Christopher C. Moore

Brown, N., da Silva, C., Webb, C., Matias, D., Dias, B., Cancio, B., . . . Guler, J. L. (2024). Antimalarial resistance risk in Mozambique detected by a novel quadruplex droplet digital PCR assay. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 68(7). doi:10.1128/aac.00346-24

Gwaikolo, C., Bodo, B., Nabawanuka, D., Mukiibi, M., Seremba, E., Muyinda, P., . . . Ssekitoleko, R. (2024). Impact of supportive supervision visits on the availability of World Health Organization infection prevention and control core components in health facilities in Southwestern Uganda. INFECTION PREVENTION IN PRACTICE, 6(2). doi:10.1016/j.infpip.2024.100355

Chang, B. H., Adakun, S. A., Auma, M. A., Banura, P., Majwala, A., Mbonde, A. A., . . . Moore, C. C. (2024). Outcomes of World Health Organization-defined Severe Respiratory Distress without Shock in Adults in Sub-Saharan Africa. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 209(1), 109-112. doi:10.1164/rccm.202304-0684LE

Qiu, J., Zimmet, A. N., Bell, T. D., Gadrey, S., Brandberg, J., Maldonado, S., . . . Moore, C. C. (2024). Pathophysiological Responses to Bloodstream Infection in Critically Ill Transplant Recipients Compared With Non-Transplant Recipients. CLINICAL INFECTIOUS DISEASES, 78(4), 1011-1021. doi:10.1093/cid/ciad662

Gulleen, E. A., Holte, S., Zhang, Y., Mbarusha, I., Mubiru, D., Pedun, B., . . . Phipps, W. (2023). Etiology of Fever and Associated Outcomes Among Adults Receiving Chemotherapy for the Treatment of Solid Tumors in Uganda. OPEN FORUM INFECTIOUS DISEASES, 10(11). doi:10.1093/ofid/ofad508

Luther, V. P., Barsoumian, A. E., Konold, V. J. L., Vijayan, T., Balba, G., Benson, C., . . . Chirch, L. M. (2023). Inclusion, Diversity, Access, and Equity in Infectious Diseases Fellowship Training: Tools for Program Directors. OPEN FORUM INFECTIOUS DISEASES, 10(6). doi:10.1093/ofid/ofad289

Keim-Malpass, J., Heysell, S. K., Thomas, T. A., Lobo, J. M., Mpagama, S. G., Muzoora, C., & Moore, C. C. (2023). Decision Analytic Modeling for Global Clinical Trial Planning: A Case for HIV-Positive Patients at High Risk for Mycobacterium tuberculosis Sepsis in Uganda.. International journal of environmental research and public health, 20(6), 5041. doi:10.3390/ijerph20065041

Grundy, B. S., Parikh, H., Jacob, S., Banura, P., Moore, C. C., Liu, J., & Houpt, E. R. (2023). Pathogen Detection Using Metagenomic Next-Generation Sequencing of Plasma Samples from Patients with Sepsis in Uganda. MICROBIOLOGY SPECTRUM, 11(1). doi:10.1128/spectrum.04312-22

Gadrey, S. M., Mohanty, P., Haughey, S. P., Jacobsen, B. A., Dubester, K. J., Webb, K. M., . . . Moorman, J. R. (2023). Overt and Occult Hypoxemia in Patients Hospitalized With COVID-19. CRITICAL CARE EXPLORATIONS, 5(1). doi:10.1097/CCE.0000000000000825

Monfredi, O. J., Moore, C. C., Sullivan, B. A., Keim-Malpass, J., Fairchild, K. D., Loftus, T. J., . . . Clermont, G. (2023). Continuous ECG monitoring should be the heart of bedside AI-based predictive analytics monitoring for early detection of clinical deterioration. JOURNAL OF ELECTROCARDIOLOGY, 76, 35-38. doi:10.1016/j.jelectrocard.2022.10.011

Gadrey, S. M., Mohanty, P., Haughey, S. P., Jacobsen, B. A., Dubester, K. J., Webb, K. M., . . . Moorman, J. R. (2022). Overt and occult hypoxemia in patients hospitalized with novel coronavirus disease 2019.. medRxiv. doi:10.1101/2022.06.14.22276166

