John Nelson Campbell
Assistant Professor, Biology
485 McCormick Road
Charlottesville, Virginia 22904
Bio & Overview
Academic Information
- Department
- Biology
Primary Education
- BS, Biological Psychology, College of William and Mary, 2002
- PhD, Neuroscience, Virginia Commonwealth University School of Medicine, 2012
Other Affiliations
- MSTP
- BIMS
Research Interests
Research Disciplines
- Computational Biology
- Neuroscience
Research Opportunities
- Bioinformatics & Genomics
- Cellular and Molecular Metabolism
- Computational Biology
- Molecular and Systems Neuroscience
- Neuroscience
PhD Programs
- Neuroscience
Selected Publications
2026
A brain reward circuit inhibited by next-generation weight-loss drugs in mice
Nature. 2026; 654(8120): 1055 - 1064. DOI:10.1038/S41586-026-10444-4.
A High‐Resolution Transcriptomic Atlas of Cell Types in the Ventral Visual Thalamus
Journal of Neurochemistry. 2026; 170(3):. DOI:10.1111/JNC.70406.
A spatial and projection-based transcriptomic atlas of paraventricular hypothalamic cell types
Cell Reports. 2026; 45(2): 116904. DOI:10.1016/J.CELREP.2025.116904.
2025
A novel neuron population that selectively controls metabolism
Physiology. 2025; 40(S1):. DOI:10.1152/PHYSIOL.2025.40.S1.0789.
Cardiac vagal motor neurons
Current Opinion in Neurobiology. 2025; 93: 103068. DOI:10.1016/J.CONB.2025.103068.
Co-Conservation of synaptic gene expression and circuitry in collicular neurons
Nature Communications. 2025; 16(1):. DOI:10.1038/S41467-025-64204-5.
2024
Dorsal motor vagal neurons can elicit bradycardia and reduce anxiety-like behavior
iScience. 2024; 27(3): 109137. DOI:10.1016/J.ISCI.2024.109137.
Ghrelin deletion and conditional ghrelin cell ablation increase pancreatic islet size in mice
Journal of Clinical Investigation. 2024; 134(10):. DOI:10.1172/JCI182168.
Investigating the Role of Arcuate Pirt Neurons in Energy Homeostasis
Physiology. 2024; 39(S1):. DOI:10.1152/PHYSIOL.2024.39.S1.624.
Molecular cell types as functional units of the efferent vagus nerve
Seminars in Cell and Developmental Biology. 2024; 156: 210 - 218. DOI:10.1016/J.SEMCDB.2023.07.007.
Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety
Nature Metabolism. 2024; 6(12): 2354 - 2373. DOI:10.1038/S42255-024-01168-8.
Molecular organization of adrenergic and noradrenergic neurons in the mouse ventrolateral medulla
Physiology. 2024; 39(S1):. DOI:10.1152/PHYSIOL.2024.39.S1.1195.
Molecular Organization of Autonomic, Respiratory, and Spinally-Projecting Neurons in the Mouse Ventrolateral Medulla
Journal of Neuroscience. 2024; 44(31): e2211232024. DOI:10.1523/JNEUROSCI.2211-23.2024.
2023
Disambiguating control of the diving reflex by the nucleus ambiguus
Physiology. 2023; 38(S1):. DOI:10.1152/PHYSIOL.2023.38.S1.5729637.
Dorsal motor vagal neurons can suppress heart rate in mice
Physiology. 2023; 38(S1):. DOI:10.1152/PHYSIOL.2023.38.S1.5793744.
Genetic and Functional Identification of Cardiovagal Nucleus Ambiguus Neurons
Physiology. 2023; 38(S1):. DOI:10.1152/PHYSIOL.2023.38.S1.5732321.
Ghrelin deletion and conditional ghrelin cell ablation increase pancreatic islet size in mice
Journal of Clinical Investigation. 2023; 133(24):. DOI:10.1172/JCI169349.
