EPILEPSIA OPEN, 7(2), 280-292. doi:10.1002/epi4.12564

Wenker, I. C., Wagley, P. K., Boscia, A. R., Lewis, C., & Patel, M. K. (2022). Opto- and Chemogenetic Dissection of Ictal Apnea Neural Circuitry.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36 Suppl 1. doi:10.1096/fasebj.2022.36.s1.r2354

Wenker, I. C., Blizzard, E. A., Wagley, P. K., & Patel, M. K. (2022). Peri-Ictal Autonomic Control of Cardiac Function and Seizure-Induced Death. FRONTIERS IN NEUROSCIENCE, 15. doi:10.3389/fnins.2021.795145

Wengert, E. R., Wagley, P. K., Strohm, S. M., Reza, N., Wenker, I. C., Gaykema, R. P., . . . Patel, M. K. (2022). Targeted Augmentation of Nuclear Gene Output (TANGO) of Scn1a rescues parvalbumin interneuron excitability and reduces seizures in a mouse model of Dravet Syndrome. BRAIN RESEARCH, 1775. doi:10.1016/j.brainres.2021.147743

Wengert, E. R., Miralles, R. M., Wedgwood, K. C. A., Wagley, P. K., Strohm, S. M., Panchal, P. S., . . . Patel, M. K. (2021). Somatostatin-Positive Interneurons Contribute to Seizures in SCN8A Epileptic Encephalopathy. JOURNAL OF NEUROSCIENCE, 41(44), 9257-9273. doi:10.1523/JNEUROSCI.0718-21.2021

Wenker, I. C., Teran, F. A., Wengert, E. R., Wagley, P. K., Panchal, P. S., Blizzard, E. A., . . . Patel, M. K. (2021). Postictal Death Is Associated with Tonic Phase Apnea in a Mouse Model of Sudden Unexpected Death in Epilepsy. ANNALS OF NEUROLOGY, 89(5), 1023-1035. doi:10.1002/ana.26053

Wengert, E. R., Wenker, I. C., Wagner, E. L., Wagley, P. K., Gaykema, R. P., Shin, J. -B., & Patel, M. K. (2021). Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of SCN8A Encephalopathy. FRONTIERS IN NEUROSCIENCE, 15. doi:10.3389/fnins.2021.581048

Guyenet, P. G., Bayliss, D. A., Stornetta, R. L., Kanbar, R., Shi, Y., Holloway, B. B., . . . Wenker, I. C. (2018). Interdependent feedback regulation of breathing by the carotid bodies and the retrotrapezoid nucleus. JOURNAL OF PHYSIOLOGY-LONDON, 596(15), 3029-3042. doi:10.1113/JP274357

Wenker, I. C., Abe, C., Viar, K. E., Stornetta, D. S., Stornetta, R. L., & Guyenet, P. G. (2017). Blood Pressure Regulation by the Rostral Ventrolateral Medulla in Conscious Rats: Effects of Hypoxia, Hypercapnia, Baroreceptor Denervation, and Anesthesia. JOURNAL OF NEUROSCIENCE, 37(17), 4565-4583. doi:10.1523/JNEUROSCI.3922-16.2017

Hawkins, V. E., Takakura, A. C., Trinh, A., Malheiros-Lima, M. R., Cleary, C. M., Wenker, I. C., . . . Mulkey, D. K. (2017). Purinergic regulation of vascular tone in the retrotrapezoid nucleus is specialized to support the drive to breathe. ELIFE, 6. doi:10.7554/eLife.25232

Guyenet, P. G., Bayliss, D. A., Stornetta, R. L., Ludwig, M. -G., Kumar, N. N., Shi, Y., . . . Wenker, I. C. (2016). Proton detection and breathing regulation by the retrotrapezoid nucleus. JOURNAL OF PHYSIOLOGY-LONDON, 594(6), 1529-1551. doi:10.1113/JP271480

Wenker, I., Inglis, M., Guyenet, P., & Stornetta, R. (2015). NPY is Co-localized with TH in Ventrolateral Medullary Neurons Projecting to the Hypothalamus in Mice. In FASEB JOURNAL Vol. 29. Retrieved from https://www.webofscience.com/