Said, B., Nuwagira, E., Liyoyo, A., Arinaitwe, R., Gitige, C., Mushagara, R., . . . Mpagama, S. G. (2022). Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial. BMJ OPEN, 12(6). doi:10.1136/bmjopen-2022-061953

Ssekitoleko, R., Seremba, E., Waiswa, F., Nabawanuka, D., Muyinda, P., Okware, S., . . . Moore, C. C. (2022). Availability of the core components of the World Health Organization infection prevention and control strategies in health facilities in Southwestern Uganda: Implications for control of COVID-19. INFECTION PREVENTION IN PRACTICE, 4(2). doi:10.1016/j.infpip.2022.100206

Hazard, R., Bagenda, D., Patterson, A. J., Hoffman, J. T., Lisco, S. J., Urayeneza, O., . . . Moore, C. C. (2022). Performance of the Universal Vital Assessment (UVA) mortality risk score in hospitalized adults with infection in Rwanda: A retrospective external validation study. PLOS ONE, 17(3). doi:10.1371/journal.pone.0265713

Rao, P. S., Moore, C. C., Mbonde, A. A., Nuwagira, E., Orikiriza, P., Nyehangane, D., . . . Muzoora, C. (2021). Population Pharmacokinetics and Significant Under-Dosing of Anti-Tuberculosis Medications in People with HIV and Critical Illness. ANTIBIOTICS-BASEL, 10(6). doi:10.3390/antibiotics10060739

Gulleen, E. A., Adams, S. V., Chang, B. H., Falk, L., Hazard, R., Kabukye, J., . . . Moore, C. C. (2021). Factors and Outcomes Related to the Use of Guideline-Recommended Antibiotics in Patients With Neutropenic Fever at the Uganda Cancer Institute. OPEN FORUM INFECTIOUS DISEASES, 8(7). doi:10.1093/ofid/ofab307

Aryee, J. N. A., Akinleye, S. D., Ugwu-Oju, O. C., Moore, C. C., & Freilich, A. M. (2021). A Series of Nontuberculous Mycobacterial Flexor Tenosynovitis Infections and Cost of Treatment. JOURNAL OF WRIST SURGERY, 10(06), 511-515. doi:10.1055/s-0041-1728801

Liu, S., Huckaby, A. C., Brown, A. C., Moore, C. C., Burbulis, I., McConnell, M. J., & Guler, J. L. (2021). Single-cell sequencing of the small and AT-skewed genome of malaria parasites. GENOME MEDICINE, 13(1). doi:10.1186/s13073-021-00889-9

Kassaza, K., Long, A. C., McDaniels, J. M., Andre, M., Fredrickson, W., Nyehangane, D., . . . Boum, Y. I. I. (2021). Surveillance of Plasmodium falciparum pfcrt haplotypes in southwestern uganda by high-resolution melt analysis. MALARIA JOURNAL, 20(1). doi:10.1186/s12936-021-03657-7

Dueck, N. P., Epstein, S., Franquet, T., Moore, C. C., & Bueno, J. (2021). Atypical Pneumonia: Definition, Causes, and Imaging Features. RADIOGRAPHICS, 41(3), 720-741. doi:10.1148/rg.2021200131

Gulleen, E. A., Ameko, M. K., Ainsworth, J. E., Barnes, L. E., & Moore, C. C. (2020). Predictive Models of Fever, ICU Transfer, and Mortality in Hospitalized Patients With Neutropenia.. Critical care explorations, 2(12), e0289. doi:10.1097/cce.0000000000000289

Zimmet, A. N., Clark, M. T., Gadrey, S. M., Bell, T. D., Zimmet, A. M., Moorman, J. R., & Moore, C. C. (2020). Pathophysiologic Signatures of Bloodstream Infection in Critically Ill Adults.. Critical care explorations, 2(10), e0191. doi:10.1097/cce.0000000000000191

Gadrey, S. M., Clay, R., Zimmet, A. N., Lawson, A. S., Oliver, S. F., Richardson, E. D., . . . Moorman, J. R. (2020). The Relationship Between Acuity of Organ Failure and Predictive Validity of Sepsis-3 Criteria.. Critical care explorations, 2(10), e0199. doi:10.1097/cce.0000000000000199

