Josyf (Joe) C. Mychaleckyj

Jones, A. C., Patki, A., Srinivasasainagendra, V., Tiwari, H. K., Armstrong, N. D., Chaudhary, N. S., . . . Irvin, M. R. (2024). Single-Ancestry versus Multi-Ancestry Polygenic Risk Scores for CKD in Black American Populations.. Journal of the American Society of Nephrology : JASN. doi:10.1681/asn.0000000000000437

Mychaleckyj, J. C., Normeshie, C., Keene, K. L., & Hauck, F. R. (2024). Organ weights and length anthropometry measures at autopsy for sudden infant death syndrome cases and other infant deaths in the Chicago infant mortality study. AMERICAN JOURNAL OF HUMAN BIOLOGY. doi:10.1002/ajhb.24126

Dubin, R. F., Deo, R., Ren, Y., Wang, J., Pico, A. R., Mychaleckyj, J. C., . . . Ganz, P. (2024). Incident heart failure in chronic kidney disease: proteomics informs biology and risk stratification. EUROPEAN HEART JOURNAL. doi:10.1093/eurheartj/ehae288

Scholz, M., Horn, K., Pott, J., Wuttke, M., Kuehnapfel, A., Nasr, M. K., . . . Pattaro, C. (2024). X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. NATURE COMMUNICATIONS, 15(1). doi:10.1038/s41467-024-44709-1

Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., . . . Auer, P. L. (2023). Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing. NATURE GENETICS, 55(11), 1912-+. doi:10.1038/s41588-023-01553-1

Miller, R. G., Mychaleckyj, J. C., Onengut-Gumuscu, S., Feingold, E., Orchard, T. J., & Costacou, T. (2023). DNA methylation and 28-year cardiovascular disease risk in type 1 diabetes: the Epidemiology of Diabetes Complications (EDC) cohort study. CLINICAL EPIGENETICS, 15(1). doi:10.1186/s13148-023-01539-0

Kudtarkar, P., Costanzo, M. C., Sun, Y., Jang, D., Koesterer, R., Mychaleckyj, J. C., . . . Burtt, N. P. (2023). Leveraging type 1 diabetes human genetic and genomic data in the T1D knowledge portal. PLOS BIOLOGY, 21(8). doi:10.1371/journal.pbio.3002233

Shabani, M., Wang, M., Jenkins, G. D., Rotter, J. I., Rich, S. S., Batzler, A., . . . Pereira, N. L. (2023). Myocardial Fibrosis and Cardiomyopathy Risk: A Genetic Link in the MESA. CIRCULATION-HEART FAILURE, 16(9), 818-828. doi:10.1161/CIRCHEARTFAILURE.122.010262

Leiser, C. L., Whitsel, E. A., Reiner, A., Rich, S. S., Rotter, J. I., Taylor, K. D., . . . Kaufman, J. D. (2023). Associations between Ambient Air Pollutants and Clonal Hematopoiesis of Indeterminate Potential. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 32(10), 1470-1473. doi:10.1158/1055-9965.EPI-23-0305

Oldham, J. M., Allen, R. J., Lorenzo-Salazar, J. M., Molyneaux, P. L., Ma, S. -F., Joseph, C., . . . Noth, I. (2023). PCSK6 and Survival in Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 207(11), 1515-1524. doi:10.1164/rccm.202205-0845OC

Wong, W. J., Emdin, C., Bick, A. G., Zekavat, S. M., Niroula, A., Pirruccello, J. P., . . . Zoellner, S. (2023). Clonal haematopoiesis and risk of chronic liver disease. NATURE, 616(7958). doi:10.1038/s41586-023-05857-4

Weinstock, J. S., Gopakumar, J., Burugula, B. B., Uddin, M. M., Jahn, N., Belk, J. A., . . . Jaiswal, S. (2023). Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis. NATURE, 616(7958), 755-+. doi:10.1038/s41586-023-05806-1

Kudtarkar, P., Costanzo, M. C., Sun, Y., Jang, D., Koesterer, R., Mychaleckyj, J. C., . . . Burtt, N. P. (2023). Leveraging type 1 diabetes human genetic and genomic data in the T1D Knowledge Portal.. bioRxiv. doi:10.1101/2023.02.03.526066

Miller, R. G., Mychaleckyj, J. C., Onengut-Gumuscu, S., Orchard, T. J., & Costacou, T. (2023). TXNIP DNA methylation is associated with glycemic control over 28 years in type 1 diabetes: findings from the Pittsburgh Epidemiology of Diabetes Complications (EDC) study. BMJ OPEN DIABETES RESEARCH & CARE, 11(1). doi:10.1136/bmjdrc-2022-003068

