Recent Selected Publications (2018-2023)

pubmedicon30-30Liyayi IK, Forehand AL, Ray JC, Criss AK. Pearl: Metal piracy by Neisseria gonorrhoeae to overcome human nutritional immunity. Accepted 12/30/22, PLOS Pathogens (D-22-01944).

pubmedicon30-30Crawford MA, Ward AE, Gray V, Bailer P, Fisher DJ, Kubicka E, Cui Z, Luo Q, Gray MC, Criss AK, Lum LG, Tamm LK, Letteri RA, Hughes MA#. Disparate regions of the human chemokine CXCL10 exhibit broad-spectrum antimicrobial activity against biodefense and antibiotic-resistant bacterial pathogens. ACS Infectious Diseases 9(1):122-139, 2023.

pubmedicon30-30Werner LM, Alcott A, Mohlin F, Ray JC, Belcher Dufrisne, M, Smirnov A, Columbus L, Blom AM, Criss AK. Neisseria gonorrhoeae co-opts C4b-binding protein to enhance complement-independent survival from neutrophils. bioRxiv December 9, 2022.

pubmedicon30-30Potter AD, Baiocco CM, Papin JA, Criss AK. Transcriptome guided metabolic network analysis reveals rearrangements of carbon flux distribution in Neisseria gonorrhoeae during neutrophil co-culture. bioRxiv December 20, 2022.

pubmedicon30-30Smirnov A, Daily KP, Gray MC, Werner LM, Ragland SA, Johnson MB, Eby JC, Hewlett EL, Taylor RP, Criss AK. Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils. bioRxiv September 2, 2022.

pubmedicon30-30Alcott AM, Werner LM, Baiocco CM, Belcher Dufrisne M, Columbus L, Criss AK. Variable Expression of Opa Proteins by Neisseria gonorrhoeae Influences Bacterial Association and Phagocytic Killing by Human Neutrophils. Journal of Bacteriology 204(4):e0003522, 2022.

pubmedicon30-30Ray JC, Smirnov A, Maurakis SA, Harrison SA, Ke E, Chazin WJ, Cornelissen CN, Criss AK. Adherence Enables Neisseria gonorrhoeae to Overcome Zinc Limitation Imposed by Nutritional Immunity Proteins. Infection and Immunity 90(3):e0000922, 2022.

pubmedicon30-30Edwards VL, Potter AD, D’Mello A, Gray MC, Shetty AC, Zhao X, Hill KM, Ragland SA, Criss AK, Tettelin H. Dual species transcriptomics reveals core metabolic and immunologic processes in the interaction between primary human neutrophils and Neisseria gonorrhoeae strains. bioRxiv doi: 10.1101/2022.02.28.482360, 2022.

pubmedicon30-30Criss AK, Genco CA, Gray-Owen SD, Jerse AE, Seifert HS. Challenges and Controversies Concerning Neisseria gonorrhoeae-Neutrophil Interactions in Pathogenesis. mBio doi: 10.1128/mBio.00721-21,  2021.

cytometry journal cover october 2020Werner LM, Palmer A, Smirnov A, Dufrisne M, Columbus L, Criss AK. Imaging flow cytometry analysis of CEACAM binding to Opa-expressing Neisseria gonorrhoeae. Cytometry: Part A 97:1081-1089, 2020.

pubmedicon30-30Ragland SA, Gray MC, Melson EM, Kendall MM, Criss AK. The effect of lipidation on the localization and activity of a lysozyme inhibitor in Neisseria gonorrhoeae. Journal of Bacteriology 202, doi: 10.1128/JB.00633-19, 2020.

neutrophil journal cover 2020Smirnov A, Solga M, Lannigan J, Criss AK. Using Imaging Flow Cytometry to Quantify Neutrophil Phagocytosis.  Neutrophil Methods and Protocols, series Methods in Molecular Biology, volume 2087, 127-140, ed. Mark T. Quinn and Frank DeLeo, SpringerNature. 2020.


Maurakis S, Keller K, Maxwell CN, Pereira K, Chazin WJ, Criss AK, Cornelissen CN. The Novel Interaction Between Neisseria gonorrhoeae TdfJ and Human S100A7 Allows Gonococci to Subvert Host Zinc Restriction. PLOS Pathogens 15(8):e1007937, 2019.

pubmedicon30-30Criss AK, Allen LM. Cell intrinsic functions of neutrophils and their manipulation by pathogens. Current Opinion in Immunology 60: 124-129, 2019.

pubmedicon30-30Kuhn J, Smirnov A, Criss AK, Columbus L. Quantifying CEACAM targeted liposome delivery using imaging flow cytometry. Molecular Pharmaceutics 16: 2354-2363, 2019.


Handing JW, Ragland SA, Bharathan UV, Criss AK. The MtrCDE Efflux Pump Contributes to Survival of Neisseria gonorrhoeae From Human Neutrophils and Their Antimicrobial Components. Frontiers in Microbiology 9: 2688, 2018.


Palmer A, Criss AK. Gonococcal Defenses against Antimicrobial Activities of Neutrophils. Trends in Microbiology 26: 1022-1034, 2018.

pubmedicon30-30Stevens JS, Gray MC, Morisseau C, Criss AK. Stevens JS, Gray MC, Morisseau C, Criss AK. Endocervical and neutrophil lipoxygenases coordinate neutrophil transepithelial migration to Neisseria gonorrhoeae. The Journal of Infectious Diseases 218: 1663-1674, 2018.

pubmedicon30-30Ragland SA, Humbert MV, Christodoulides M, Criss AK. Neisseria gonorrhoeae employs two protein inhibitors to evade killing by human lysozyme. PLOS Pathogens 14:e1007080, 2018 (doi: 10.1371/journal.ppat.1007080), 2018.

pubmedicon30-30Stevens JS, Criss AK. Pathogenesis of Neisseria gonorrhoeae in the female reproductive tract: neutrophilic host response, sustained infection, and clinical sequelae. Current Opinion in Hematology 25:13-21, 2018.

pubmedicon30-30Ragland SA, Criss AK. From bacterial killing to immune modulation: recent insights into the functions of lysozyme. PLOS Pathogens 13(9):e1006512 (doi:10.1371/journal.ppat.1006512), 2017.