Brown, A. C., Moore, C. C., & Guler, J. L. (2020). Cholesterol-dependent enrichment of understudied erythrocytic stages of human Plasmodium parasites. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-61392-6

Gadrey, S. M., Lau, C. E., Clay, R., Rhodes, G. T., Lake, D. E., Moore, C. C., . . . Moorman, J. R. (2019). Imputation of partial pressures of arterial oxygen using oximetry and its impact on sepsis diagnosis. PHYSIOLOGICAL MEASUREMENT, 40(11). doi:10.1088/1361-6579/ab5154

Hazard, R. H., Kagina, P., Kitayimbwa, R., Male, K., McShane, M., Mubiru, D., . . . Abdallah, A. (2019). Effect of Empiric Anti-Mycobacterium tuberculosis Therapy on Survival Among Human Immunodeficiency Virus-Infected Adults Admitted With Sepsis to a Regional Referral Hospital in Uganda. OPEN FORUM INFECTIOUS DISEASES, 6(4). doi:10.1093/ofid/ofz140

Byashalira, K., Mbelele, P., Semvua, H., Chilongola, J., Semvua, S., Liyoyo, A., . . . Mpagama, S. (2019). Clinical outcomes of new algorithm for diagnosis and treatment of Tuberculosis sepsis in HIV patients. INTERNATIONAL JOURNAL OF MYCOBACTERIOLOGY, 8(4), 313-319. doi:10.4103/ijmy.ijmy_135_19

Okello, S., Abeya, F. C., Lumori, B. A. E., Akello, S. J., Moore, C. C., Annex, B. H., & Buda, A. J. (2018). Validation of heart failure quality of life tool and usage to predict all-cause mortality in acute heart failure in Uganda: the Mbarara heart failure registry (MAHFER). BMC CARDIOVASCULAR DISORDERS, 18. doi:10.1186/s12872-018-0959-1

Moore, C. C., Jacob, S. T., Banura, P., Zhang, J., Stroup, S., Boulware, D. R., . . . Liu, J. (2019). Etiology of Sepsis in Uganda Using a Quantitative Polymerase Chain Reaction-based TaqMan Array Card. CLINICAL INFECTIOUS DISEASES, 68(2), 266-272. doi:10.1093/cid/ciy472

Kassaza, K., Operario, D. J., Nyehangane, D., Coffey, K. C., Namugosa, M., Turkheimer, L., . . . Boum, Y. I. I. (2018). Detection of Plasmodium Species by High-Resolution Melt Analysis of DNA from Blood Smears Acquired in Southwestern Uganda. JOURNAL OF CLINICAL MICROBIOLOGY, 56(1). doi:10.1128/JCM.01060-17

Hadeed, M. M., MacDonell, J. R., Dempsey, I. J., Moore, C. C., & Browne, J. A. (2017). Chronic Nocardia cyriacigeorgica Periprosthetic Knee Infection Successfully Treated with a Two-Stage Revision: A Case Report.. JBJS case connector, 7(4), e74. doi:10.2106/jbjs.cc.16.00250

Amir, A., Saulters, K. J., Muhindo, R., & Moore, C. C. (2017). Fluid resuscitation of patients with severe infection in Uganda: less is more. JOURNAL OF CRITICAL CARE, 42, 348-349. doi:10.1016/j.jcrc.2017.08.041

Amir, A., Saulters, K. J., Muhindo, R., & Moore, C. C. (2017). Outcomes of patients with severe infection in Uganda according to adherence to the World Health Organization's Integrated Management of Adolescent and Adult Illness fluid resuscitation guidelines. JOURNAL OF CRITICAL CARE, 41, 24-28. doi:10.1016/j.jcrc.2017.04.042

Pholwat, S., Liu, J., Stroup, S., Jacob, S. T., Banura, P., Moore, C. C., . . . Guler, J. L. (2017). The Malaria TaqMan Array Card Includes 87 Assays for Plasmodium falciparum Drug Resistance, Identification of Species, and Genotyping in a Single Reaction. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 61(5). doi:10.1128/AAC.00110-17

Gulleen, E., Ameko, M., Ainsworth, J., Rayapati, P., Barnes, L., & Moore, C. (2017). Predictive Models of Fever and Adverse Outcomes in Hospitalized Patients with Neutropenia. Open Forum Infectious Diseases, 4(suppl_1), S698. doi:10.1093/ofid/ofx163.1873

