Jie Sun

Li, C., Qian, W., Wei, X., Narasimhan, H., Wu, Y., Arish, M., . . . Sun, J. (2024). Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae after acute COVID-19.. Science translational medicine, 16(756), eadn0136. doi:10.1126/scitranslmed.adn0136

Nguyen, C., Kudek, M., Zander, R., Niu, H., Shen, J., Bauer, A., . . . Cui, W. (2024). Bhlhe40 Promotes CD4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation during Viral Infection.. Journal of immunology (Baltimore, Md. : 1950), 212(11), 1829-1842. doi:10.4049/jimmunol.2300355

Canderan, G., Muehling, L. M., Kadl, A., Ladd, S., Bonham, C., Cross, C. E., . . . Woodfolk, J. A. (2024). Distinct Type 1 Immune Networks Underlie the Severity of Restrictive Lung Disease after COVID-19.. bioRxiv. doi:10.1101/2024.04.03.587929

Zhu, X., Wu, Y., Li, Y., Zhou, X., Watzlawik, J. O., Chen, Y. M., . . . Zeng, H. (2024). Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1.. Res Sq. doi:10.21203/rs.3.rs-3957355/v1

Zhu, X., Wu, Y., Li, Y., Zhou, X., Watzlawik, J. O., Chen, Y. M., . . . Zeng, H. (2024). The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.. bioRxiv. doi:10.1101/2024.02.26.582122

Ge, J., Shao, H., Ding, H., Huang, Y., Wu, X., Sun, J., & Que, J. (2024). Single Cell Analysis of Lung Lymphatic Endothelial Cells and Lymphatic Responses during Influenza Infection.. Journal of respiratory biology and translational medicine, 1(1), 10003. doi:10.35534/jrbtm.2024.10003

Son, Y. M., Cheon, I. S., Li, C., & Sun, J. (2024). Persistent B Cell-Derived MHC Class II Signaling Is Required for the Optimal Maintenance of Tissue-Resident Helper T Cells.. ImmunoHorizons, 8(2), 163-171. doi:10.4049/immunohorizons.2300093

Guo, K., Yombo, D. J. K., Wang, Z., Navaeiseddighi, Z., Xu, J., Schmit, T., . . . Khan, N. (2024). The chemokine receptor CXCR3 promotes CD8⁺ T cell-dependent lung pathology during influenza pathogenesis. SCIENCE ADVANCES, 10(1). doi:10.1126/sciadv.adj1120

Jie, S., Narasimhan, H., Cheon, I. S., Qian, W., Hu, S., Parimon, T., . . . Chen, P. (2023). Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19. doi:10.21203/rs.3.rs-3587418/v1

Narasimhan, H., Cheon, I. S., Qian, W., Hu, S., Parimon, T., Li, C., . . . Sun, J. (2023). Proximal immune-epithelial progenitor interactions drive chronic tissue sequelae post COVID-19.. bioRxiv. doi:10.1101/2023.09.13.557622

Kasmani, M. Y., Topchyan, P., Brown, A. K., Brown, R. J., Wu, X., Chen, Y., . . . Cui, W. (2023). A spatial sequencing atlas of age-induced changes in the lung during influenza infection. NATURE COMMUNICATIONS, 14(1). doi:10.1038/s41467-023-42021-y

Monroe, J. M., Quach, H. Q., Punia, S., Enninga, E. A. L., Fedyshyn, Y., Girsch, J. H., . . . Chakraborty, R. (2024). Vertical Transmission of SARS-CoV-2-Specific Antibodies and Cytokine Profiles in Pregnancy. JOURNAL OF INFECTIOUS DISEASES, 229(2), 473-484. doi:10.1093/infdis/jiad399

Fain, C. E., Zheng, J., Jin, F., Ayasoufi, K., Wu, Y., Lilley, M. T., . . . Johnson, A. J. (2024). Discrete class I molecules on brain endothelium differentially regulate neuropathology in experimental cerebral malaria. BRAIN, 147(2), 566-589. doi:10.1093/brain/awad319

Wu, Y., Hu, S. S., Zhang, R., Goplen, N. P., Gao, X., Narasimhan, H., . . . Sun, J. (2023). Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages. ISCIENCE, 26(7). doi:10.1016/j.isci.2023.107197

