Professor, Biomedical Engineering
- PhD, Bioengineering, University of California, San Diego
Bioinformatics and Genomics, Biomedical Engineering, Biophysics, Biotechnology, Cardiovascular Biology, Computational Biology, Experimental Pathology, Infectious Diseases/Biodefense, Metabolism, Microbiology, Physiology, Structural Biology
Systems biology, infectious disease, cancer, toxicology, metabolic engineering
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there is a pressing need for reconstructing and analyzing the biochemical networks that direct cellular processes. The subsequent analysis of these networks requires high-performance computing and sophisticated mathematical techniques.
Our research goals consist of the construction and analysis of large-scale biochemical networks and their application to human disease. Currently, we are working to develop methods for incorporating high-throughput data with network reconstructions, and we are using these tools to study fundamental problems in infectious disease, cancer, toxicology, and metabolic engineering.