Michael G. Brown
Primary AppointmentProfessor, Medicine: Nephrology
- BS, Biochemistry, VA Tech, Blacksburg, VA
- PhD, Immunology, Medical College of Virginia, VCU, Richmond, VA
NK Cells and Viral Immunity
Immunology, Molecular Biology and Genetics
Research in the Brown Laboratory is centered on molecular and cellular mechanisms of innate immunity and antiviral host defenses. We have applied classical genetic analysis strategies to examine how genetic diversity affects host virus resistance or susceptibility traits in common laboratory strains of mice. Major alleles that contribute to strain-dependent differences in virus resistance and/or immune responsiveness will undoubtedly enhance our understanding of the immune system, which could also lead to identification of new and beneficial targets of immune therapy. Two major research project areas established in the lab are detailed below.
Virus Immunity Research: