Gomez, R. Ariel

R. Ariel Gomez

R. Ariel Gomez

Primary Appointment

Professor, Pediatrics: Nephrology

Contact Information

therefore marking the cells' lineage. The results indicate that in addition to JG cells
Charlottesville, VA 22908
Telephone: 4-3606
Email: rg@virginia.edu
Website: tubular epithelial

Research Interests

Ontogeny of renin-angiotensis system, differentiation of the JG cell.

Research Description



Renin-synthesizing cells are crucial in the regulation of blood pressure and fluid and electrolyte homeostasis. These cells have been considered as terminally differentiated because they synthesize a hormone, are few in numbers, and their restricted juxtaglomerular (JG) localization. However, during embryonic development, and kidney morphogenesis, renin cells are widely distributed and do not become circumscribed to a classical" JG localization until later in postnatal life. In addition