Pan, Y., Sun, X., Mi, X., Huang, Z., Hsu, Y., Hixson, J. E., . . . Kelly, T. N. (2023). Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease. HUMAN MOLECULAR GENETICS, 32(6), 1048-1060. doi:10.1093/hmg/ddac290

Durda, P., Raffield, L. M., Lange, E. M., Olson, N. C., Jenny, N. S., Cushman, M., . . . Lange, L. A. (2022). Circulating Soluble CD163, Associations With Cardiovascular Outcomes and Mortality, and Identification of Genetic Variants in Older Individuals: The Cardiovascular Health Study. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 11(21). doi:10.1161/JAHA.121.024374

Sano, S., Horitani, K., Ogawa, H., Halvardson, J., Chavkin, N. W., Wang, Y., . . . Walsh, K. (2022). Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality. SCIENCE, 377(6603), 292-297. doi:10.1126/science.abn3100

Gorski, M., Rasheed, H., Teumer, A., Thomas, L. F., Graham, S. E., Sveinbjornsson, G., . . . Heid, I. M. (2022). Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies. KIDNEY INTERNATIONAL, 102(3), 624-639. doi:10.1016/j.kint.2022.05.021

Winkler, T. W., Rasheed, H., Teumer, A., Gorski, M., Rowan, B. X., Stanzick, K. J., . . . Heid, I. M. (2022). Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals. COMMUNICATIONS BIOLOGY, 5(1). doi:10.1038/s42003-022-03448-z

Lee, B., Kader, M. A., Colgate, E. R., Carmolli, M., Dickson, D. M., Diehl, S. A., . . . Kirkpatrick, B. D. (2021). Oral rotavirus vaccine shedding as a marker of mucosal immunity. SCIENTIFIC REPORTS, 11(1). doi:10.1038/s41598-021-01288-1

McDonough, C. W., Warren, H. R., Jack, J. R., Motsinger-Reif, A. A., Armstrong, N. D., Bis, J. C., . . . Cooper-DeHoff, R. M. (2021). Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies. CLINICAL PHARMACOLOGY & THERAPEUTICS, 110(3), 723-732. doi:10.1002/cpt.2355

Seplyarskiy, V. B., Soldatov, R. A., Koch, E., McGinty, R. J., Goldmann, J. M., Hernandez, R. D., . . . Sunyaev, S. (2021). Population sequencing data reveal a compendium of mutational processes in the human germ line. SCIENCE, 373(6558), 1030-+. doi:10.1126/science.aba7408

Mychaleckyj, J. C., Valo, E., Ichimura, T., Ahluwalia, T. S., Dina, C., Miller, R. G., . . . Krolewski, A. S. (2021). Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 32(10), 2634-2651. doi:10.1681/ASN.2020101457

Zimmerman, K. D., Schurr, T. G., Chen, W. -M., Nayak, U., Mychaleckyj, J. C., Quet, Q., . . . Ramos, P. S. (2021). Genetic landscape of Gullah African Americans. AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, 175(4), 905-919. doi:10.1002/ajpa.24333

Breeze, C. E., Batorsky, A., Lee, M. K., Szeto, M. D., Xu, X., McCartney, D. L., . . . Franceschini, N. (2021). Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci. GENOME MEDICINE, 13(1). doi:10.1186/s13073-021-00877-z

Natarajan, P., Pampana, A., Graham, S. E., Ruotsalainen, S. E., Perry, J. A., de Vries, P. S., . . . Kuopio, T. (2021). Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-22339-1

Lin, B. M., Grinde, K. E., Brody, J. A., Breeze, C. E., Raffield, L. M., Mychaleckyj, J. C., . . . Franceschini, N. (2021). Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. EBIOMEDICINE, 63. doi:10.1016/j.ebiom.2020.103157

Gorski, M., Jung, B., Li, Y., Matias-Garcia, P. R., Wuttke, M., Coassin, S., . . . Heid, I. M. (2021). Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. KIDNEY INTERNATIONAL, 99(4), 926-939. doi:10.1016/j.kint.2020.09.030

Bick, A. G., Weinstock, J. S., Nandakumar, S. K., Fulco, C. P., Bao, E. L., Zekavat, S. M., . . . Natarajan, P. (2021). Inherited causes of clonal haematopoiesis in 97,691 whole genomes (vol 586, pg 763, 2020). NATURE, 591(7849), E27. doi:10.1038/s41586-021-03280-1