Moreira, T. S., Wenker, I. C., Sobrinho, C. R., Barna, B. F., Takakura, A. C., & Mulkey, D. K. (2015). Independent purinergic mechanisms of central and peripheral chemoreception in the rostral ventrolateral medulla. JOURNAL OF PHYSIOLOGY-LONDON, 593(5), 1067-1074. doi:10.1113/jphysiol.2014.284430

Bassi, M., Furuya, W. I., Menani, J. V., Colombari, D. S. A., do Carmo, J. M., da Silva, A. A., . . . Colombari, E. (2014). Leptin into the ventrolateral medulla facilitates chemorespiratory response in leptin-deficient (ob/ob) mice. ACTA PHYSIOLOGICA, 211(1), 240-248. doi:10.1111/apha.12257

Sobrinho, C. R., Wenker, I. C., Poss, E. M., Takakura, A. C., Moreira, T. S., & Mulkey, D. K. (2014). Purinergic signalling contributes to chemoreception in the retrotrapezoid nucleus but not the nucleus of the solitary tract or medullary raphe. JOURNAL OF PHYSIOLOGY-LONDON, 592(6), 1309-1323. doi:10.1113/jphysiol.2013.268490

Wenker, I. C., Sobrinho, C. R., Takakura, A. C., Mulkey, D. K., & Moreira, T. S. (2013). P2Y1 Receptors Expressed by C1 Neurons Determine Peripheral Chemoreceptor Modulation of Breathing, Sympathetic Activity, and Blood Pressure. HYPERTENSION, 62(2), 263-273. doi:10.1161/HYPERTENSIONAHA.113.01487

Hawryluk, J. M., Moreira, T. S., Takakura, A. C., Wenker, I. C., Tzingounis, A. V., & Mulkey, D. K. (2012). KCNQ Channels Determine Serotonergic Modulation of Ventral Surface Chemoreceptors and Respiratory Drive. JOURNAL OF NEUROSCIENCE, 32(47), 16943-16952. doi:10.1523/JNEUROSCI.3043-12.2012

Wenker, I. C., Sobrinho, C. R., Takakura, A. C., Moreira, T. S., & Mulkey, D. K. (2012). Regulation of ventral surface CO2/H+-sensitive neurons by purinergic signalling. JOURNAL OF PHYSIOLOGY-LONDON, 590(9), 2137-2150. doi:10.1113/jphysiol.2012.229666

Wenker, I. C., Benoit, J. P., Chen, X., Liu, H., Horner, R. L., & Mulkey, D. K. (2012). Nitric oxide activates hypoglossal motoneurons by cGMP-dependent inhibition of TASK channels and cGMP-independent activation of HCN channels. JOURNAL OF NEUROPHYSIOLOGY, 107(5), 1489-1499. doi:10.1152/jn.00827.2011

Mulkey, D. K., & Wenker, I. C. (2011). Astrocyte chemoreceptors: mechanisms of H+ sensing by astrocytes in the retrotrapezoid nucleus and their possible contribution to respiratory drive. In EXPERIMENTAL PHYSIOLOGY Vol. 96 (pp. 400-406). doi:10.1113/expphysiol.2010.053140

Wenker, I. C., Kreneisz, O., Nishiyama, A., & Mulkey, D. K. (2010). Astrocytes in the Retrotrapezoid Nucleus Sense H+ by Inhibition of a Kir4.1-Kir5.1-Like Current and May Contribute to Chemoreception by a Purinergic Mechanism. JOURNAL OF NEUROPHYSIOLOGY, 104(6), 3042-3052. doi:10.1152/jn.00544.2010

Wenker, I. (2010). An Active Role for Astrocytes in Synaptic Plasticity?. JOURNAL OF NEUROPHYSIOLOGY, 104(3), 1216-1218. doi:10.1152/jn.00429.2010

Mulkey, D. K., Wenker, I. C., & Kreneisz, O. (2010). Current ideas on central chemoreception by neurons and glial cells in the retrotrapezoid nucleus. JOURNAL OF APPLIED PHYSIOLOGY, 108(5), 1433-1439. doi:10.1152/japplphysiol.01240.2009

McCarthy, M. C., Moncrief, H., Sands, J. M., Markert, R. J., Hall, L. C., Wenker, I. C., . . . Tchorz, K. M. (2009). Neurologic outcomes with cerebral oxygen monitoring in traumatic brain injury. SURGERY, 146(4), 585-591. doi:10.1016/j.surg.2009.06.059