Zhu, B., Wei, X., Narasimhan, H., Qian, W., Zhang, R., Cheon, I. S., . . . Sun, J. (2023). Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19. SCIENCE IMMUNOLOGY, 8(82). doi:10.1126/sciimmunol.adf0348

Cheon, I. S., Son, Y. M., & Sun, J. (2023). Tissue-resident memory T cells and lung immunopathology. IMMUNOLOGICAL REVIEWS, 316(1), 63-83. doi:10.1111/imr.13201

Cable, J., Sun, J., Cheon, I. S., Vaughan, A. E., Castro, I. A., Stein, S. R., . . . Eddens, T. (2023). Respiratory viruses: New frontiers-a Keystone Symposia report. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1522(1), 60-73. doi:10.1111/nyas.14958

Wei, X., Narasimhan, H., Zhu, B., & Sun, J. (2023). Host Recovery from Respiratory Viral Infection. ANNUAL REVIEW OF IMMUNOLOGY, 41, 277-300. doi:10.1146/annurev-immunol-101921-040450

Arish, M., & Sun, J. (2023). Monocyte and macrophage function in respiratory viral infections. ANIMAL DISEASES, 3(1). doi:10.1186/s44149-023-00095-7

Bingham, G. C., Muehling, L. M., Li, C., Huang, Y., Ma, S. -F., Abebayehu, D., . . . Bonham, C. A. (2024). High-dimensional comparison of monocytes and T cells in post-COVID and idiopathic pulmonary fibrosis. FRONTIERS IN IMMUNOLOGY, 14. doi:10.3389/fimmu.2023.1308594

Tang, J., & Sun, J. (2023). Lung tissue-resident memory T cells: the gatekeeper to respiratory viral (re)-infection.. Current opinion in immunology, 80, 102278. doi:10.1016/j.coi.2022.102278

Tang, J., Zeng, C., Cox, T. M., Li, C., Son, Y. M., Cheon, I. S., . . . Sun, J. (2022). Respiratory mucosal immunity against SARS-CoV-2 after mRNA vaccination. SCIENCE IMMUNOLOGY, 7(76). doi:10.1126/sciimmunol.add4853

Huang, H., Fang, Y., Jiang, M., Zhang, Y., Biermann, J., Melms, J. C., . . . Que, J. (2022). Contribution of Trp63^CreERT2-labeled cells to alveolar regeneration is independent of tuft cells. ELIFE, 11. doi:10.7554/eLife.78217

Hajnik, R. L., Plante, J. A., Liang, Y., Alameh, M. -G., Tang, J., Bonam, S. R., . . . Hu, H. (2022). Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models. SCIENCE TRANSLATIONAL MEDICINE, 14(662). doi:10.1126/scitranslmed.abq1945

Arish, M., Qian, W., Narasimhan, H., & Sun, J. (2023). COVID-19 immunopathology: From acute diseases to chronic sequelae. JOURNAL OF MEDICAL VIROLOGY, 95(1). doi:10.1002/jmv.28122

Narasimhan, H., Wu, Y., Goplen, N. P., & Sun, J. (2022). Immune determinants of chronic sequelae after respiratory viral infection. SCIENCE IMMUNOLOGY, 7(73). doi:10.1126/sciimmunol.abm7996

Fu, Y., Pajulas, A., Wang, J., Zhou, B., Cannon, A., Cheung, C. C. L., . . . Kaplan, M. H. (2022). Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9. NATURE COMMUNICATIONS, 13(1). doi:10.1038/s41467-022-31596-7

Ulrich, B. J., Kharwadkar, R., Chu, M., Pajulas, A., Muralidharan, C., Koh, B., . . . Kaplan, M. H. (2022). Allergic airway recall responses require IL-9 from resident memory CD4⁺ T cells. SCIENCE IMMUNOLOGY, 7(69). doi:10.1126/sciimmunol.abg9296

Fu, Y., Wang, J., Zhou, B., Pajulas, A., Gao, H., Ramdas, B., . . . Kaplan, M. H. (2022). An IL-9-pulmonary macrophage axis defines the allergic lung inflammatory environment. SCIENCE IMMUNOLOGY, 7(68). doi:10.1126/sciimmunol.abi9768

Gao, X., Zhu, B., Wu, Y., Li, C., Zhou, X., Tang, J., & Sun, J. (2022). TFAM-Dependent Mitochondrial Metabolism Is Required for Alveolar Macrophage Maintenance and Homeostasis. JOURNAL OF IMMUNOLOGY, 208(6), 1456-1466. doi:10.4049/jimmunol.2100741