Chen, T. K., Katz, R., Estrella, M. M., Post, W. S., Kramer, H., Rotter, J. I., . . . Peralta, C. A. (2020). Association of APOL1 Genotypes With Measures of Microvascular and Endothelial Function, and Blood Pressure in MESA. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 9(17). doi:10.1161/JAHA.120.017039

Li, X., Li, Z., Zhou, H., Gaynor, S. M., Liu, Y., Chen, H., . . . Lin, X. (2020). Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. NATURE GENETICS, 52(9), 969-+. doi:10.1038/s41588-020-0676-4

Williams, F. B., Kader, A., Colgate, E. R., Dickson, D. M., Carmolli, M., Uddin, M. I., . . . Lee, B. (2021). Maternal Secretor Status Affects Oral Rotavirus Vaccine Response in Breastfed Infants in Bangladesh. JOURNAL OF INFECTIOUS DISEASES, 224(7), 1147-1151. doi:10.1093/infdis/jiaa101

Wojcik, G. L., Korpe, P., Marie, C., Mentzer, A. J., Carstensen, T., Mychaleckyj, J., . . . Duggal, P. (2020). Genome-Wide Association Study of Cryptosporidiosis in Infants Implicates PRKCA. MBIO, 11(1). doi:10.1128/mBio.03343-19

Morieri, M. L., Shah, H. S., Sjaarda, J., Lenzini, P. A., Campbell, H., Motsinger-Reif, A. A., . . . Doria, A. (2020). PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid. DIABETES, 69(4), 771-783. doi:10.2337/db19-0973

Biancolin, A. D., Martchenko, A., Mitova, E., Gurges, P., Michalchyshyn, E., Chalmers, J. A., . . . Brubaker, P. L. (2020). The core clock gene, Bmal1, and its downstream target, the SNARE regulatory protein secretagogin, are necessary for circadian secretion of glucagon-like peptide-1. MOLECULAR METABOLISM, 31, 124-137. doi:10.1016/j.molmet.2019.11.004

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., . . . Wilson, J. F. (2019). Associations of autozygosity with a broad range of human phenotypes. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-12283-6

Kachroo, P., Hecker, J., Chawes, B. L., Ahluwalia, T. S., Cho, M. H., Qiao, D., . . . Zoellner, S. (2019). Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma. CHEST, 156(6), 1068-1079. doi:10.1016/j.chest.2019.08.2202

Teumer, A., Li, Y., Ghasemi, S., Prins, B. P., Wuttke, M., Hermle, T., . . . Koettgen, A. (2019). Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-019-11576-0

Mychaleckyj, J. C., Zhang, D., Nayak, U., Colgate, E. R., Carmolli, M., Dickson, D., . . . Petri, W. A. J. (2020). Association of breast milk gamma-linolenic acid with infant anthropometric outcomes in urban, low-income Bangladeshi families: a prospective, birth cohort study. EUROPEAN JOURNAL OF CLINICAL NUTRITION, 74(5), 698-707. doi:10.1038/s41430-019-0498-6

Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., . . . Pattaro, C. (2019). A catalog of genetic loci associated with kidney function from analyses of a million individuals. NATURE GENETICS, 51(6), 957-+. doi:10.1038/s41588-019-0407-x

Tang, Y., Lenzini, P. A., Pop-Busui, R., Ray, P. R., Campbell, H., Perkins, B. A., . . . Doria, A. (2019). A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies. DIABETES, 68(8), 1649-1662. doi:10.2337/db19-0109

Guan, M., Keaton, J. M., Dimitrov, L., Hicks, P. J., Xu, J., Palmer, N. D., . . . Spielman, R. (2019). Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. HUMAN GENOMICS, 13. doi:10.1186/s40246-019-0205-7

Morris, A. P., Le, T. H., Wu, H., Akbarov, A., van der Most, P. J., Hemani, G., . . . Franceschini, N. (2019). Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies. NATURE COMMUNICATIONS, 10. doi:10.1038/s41467-018-07867-7

Skupien, J., Smiles, A. M., Valo, E., Ahluwalia, T. S., Gyorgy, B., Sandholm, N., . . . Krolewski, A. S. (2019). Variations in Risk of End-Stage Renal Disease and Risk of Mortality in an International Study of Patients With Type 1 Diabetes and Advanced Nephropathy. DIABETES CARE, 42(1), 93-101. doi:10.2337/dc18-1369

Mottl, A. K., Buse, J. B., Ismail-Beigi, F., Sigal, R. J., Pedley, C. F., Papademetriou, V., . . . Craven, T. E. (2018). Long-Term Effects of Intensive Glycemic and Blood Pressure Control and Fenofibrate Use on Kidney Outcomes. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 13(11), 1693-1702. doi:10.2215/CJN.06200518