Moore, C. C., Hazard, R., Saulters, K. J., Ainsworth, J., Adakun, S. A., Amir, A., . . . Barnes, L. E. (2017). Derivation and validation of a universal vital assessment (UVA) score: a tool for predicting mortality in adult hospitalised patients in sub-Saharan Africa. BMJ GLOBAL HEALTH, 2(2). doi:10.1136/bmjgh-2017-000344

Amir, A., Saulters, K. J., Olum, S., Pitts, K., Parsons, A., Churchill, C., . . . Moore, C. C. (2016). Outcomes of patients with severe sepsis after the first 6 hours of resuscitation at a regional referral hospital in Uganda. JOURNAL OF CRITICAL CARE, 33, 78-83. doi:10.1016/j.jcrc.2016.01.023

Redko, C., Bessong, P., Burt, D., Luna, M., Maling, S., Moore, C., . . . Dillingham, R. (2016). Exploring the Significance of Bidirectional Learning for Global Health Education. ANNALS OF GLOBAL HEALTH, 82(6), 955-963. doi:10.1016/j.aogh.2016.11.008

Liu, J., Ochieng, C., Wiersma, S., Stroeher, U., Towner, J. S., Whitmer, S., . . . Fields, B. (2016). Development of a TaqMan Array Card for Acute-Febrile-Illness Outbreak Investigation and Surveillance of Emerging Pathogens, Including Ebola Virus. JOURNAL OF CLINICAL MICROBIOLOGY, 54(1), 49-58. doi:10.1128/JCM.02257-15

MacLean, I. S., Day, S. R., Moore, C. C., & Browne, J. A. (2015). Blastomycosis infection of the knee treated with staged total knee arthroplasty. KNEE, 22(6), 669-671. doi:10.1016/j.knee.2015.03.003

Evans, E. E., Wang, X. -Q., & Moore, C. C. (2016). Distance from care predicts in-hospital mortality in HIV-infected patients with severe sepsis from rural and semi-rural Virginia, USA. INTERNATIONAL JOURNAL OF STD & AIDS, 27(5), 370-376. doi:10.1177/0956462415584489

Orikiriza, P., Tibenderana, B., Siedner, M. J., Mueller, Y., Byarugaba, F., Moore, C. C., . . . Boum, Y. I. I. (2015). Low Resistance to First and Second Line Anti-Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda. PLOS ONE, 10(2). doi:10.1371/journal.pone.0118191

Okello, S., Millard, A., Owori, R., Asiimwe, S. B., Siedner, M. J., Rwebembera, J., . . . Annex, B. H. (2014). Prevalence of lower extremity Peripheral artery disease among adult diabetes patients in Southwestern Uganda. BMC CARDIOVASCULAR DISORDERS, 14. doi:10.1186/1471-2261-14-75

Asiimwe, S. B., Muzoora, C., Wilson, L. A., & Moore, C. C. (2015). Bedside measures of malnutrition and association with mortality in hospitalized adults. CLINICAL NUTRITION, 34(2), 252-256. doi:10.1016/j.clnu.2014.03.013

Day, S. R., Weiss, D. B., Hazen, K. C., & Moore, C. C. (2014). Successful treatment of osseous blastomycosis without pulmonary or disseminated disease and review of the literature. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 79(2), 242-244. doi:10.1016/j.diagmicrobio.2014.02.021

Asiimwe, S. B., Okello, S., & Moore, C. C. (2014). Frequency of Vital Signs Monitoring and its Association with Mortality among Adults with Severe Sepsis Admitted to a General Medical Ward in Uganda. PLOS ONE, 9(2). doi:10.1371/journal.pone.0089879

Musie, E., Moore, C. C., Martin, E. N., & Scheld, W. M. (2014). Toll-Like Receptor 4 Stimulation before or after Streptococcus pneumoniae Induced Sepsis Improves Survival and Is Dependent on T-Cells. PLOS ONE, 9(1). doi:10.1371/journal.pone.0086015

Das, R., Koo, M. -S., Kim, B. H., Jacob, S. T., Subbian, S., Yao, J., . . . Bucala, R. (2013). Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 110(32), E2997-E3006. doi:10.1073/pnas.1301128110