Wu, X., Kasmani, M. Y., Zheng, S., Khatun, A., Chen, Y., Winkler, W., . . . Cui, W. (2022). BATF promotes group 2 innate lymphoid cell-mediated lung tissue protection during acute respiratory virus infection. SCIENCE IMMUNOLOGY, 7(67). doi:10.1126/sciimmunol.abc9934

Cheon, I. S., Li, C., Son, Y. M., Goplen, N. P., Wu, Y., Cassmann, T., . . . Sun, J. (2021). Immune signatures underlying post-acute COVID-19 lung sequelae. SCIENCE IMMUNOLOGY, 6(65). doi:10.1126/sciimmunol.abk1741

Zhu, B., Wu, Y., Huang, S., Zhang, R., Son, Y. M., Li, C., . . . Sun, J. (2021). Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. IMMUNITY, 54(6), 1200-+. doi:10.1016/j.immuni.2021.04.001

Son, Y. M., Cheon, I. S., Wu, Y., Li, C., Wang, Z., Gao, X., . . . Sun, J. (2021). Tissue-resident CD4⁺ T helper cells assist the development of protective respiratory B and CD8⁺ T cell memory responses. SCIENCE IMMUNOLOGY, 6(55). doi:10.1126/sciimmunol.abb6852

Goplen, N. P., Cheon, I. S., & Sun, J. (2021). Age-Related Dynamics of Lung-Resident Memory CD8⁺ T Cells in the Age of COVID-19. FRONTIERS IN IMMUNOLOGY, 12. doi:10.3389/fimmu.2021.636118

Goplen, N. P., Wu, Y., Son, Y. M., Li, C., Wang, Z., Cheon, I. S., . . . Sun, J. (2020). Tissue-resident CD8⁺ T cells drive age-associated chronic lung sequelae after viral pneumonia. SCIENCE IMMUNOLOGY, 5(53). doi:10.1126/sciimmunol.abc4557

Fu, Y., Wang, J., Panangipalli, G., Ulrich, B. J., Koh, B., Xu, C., . . . Kaplan, M. H. (2020). STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-020-18648-6

Yang, S., Adaway, M., Du, J., Huang, S., Sun, J., Bidwell, J. P., & Zhou, B. (2021). NMP4 regulates the innate immune response to influenza A virus infection. MUCOSAL IMMUNOLOGY, 14(1), 209-218. doi:10.1038/s41385-020-0280-z

Li, C., Zhu, B., Son, Y. M., Wang, Z., Jiang, L., Xiang, M., . . . Sun, J. (2019). The Transcription Factor Bhlhe40 Programs Mitochondria! Regulation of Resident CD8⁺ T Cell Fitness and Functionality. IMMUNITY, 51(3), 491-+. doi:10.1016/j.immuni.2019.08.013

Wang, Z., Wang, S., Goplen, N. P., Li, C., Cheon, I. S., Dai, Q., . . . Sun, J. (2019). PD-1^hi CD8⁺ resident memory T cells balance immunity and fibrotic sequelae. SCIENCE IMMUNOLOGY, 4(36). doi:10.1126/sciimmunol.aaw1217

Zhu, B., Zhang, R., Li, C., Jiang, L., Xiang, M., Ye, Z., . . . Sun, J. (2019). BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(24), 11888-11893. doi:10.1073/pnas.1902310116

Huang, S., Jiang, L., Cheon, I. S., & Sun, J. (2019). Targeting Peroxisome Proliferator-Activated Receptor-Gamma Decreases Host Mortality After Influenza Infection in Obese Mice. VIRAL IMMUNOLOGY, 32(4), 161-169. doi:10.1089/vim.2019.0016

Huang, S., Zhu, B., Cheon, I. S., Goplen, N. P., Jiang, L., Zhang, R., . . . Sun, J. (2019). PPAR-γ in Macrophages Limits Pulmonary Inflammation and Promotes Host Recovery following Respiratory Viral Infection. JOURNAL OF VIROLOGY, 93(9). doi:10.1128/JVI.00030-19