Morieri, M. L., Gao, H., Pigeyre, M., Shah, H. S., Sjaarda, J., Mendonca, C., . . . Doria, A. (2018). Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial. DIABETES CARE, 41(11), 2404-2413. doi:10.2337/dc18-0709

Wojcik, G. L., Marie, C., Abhyankar, M. M., Yoshida, N., Watanabe, K., Mentzer, A. J., . . . Duggal, P. (2018). Genome-Wide Association Study Reveals Genetic Link between Diarrhea-Associated Entamoeba histolytica Infection and Inflammatory Bowel Disease. MBIO, 9(5). doi:10.1128/mBio.01668-18

Rotroff, D. M., Pijut, S. S., Marvel, S. W., Jack, J. R., Havener, T. M., Pujol, A., . . . ACCORD/ACCORDion Investigators. (2018). Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.. Clinical pharmacology and therapeutics, 103(4), 712-721. doi:10.1002/cpt.798

Mychaleckyj, J. C., Nayak, U., Colgate, E. R., Zhang, D., Carstensen, T., Ahmed, S., . . . Petri, W. A. J. (2018). Multiplex genomewide association analysis of breast milk fatty acid composition extends the phenotypic association and potential selection of FADS1 variants to arachidonic acid, a critical infant micronutrient. JOURNAL OF MEDICAL GENETICS, 55(7), 459-468. doi:10.1136/jmedgenet-2017-105134

Lee, B., Carmolli, M., Dickson, D. M., Colgate, E. R., Diehl, S. A., Uddin, M. I., . . . Kirkpatrick, B. D. (2018). Rotavirus-Specific Immunoglobulin A Responses Are Impaired and Serve as a Suboptimal Correlate of Protection Among Infants in Bangladesh. CLINICAL INFECTIOUS DISEASES, 67(2), 186-192. doi:10.1093/cid/ciy076

Lee, B., Dickson, D. M., deCamp, A. C., Colgate, E. R., Diehl, S. A., Uddin, M. I., . . . Kirkpatrick, B. D. (2018). Histo-Blood Group Antigen Phenotype Determines Susceptibility to Genotype-Specific Rotavirus Infections and Impacts Measures of Rotavirus Vaccine Efficacy. JOURNAL OF INFECTIOUS DISEASES, 217(9), 1399-1407. doi:10.1093/infdis/jiy054

Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., . . . London, S. J. (n.d.). Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome Open Research, 3, 4. doi:10.12688/wellcomeopenres.12583.2

Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., . . . London, S. J. (2018). Meta-analysis of exome array data identifies six novel genetic loci for lung function.. Wellcome open research, 3, 4. doi:10.12688/wellcomeopenres.12583.3

Shah, H. S., Morieri, M. L., Marcovina, S. M., Sigal, R. J., Gerstein, H. C., Wagner, M. J., . . . Doria, A. (2018). Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD. DIABETES CARE, 41(2), 348-355. doi:10.2337/dc17-1638

Ashar, F. N., Zhang, Y., Longchamps, R. J., Lane, J., Moes, A., Grove, M. L., . . . Arking, D. E. (2017). Association of Mitochondrial DNA Copy Number With Cardiovascular Disease. JAMA CARDIOLOGY, 2(11), 1247-1255. doi:10.1001/jamacardio.2017.3683

Nayak, U., Kanungo, S., Zhang, D., Colgate, E. R., Carmolli, M. P., Dey, A., . . . Mychaleckyj, J. C. (2017). Influence of maternal and socioeconomic factors on breast milk fatty acid composition in urban, low-income families. MATERNAL AND CHILD NUTRITION, 13(4). doi:10.1111/mcn.12423

Mychaleckyj, J. C., Havt, A., Nayak, U., Pinkerton, R., Farber, E., Concannon, P., . . . Guerrant, R. L. (2017). Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions. MOLECULAR BIOLOGY AND EVOLUTION, 34(3), 559-574. doi:10.1093/molbev/msw249

Shah, H. S., Gao, H., Morieri, M. L., Skupien, J., Marvel, S., Pare, G., . . . Doria, A. (2016). Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial. DIABETES CARE, 39(11), 1915-1924. doi:10.2337/dc16-0285