Auma, M. A., Siedner, M. J., Nyehangane, D., Nalusaji, A., Nakaye, M., Mwanga-Amumpaire, J., . . . Moore, C. C. (2013). Malaria is an uncommon cause of adult sepsis in south-western Uganda. MALARIA JOURNAL, 12. doi:10.1186/1475-2875-12-146

Jacob, S. T., Lim, M., Banura, P., Bhagwanjee, S., Bion, J., Cheng, A. C., . . . West, T. E. (2013). Integrating sepsis management recommendations into clinical care guidelines for district hospitals in resource-limited settings: the necessity to augment new guidelines with future research. BMC MEDICINE, 11. doi:10.1186/1741-7015-11-107

Okello, S., Millard, A. S., Rwebembera, J., Wilson, T., Moore, C. C., & Annex, B. H. (2013). A GENERAL REPORT OF THE PREVALENCE AND CORRELATES OF PERIPHERAL ARTERIAL DISEASE IN SOUTHWESTERN UGANDA. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 61(10), E1411. doi:10.1016/S0735-1097(13)61411-4

Majwala, A., Burke, R., Patterson, W., Pinkerton, R., Muzoora, C., Wilson, L. A., & Moore, C. C. (2013). Handheld Point-of-Care Cerebrospinal Fluid Lactate Testing Predicts Bacterial Meningitis in Uganda. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 88(1), 127-131. doi:10.4269/ajtmh.2012.12-0447

Jacob, S. T., Banura, P., Baeten, J. M., Moore, C. C., Meya, D., Nakiyingi, L., . . . Scheid, W. M. (2012). The impact of early monitored management on survival in hospitalized adult Ugandan patients with severe sepsis: A prospective intervention study. CRITICAL CARE MEDICINE, 40(7), 2050-2058. doi:10.1097/CCM.0b013e31824e65d7

Nguyen, T. H., Nguyen, T. H. T., Nguyen, A. T., Nguyen, T. K., Moore, C. C., Doan, T. N. D., & Hirayama, K. (2012). Performance of Thirteen Clinical Rules to Distinguish Bacterial and Presumed Viral Meningitis in Vietnamese Children. PLOS ONE, 7(11). doi:10.1371/journal.pone.0050341

Doka, N. I., Jacob, S. T., Banura, P., Moore, C. C., Meya, D., Mayanja-Kizza, H., . . . Yuan, W. (2012). Enrichment of HIV-1 Subtype AD Recombinants in a Ugandan Cohort of Severely Septic Patients. PLOS ONE, 7(10). doi:10.1371/journal.pone.0048356

Keller, S. A., Moore, C. C., Clemens, M. G., McKillop, I. H., & Huynh, T. (2011). Activated protein C restores hepatic microcirculation during sepsis by modulating vasoregulator expression.. Shock (Augusta, Ga.), 36(4), 361-369. doi:10.1097/shk.0b013e31822c7380

Ssekitoleko, R., Pinkerton, R., Muhindo, R., Bhagani, S., & Moore, C. C. (2011). Aggregate Evaluable Organ Dysfunction Predicts In-Hospital Mortality from Sepsis in Uganda. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 85(4), 697-702. doi:10.4269/ajtmh.2011.10-0692

Ssekitoleko, R., Jacob, S. T., Banura, P., Pinkerton, R., Meya, D. B., Reynolds, S. J., . . . Moore, C. C. (2011). Hypoglycemia at admission is associated with inhospital mortality in Ugandan patients with severe sepsis. CRITICAL CARE MEDICINE, 39(10), 2271-2276. doi:10.1097/CCM.0b013e3182227bd2

Pawlowski, S. W., Moore, C. C., & Wispelwey, B. (2011). Persistent Hiccups Due to Fixed-Dose Tenofovir and Emtricitabine. Infectious Diseases in Clinical Practice, 19(5), 354-356. doi:10.1097/ipc.0b013e3181f5eab1

Keller, S. A., Moore, C. C., Evans, S. L., McKillop, I. H., & Huynh, T. (2011). Activated protein C alters inflammation and protects renal function in sepsis.. The Journal of surgical research, 168(1), e103-e109. doi:10.1016/j.jss.2011.01.008