Leptin receptor neurons in the dorsomedial hypothalamus input to the circadian feeding network
Science Advances. 2023; 9(34):. DOI:10.1126/SCIADV.ADH9570.
Mapping visual functions onto molecular cell types in the mouse superior colliculus
Neuron. 2023; 111(12): 1876 - 1886.e5. DOI:10.1016/J.NEURON.2023.03.036.
2022
1315-P: Optogenetic Activation of Vagal Motor Neurons in Mice Modulates Heart Rate but Not Blood Glucose Levels
Diabetes. 2022; 71(Supplement_1):. DOI:10.2337/DB22-1315-P.
Chemogenetic activation of noradrenergic A5 neurons increases blood pressure and visceral sympathetic activity in adult rats
American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 2022; 323(4): R512 - R531. DOI:10.1152/AJPREGU.00119.2022.
Food-induced dopamine signaling in AgRP neurons promotes feeding
Cell Reports. 2022; 41(9): 111718. DOI:10.1016/J.CELREP.2022.111718.
Genetic encoding of an esophageal motor circuit
Cell Reports. 2022; 39(11): 110962. DOI:10.1016/J.CELREP.2022.110962.
Sonic hedgehog-dependent recruitment of GABAergic interneurons into the developing visual thalamus
eLife. 2022; 11:. DOI:10.7554/ELIFE.79833.
2021
Control of Heart Rate by Nucleus Ambiguus Cardiovagal Neurons
The FASEB Journal. 2021; 35(S1):. DOI:10.1096/FASEBJ.2021.35.S1.02769.
Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits
Nature Human Behaviour. 2021; 6(1): 155 - 163. DOI:10.1038/S41562-021-01182-W.
Highly selective brain-to-gut communication via genetically defined vagus neurons
Neuron. 2021; 109(13): 2106 - 2115.e4. DOI:10.1016/J.NEURON.2021.05.004.
LRP1 regulates food intake and energy balance in GABAergic neurons independently of leptin action
American Journal of Physiology - Endocrinology and Metabolism. 2021; 320(2): E379 - E389. DOI:10.1152/AJPENDO.00399.2020.
2020
Dopamine Signaling in the Suprachiasmatic Nucleus Enables Weight Gain Associated with Hedonic Feeding
Current Biology. 2020; 30(7): 1352 - 1355. DOI:10.1016/J.CUB.2020.03.034.
Dopamine Signaling in the Suprachiasmatic Nucleus Enables Weight Gain Associated with Hedonic Feeding
Current Biology. 2020; 30(2): 196 - 208.e8. DOI:10.1016/J.CUB.2019.11.029.
Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations
Nature Communications. 2020; 11(1):. DOI:10.1038/S41467-020-17197-2.
2019
The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits
Neuron. 2019; 102(3): 653 - 667.e6. DOI:10.1016/J.NEURON.2019.02.028.
2017
A molecular census of arcuate hypothalamus and median eminence cell types
Nature Neuroscience. 2017; 20(3): 484 - 496. DOI:10.1038/NN.4495.
Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling
Neuron. 2017; 96(1): 190 - 206.e7. DOI:10.1016/J.NEURON.2017.09.014.
Erratum: Corrigendum: A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH
Nature Neuroscience. 2017; 20(8): 1189 - 1189. DOI:10.1038/NN0817-1189B.
2016
A Postsynaptic AMPK→p21-Activated Kinase Pathway Drives Fasting-Induced Synaptic Plasticity in AgRP Neurons
Neuron. 2016; 91(1): 25 - 33. DOI:10.1016/J.NEURON.2016.05.025.
Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit
eLife. 2016; 5:. DOI:10.7554/ELIFE.12225.
Dynamic GABAergic afferent modulation of AgRP neurons
Nature Neuroscience. 2016; 19(12): 1628 - 1635. DOI:10.1038/NN.4392.