Colgate, E. R., Haque, R., Dickson, D. M., Carmolli, M. P., Mychaleckyj, J. C., Nayak, U., . . . Kirkpatrick, B. D. (2016). Delayed Dosing of Oral Rotavirus Vaccine Demonstrates Decreased Risk of Rotavirus Gastroenteritis Associated With Serum Zinc: A Randomized Controlled Trial. CLINICAL INFECTIOUS DISEASES, 63(5), 634-641. doi:10.1093/cid/ciw346

van Leeuwen, E. M., Sabo, A., Bis, J. C., Huffman, J. E., Manichaikul, A., Smith, A. V., . . . van Duijn, C. M. (2016). Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels. JOURNAL OF MEDICAL GENETICS, 53(7), 441-449. doi:10.1136/jmedgenet-2015-103439

Lins Ponte, P. R., Quintela Soares de Medeiros, P. H., Havt, A., Caetano, J. A., Cid, D. A. C., Gondim Prata, M. D. M., . . . Moreira Lima, A. A. (2016). Clinical evaluation, biochemistry and genetic polymorphism analysis for the diagnosis of lactose intolerance in a population from northeastern Brazil. CLINICS, 71(2), 82-89. doi:10.6061/clinics/2016(02)06

Mychaleckyj, J. C., Haque, R., Carmolli, M., Zhang, D., Colgate, E. R., Nayak, U., . . . Petri, W. A. J. (2016). Effect of substituting IPV for tOPV on immunity to poliovirus in Bangladeshi infants: An open-label randomized controlled trial. VACCINE, 34(3), 358-366. doi:10.1016/j.vaccine.2015.11.046

Kirkpatrick, B. D., & Mychaleckyj, J. C. (2015). Polio eradication: inching forward, with safety nets.. The Lancet. Infectious diseases, 15(11), 1244-1245. doi:10.1016/s1473-3099(15)00261-3

Naylor, C., Lu, M., Haque, R., Mondal, D., Buonomo, E., Nayak, U., . . . Petri, W. A. J. (2015). Environmental Enteropathy, Oral Vaccine Failure and Growth Faltering in Infants in Bangladesh. EBIOMEDICINE, 2(11), 1759-1766. doi:10.1016/j.ebiom.2015.09.036

Durda, P., Sabourin, J., Lange, E. M., Nalls, M. A., Mychaleckyj, J. C., Jenny, N. S., . . . Lange, L. A. (2015). Plasma Levels of Soluble Interleukin-2 Receptor a Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 35(10), 2246-2253. doi:10.1161/ATVBAHA.115.305289

Caramori, M. L., Kim, Y., Natarajan, R., Moore, J. H., Rich, S. S., Mychaleckyj, J. C., . . . Mauer, M. (2015). Differential Response to High Glucose in Skin Fibroblasts of Monozygotic Twins Discordant for Type 1 Diabetes. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 100(6), E883-E889. doi:10.1210/jc.2014-4467

Caramori, M. L., Kim, Y., Goldfine, A. B., Moore, J. H., Rich, S. S., Mychaleckyj, J. C., . . . Mauer, M. (2015). Differential Gene Expression in Diabetic Nephropathy in Individuals With Type 1 Diabetes. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 100(6), E876-E882. doi:10.1210/jc.2014-4465

van Leeuwen, E. M., Karssen, L. C., Deelen, J., Isaacs, A., Medina-Gomez, C., Mbarek, H., . . . van Duijn, C. M. (2015). Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. NATURE COMMUNICATIONS, 6. doi:10.1038/ncomms7065

Onengut-Gumuscu, S., Chen, W. -M., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., . . . Rich, S. S. (2015). Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. NATURE GENETICS, 47(4), 381-U199. doi:10.1038/ng.3245

Kirkpatrick, B. D., Colgate, E. R., Mychaleckyj, J. C., Hague, R., Dickson, D. M., Carmolli, M. P., . . . Petri, W. A. J. (2015). The "Performance of Rotavirus and Oral Polio Vaccines in Developing Countries" (PROVIDE) Study: Description of Methods of an Interventional Study Designed to Explore Complex Biologic Problems. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 92(4), 744-751. doi:10.4269/ajtmh.14-0518

van Leeuwen, E. M., Huffman, J. E., Bis, J. C., Isaacs, A., Mulder, M., Sabo, A., . . . van Duijn, C. (2015). Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. NPJ AGING AND MECHANISMS OF DISEASE, 1. doi:10.1038/npjamd.2015.11

O'Connor, T. D., Fu, W., Turner, E., Mychaleckyj, J. C., Logsdon, B., Auer, P., . . . Akey, J. M. (2015). Rare Variation Facilitates Inferences of Fine-Scale Population Structure in Humans. MOLECULAR BIOLOGY AND EVOLUTION, 32(3), 653-660. doi:10.1093/molbev/msu326