Gu, D., Lin, H., Zhang, X., Fan, Q., Chen, S., Shahda, S., . . . Xie, J. (2018). Simultaneous Inhibition of MEK and Hh Signaling Reduces Pancreatic Cancer Metastasis. CANCERS, 10(11). doi:10.3390/cancers10110403

Cheon, I. S., Son, Y. M., Jiang, L., Goplen, N. P., Kaplan, M. H., Limper, A. H., . . . Sun, J. (2018). Neonatal hyperoxia promotes asthma-like features through IL-33-dependent ILC2 responses. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 142(4), 1100-1112. doi:10.1016/j.jaci.2017.11.025

Huang, S., Shen, Y., Pham, D., Jiang, L., Wang, Z., Kaplan, M. H., . . . Sun, J. (2017). IRF4 Modulates CD8⁺ T Cell Sensitivity to IL-2 Family Cytokines.. ImmunoHorizons, 1(6), 92-100. doi:10.4049/immunohorizons.1700020

Xie, M. M., Koh, B. -H., Hollister, K., Wu, H., Sun, J., Kaplan, M. H., & Dent, A. L. (2017). Bcl6 promotes follicular helper T-cell differentiation and PD-1 expression in a Blimp1-independent manner in mice. EUROPEAN JOURNAL OF IMMUNOLOGY, 47(7), 1136-1141. doi:10.1002/eji.201747034

Amet, T., Son, Y. M., Jiang, L., Cheon, I. S., Huang, S., Gupta, S. K., . . . Sun, J. (2017). BCL6 represses antiviral resistance in follicular T helper cells. JOURNAL OF LEUKOCYTE BIOLOGY, 102(2), 527-536. doi:10.1189/jlb.4A1216-513RR

Zhang, S., Sun, J., Fang, Y., Nassiri, M., Liu, L., Zhou, J., . . . Vance, G. H. (2017). Signet-ring cell lymphoma: clinicopathologic, immunohistochemical, and fluorescence in situ hybridization studies of 7 cases.. Annals of diagnostic pathology, 26, 38-42. doi:10.1016/j.anndiagpath.2016.10.002

Belle, L., Agle, K., Zhou, V., Yin-Yuan, C., Komorowski, R., Eastwood, D., . . . Drobyski, W. R. (2016). Blockade of interleukin-27 signaling reduces GVHD in mice by augmenting Treg reconstitution and stabilizing Foxp3 expression. BLOOD, 128(16), 2068-2082. doi:10.1182/blood-2016-02-698241

Mehrotra, P., Krishnamurthy, P., Sun, J., Goenka, S., & Kaplan, M. H. (2015). Poly-ADP-ribosyl polymerase-14 promotes T helper 17 and follicular T helper development. IMMUNOLOGY, 146(4), 537-546. doi:10.1111/imm.12515

Tung, C. -Y., Lewis, D. E., Han, L., Jaja, M., Yao, S., Li, F., . . . Chang, H. -C. (2014). Activation of dendritic cell function by soypeptide lunasin as a novel vaccine adjuvant. VACCINE, 32(42), 5411-5419. doi:10.1016/j.vaccine.2014.07.103

Yao, S., Buzo, B. F., Pham, D., Jiang, L., Taparowsky, E. J., Kaplan, M. H., & Sun, J. (2013). Interferon Regulatory Factor 4 Sustains CD8⁺ T Cell Expansion and Effector Differentiation. IMMUNITY, 39(5), 833-845. doi:10.1016/j.immuni.2013.10.007

Jabeen, R., Goswami, R., Awe, O., Kulkarni, A., Nguyen, E. T., Attenasio, A., . . . Kaplan, M. H. (2013). Th9 cell development requires a BATF-regulated transcriptional network. JOURNAL OF CLINICAL INVESTIGATION, 123(11), 4641-4653. doi:10.1172/JCI69489

Hua, L., Yao, S., Duy, P., Jiang, L., Wright, J., Sawant, D., . . . Sun, J. (2013). Cytokine-Dependent Induction of CD4⁺ T cells with Cytotoxic Potential during Influenza Virus Infection. JOURNAL OF VIROLOGY, 87(21), 11884-11893. doi:10.1128/JVI.01461-13

Sun, J., Dodd, H., Moser, E. K., Sharma, R., & Braciale, T. J. (2011). CD4⁺ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs. NATURE IMMUNOLOGY, 12(4), 327-U80. doi:10.1038/ni.1996