Ng, M. C. Y., Shriner, D., Chen, B. H., Li, J., Chen, W. -M., Guo, X., . . . Bowden, D. W. (2014). Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes. PLOS GENETICS, 10(8). doi:10.1371/journal.pgen.1004517

Tomlinson, M. J., Pitsillides, A., Pickin, R., Mika, M., Keene, K. L., Hou, X., . . . Onengut-Gumuscu, S. (2014). Fine Mapping and Functional Studies of Risk Variants for Type 1 Diabetes at Chromosome 16p13.13. DIABETES, 63(12), 4360-4368. doi:10.2337/db13-1785

Skupien, J., Warram, J. H., Niewczas, M. A., Gohda, T., Malecki, M., Mychaleckyj, J. C., . . . Krolewski, A. S. (2014). Synergism Between Circulating Tumor Necrosis Factor Receptor 2 and HbA_1c in Determining Renal Decline During 5-18 Years of Follow-up in Patients With Type 1 Diabetes and Proteinuria. DIABETES CARE, 37(9), 2601-2608. doi:10.2337/dc13-1983

Lange, L. A., Hu, Y., Zhang, H., Xue, C., Schmidt, E. M., Tang, Z. -Z., . . . Willer, C. J. (2014). Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol. AMERICAN JOURNAL OF HUMAN GENETICS, 94(2), 233-245. doi:10.1016/j.ajhg.2014.01.010

Peloso, G. M., Auer, P. L., Bis, J. C., Voorman, A., Morrison, A. C., Stitziel, N. O., . . . Cupples, L. A. (2014). Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks. AMERICAN JOURNAL OF HUMAN GENETICS, 94(2), 223-232. doi:10.1016/j.ajhg.2014.01.009

Keene, K. L., Chen, W. -M., Chen, F., Williams, S. R., Elkhatib, S. D., Hsu, F. -C., . . . Sale, M. M. (2014). Genetic associations with plasma B12, B6, and folate levels in an ischemic stroke population from the Vitamin Intervention for Stroke Prevention (VISP) trial. FRONTIERS IN PUBLIC HEALTH, 2. doi:10.3389/fpubh.2014.00112

Haque, R., Snider, C., Liu, Y., Ma, J. Z., Liu, L., Nayak, U., . . . Petri, W. A. J. (2014). Oral polio vaccine response in breast fed infants with malnutrition and diarrhea. VACCINE, 32(4), 478-482. doi:10.1016/j.vaccine.2013.11.056

Allen, E. K., Chen, W. -M., Weeks, D. E., Chen, F., Hou, X., Mattos, J. L., . . . Sale, M. M. (2013). A Genome-Wide Association Study of Chronic Otitis Media with Effusion and Recurrent Otitis Media Identifies a Novel Susceptibility Locus on Chromosome 2. JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY, 14(6), 791-800. doi:10.1007/s10162-013-0411-2

Monda, K. L., Chen, G. K., Taylor, K. C., Palmer, C., Edwards, T. L., Lange, L. A., . . . Haiman, C. A. (2013). A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. NATURE GENETICS, 45(6), 690-+. doi:10.1038/ng.2608

Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., . . . Gordon, J. I. (2013). Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor. SCIENCE, 339(6119), 548-554. doi:10.1126/science.1229000

Pezzolesi, M. G., Jeong, J., Smiles, A. M., Skupien, J., Mychaleckyj, J. C., Rich, S. S., . . . Krolewski, A. S. (2013). Family-Based Association Analysis Confirms the Role of the Chromosome 9q21.32 Locus in the Susceptibility of Diabetic Nephropathy. PLOS ONE, 8(3). doi:10.1371/journal.pone.0060301

Liu, C. -T., Monda, K. L., Taylor, K. C., Lange, L., Demerath, E. W., Palmas, W., . . . Fox, C. S. (2013). Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci. PLOS GENETICS, 9(8). doi:10.1371/journal.pgen.1003681

Huang, J., Sabater-Lleal, M., Asselbergs, F. W., Tregouet, D., Shin, S. -Y., Ding, J., . . . Hamsten, A. (2012). Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. BLOOD, 120(24), 4873-4881. doi:10.1182/blood-2012-06-436188

Bonds, D. E., Craven, T. E., Buse, J., Crouse, J. R., Cuddihy, R., Elam, M., . . . Sperl-Hillen, J. -A. (2012). Fenofibrate-associated changes in renal function and relationship to clinical outcomes among individuals with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) experience. DIABETOLOGIA, 55(6), 1641-1650. doi:10.1007/s00125-012-2524-2

Mychaleckyj, J. C., Craven, T., Nayak, U., Buse, J., Crouse, J. R., Elam, M., . . . Ginsberg, H. N. (2012). Reversibility of Fenofibrate Therapy-Induced Renal Function Impairment in ACCORD Type 2 Diabetic Participants. DIABETES CARE, 35(5), 1008-1014. doi:10.2337/dc11-1811

Cheng, Y. -C., Anderson, C. D., Bione, S., Keene, K., Maguire, J. M., Nalls, M., . . . Mitchell, B. D. (2012). Are Myocardial Infarction-Associated Single-Nucleotide Polymorphisms Associated With Ischemic Stroke?. STROKE, 43(4), 980-U143. doi:10.1161/STROKEAHA.111.632075

Caramori, M. L., Kim, Y., Moore, J. H., Rich, S. S., Mychaleckyj, J. C., Kikyo, N., & Mauer, M. (2012). Gene Expression Differences in Skin Fibroblasts in Identical Twins Discordant for Type 1 Diabetes. DIABETES, 61(3), 739-744. doi:10.2337/db11-0617

Manichaikul, A., Palmas, W., Rodriguez, C. J., Peralta, C. A., Divers, J., Guo, X., . . . Mychaleckyj, J. C. (2012). Population Structure of Hispanics in the United States: The Multi-Ethnic Study of Atherosclerosis. PLOS GENETICS, 8(4), 285-298. doi:10.1371/journal.pgen.1002640

Hsu, F. -C., Sides, E. G., Mychaleckyj, J. C., Worrall, B. B., Elias, G. A., Liu, Y., . . . Sale, M. M. (2011). Transcobalamin 2 variant associated with poststroke homocysteine modifies recurrent stroke risk. NEUROLOGY, 77(16), 1543-1550. doi:10.1212/WNL.0b013e318233b1f9

Chen, W. -M., Allen, E. K., Mychaleckyj, J. C., Chen, F., Hou, X., Rich, S. S., . . . Sale, M. M. (2011). Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM). BMC MEDICAL GENETICS, 12. doi:10.1186/1471-2350-12-124

Bhatia, G., Patterson, N., Pasaniuc, B., Zaitlen, N., Genovese, G., Pollack, S., . . . Price, A. L. (2011). Genome-wide Comparison of African-Ancestry Populations from CARe and Other Cohorts Reveals Signals of Natural Selection. AMERICAN JOURNAL OF HUMAN GENETICS, 89(3), 368-381. doi:10.1016/j.ajhg.2011.07.025

Upadhya, S. C., Smith, T. K., Brennan, P. A., Mychaleckyj, J. C., & Hegde, A. N. (2011). Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice. NEUROCHEMISTRY INTERNATIONAL, 59(6), 787-803. doi:10.1016/j.neuint.2011.08.009

Keene, K. L., Quinlan, A. R., Hou, X., Hall, I. M., Mychaleckyj, J. C., Onengut-Gumuscu, S., & Concannon, P. (2012). Evidence for two independent associations with type 1 diabetes at the 12q13 locus. GENES AND IMMUNITY, 13(1), 66-70. doi:10.1038/gene.2011.56

Manichaikul, A., Chen, W. -M., Williams, K., Wong, Q., Sale, M. M., Pankow, J. S., . . . Mychaleckyj, J. C. (2012). Analysis of family- and population-based samples in cohort genome-wide association studies. HUMAN GENETICS, 131(2), 275-287. doi:10.1007/s00439-011-1071-0

Mychaleckyj, J. C., Farber, E. A., Chmielewski, J., Artale, J., Light, L. S., Bowden, D. W., . . . Marcovina, S. M. (2011). Buffy coat specimens remain viable as a DNA source for highly multiplexed genome-wide genetic tests after long term storage. JOURNAL OF TRANSLATIONAL MEDICINE, 9. doi:10.1186/1479-5876-9-91

Pezzolesi, M. G., Poznik, G. D., Skupien, J., Smiles, A. M., Mychaleckyj, J. C., Rich, S. S., . . . Krolewski, A. S. (2011). An intergenic region on chromosome 13q33.3 is associated with the susceptibility to kidney disease in type 1 and 2 diabetes. KIDNEY INTERNATIONAL, 80(1), 105-111. doi:10.1038/ki.2011.64

Böger, C. A., Chen, M. -H., Tin, A., Olden, M., Köttgen, A., de Boer, I. H., . . . Kao, W. H. L. (2011). CUBN is a gene locus for albuminuria.. Journal of the American Society of Nephrology : JASN, 22(3), 555-570. doi:10.1681/asn.2010060598

Kure, M., Pezzolesi, M. G., Poznik, G. D., Katavetin, P., Skupien, J., Dunn, J. S., . . . Krolewski, A. S. (2011). Genetic variation in the matrix metalloproteinase genes and diabetic nephropathy in type 1 diabetes. MOLECULAR GENETICS AND METABOLISM, 103(1), 60-65. doi:10.1016/j.ymgme.2011.01.001

Teraoka, S. N., Bernstein, J. L., Reiner, A. S., Haile, R. W., Bernstein, L., Lynch, C. F., . . . Concannon, P. (2011). Single nucleotide polymorphisms associated with risk for contralateral breast cancer in the Women's Environment, Cancer, and Radiation Epidemiology (WECARE) Study. BREAST CANCER RESEARCH, 13(6). doi:10.1186/bcr3057

Sale, M. M., Chen, W. -M., Weeks, D. E., Mychaleckyj, J. C., Hou, X., Marion, M., . . . Daly, K. A. (2011). Evaluation of 15 Functional Candidate Genes for Association with Chronic Otitis Media with Effusion and/or Recurrent Otitis Media (COME/ROM). PLOS ONE, 6(8). doi:10.1371/journal.pone.0022297

Solorzano, G., Chen, F., Mychaleckyj, J. C., Chen, W. -M., Hsu, F. -C., Sale, M., & Worrall, B. B. (2011). Antihypertensive Class And Stroke Recurrence: An Analysis Of The VISP Trial. STROKE, 42(3), E348. Retrieved from https://www.webofscience.com/

Manichaikul, A., Mychaleckyj, J. C., Rich, S. S., Daly, K., Sale, M., & Chen, W. -M. (2010). Robust relationship inference in genome-wide association studies. BIOINFORMATICS, 26(22), 2867-2873. doi:10.1093/bioinformatics/btq559

Noble, J. A., Valdes, A. M., Varney, M. D., Carlson, J. A., Moonsamy, P., Fear, A. L., . . . Erlich, H. A. (2010). HLA Class I and Genetic Susceptibility to Type 1 Diabetes Results From the Type 1 Diabetes Genetics Consortium. DIABETES, 59(11), 2972-2979. doi:10.2337/db10-0699

Varney, M. D., Valdes, A. M., Carlson, J. A., Noble, J. A., Tait, B. D., Bonella, P., . . . Erlich, H. (2010). HLA DPA1, DPB1 Alleles and Haplotypes Contribute to the Risk Associated With Type 1 Diabetes Analysis of the Type 1 Diabetes Genetics Consortium Families. DIABETES, 59(8), 2055-2062. doi:10.2337/db09-0680

Pezzolesi, M. G., Skupien, J., Mychaleckyj, J. C., Warram, J. H., & Krolewski, A. S. (2010). Insights to the Genetics of Diabetic Nephropathy Through a Genome-Wide Association Study of the GoKinD Collection. SEMINARS IN NEPHROLOGY, 30(2), 126-140. doi:10.1016/j.semnephrol.2010.01.004

Leak, T. S., Langefeld, C. D., Keene, K. L., Gallagher, C. J., Lu, L., Mychaleckyj, J. C., . . . Sale, M. M. (2010). Chromosome 7p linkage and association study for diabetes related traits and type 2 diabetes in an African-American population enriched for nephropathy. BMC MEDICAL GENETICS, 11. doi:10.1186/1471-2350-11-22

Mychaleckyj, J. C., Noble, J. A., Moonsamy, P. V., Carlson, J. A., Varney, M. D., Post, J., . . . Erlich, H. A. (2010). HLA genotyping in the international Type 1 Diabetes Genetics Consortium. CLINICAL TRIALS, 7, S75-S87. doi:10.1177/1740774510373494

Patel, R. K., Elias, G. A., Hsu, F. -C., Mychaleckyj, J. C., Chen, W. -M., Worrall, B. B., & Sale, M. M. (2010). Investigation of Recurrent Stroke Risk in the Vitamin Intervention for Stroke Prevention (VISP) Trial Suggests Different Genetic Influences on Prevalent and Incident Stroke. STROKE, 41(4), E335. Retrieved from https://www.webofscience.com/

Elias, G. A., Patel, R. K., Chen, W. -M., Mychaleckyj, J. C., Hsu, F. -C., Worrall, B. B., & Sale, M. M. (2010). Association of a Transcobalamin 2 (TCN2) Variant Located in the 3UTR With Post-stroke Homocysteine Level in Subjects From the Vitamin Intervention for Stroke Prevention Trial. STROKE, 41(4), E335. Retrieved from https://www.webofscience.com/