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Kenneth S. Tung

Kenneth S. Tung

Professor, Pathology

Primary Location
PO Box 800214
Primary Phone Number

Bio & Overview

Pathology

Academic Information

Department
Pathology
Academic Title
Professor

Primary Education

  • MBBS, Medicine, Melbourne University, Melbourne, Australia, 1959
  • Resident, Internal Medicine and Surgery, Melbourne University, Melbourne, Australia, 1962
  • Resident, Pathology, Cleveland Clinic, Cleveland, Ohio, 1968
  • Fellowship, Immunology, Scripps Clinic & Res. Fdn., La Jolla, CA, 1970

Other Appointments

  • Professor, Microbiology, Immunology, and Cancer Biology
  • Professor, MII
  • Professor, MOMD

Other Affiliations

  • Member, Immunology/Immunotherapy Program
  • Cardiovascular Research Center
  • Professor, BIMS

Research Interests

Pathology

Research Disciplines

  • Cardiovascular Biology
  • Experimental Pathology
  • Immunology

Research Opportunities

  • Cardiovascular Disease
  • Experimental Pathology
  • Immunology

Selected Publications

Harakal J, Rival C, Qiao H, Tung KS, Regulatory T Cells Control Th2-Dominant Murine Autoimmune Gastritis., 2016; Journal of immunology (Baltimore, Md. : 1950). 197(1) 27-41. PMID: 27259856 | PMCID: PMC4912916

Rival C, Setiady Y, Samy ET, Harakal J, Tung KS, The unique neonatal NK cells: a critical component required for neonatal autoimmune disease induction by maternal autoantibody., 2014; Frontiers in immunology. 5() 242. PMID: 24904590 | PMCID: PMC4035566

Coquery CM, Loo WM, Wade NS, Bederman AG, Tung KS, Lewis JE, Hess H, Erickson LD, BAFF regulates T follicular helper cells and affects accumulation and IFNγ production in autoimmunity., 2014; Arthritis & rheumatology (Hoboken, N.J.). () . PMID: 25385309 | PMCID: PMC4342294

Coquery CM, Wade NS, Loo WM, Kinchen JM, Cox KM, Jiang C, Tung KS, Erickson LD, Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice., 2014; PloS one. 9(7) e102284. PMID: 25010693 | PMCID: PMC4092127

Rival C, Wheeler K, Jeffrey S, Qiao H, Luu B, Tewalt EF, Engelhard VH, Tardif S, Hardy D, del Rio R, Teuscher C, Tung K, Regulatory T cells and vasectomy., 2013; Journal of reproductive immunology. 100(1) 66-75. PMID: 24080233 | PMCID: PMC3965253

Mauldin IS, Tung KS, Lorenz UM, The tyrosine phosphatase SHP-1 dampens murine Th17 development., 2012; Blood. 119(19) 4419-29. PMID: 22438258 | PMCID: PMC3362360

Tewalt EF, Cohen JN, Rouhani SJ, Guidi CJ, Qiao H, Fahl SP, Conaway MR, Bender TP, Tung KS, Vella AT, Adler AJ, Chen L, Engelhard VH, Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells., 2012; Blood. () . PMID: 22993390 | PMCID: PMC3520619

Wheeler K, Tardif S, Rival C, Luu B, Bui E, Del Rio R, Teuscher C, Sparwasser T, Hardy D, Tung KS, Regulatory T cells control tolerogenic versus autoimmune response to sperm in vasectomy., 2011; Proceedings of the National Academy of Sciences of the United States of America. 108(18) 7511-6. PMID: 21502500 | PMCID: PMC3088630

Jiang C, Loo WM, Greenley EJ, Tung KS, Erickson LD, B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus., 2011; Journal of immunology (Baltimore, Md. : 1950). 186(11) 6136-47. PMID: 21536804 | PMCID: PMC3181142

Ernst PB, Wiznerowicz EB, Feldman SH, Tung KS, Pathogenesis of gastritis in ileitis-prone SAMP1/Yit mice., 2011; The Keio journal of medicine. 60(2) 65-8. PMID: 21720202

Ernst PB, Erickson LD, Loo WM, Scott KG, Wiznerowicz EB, Brown CC, Torres-Velez FJ, Alam MS, Black SG, McDuffie M, Feldman SH, Wallace JL, McKnight GW, Padol IT, Hunt RH, Tung KS, Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice., 2011; American journal of physiology. Gastrointestinal and liver physiology. 302(1) G105-15. PMID: 21921286 | PMCID: PMC3345967

Carroll VA, Lundgren A, Wei H, Sainz S, Tung KS, Brown MG, Natural killer cells regulate murine cytomegalovirus-induced sialadenitis and salivary gland disease., 2011; Journal of virology. 86(4) 2132-42. PMID: 22156514 | PMCID: PMC3302420

Cohen JN, Guidi CJ, Tewalt EF, Qiao H, Rouhani SJ, Ruddell A, Farr AG, Tung KS, Engelhard VH, Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation., 2010; The Journal of experimental medicine. 207(4) 681-8. PMID: 20308365 | PMCID: PMC2856027

Case LK, Del Rio R, Bonney EA, Zachary JF, Blankenhorn EP, Tung KS, Teuscher C, The postnatal maternal environment affects autoimmune disease susceptibility in A/J mice., 2009; Cellular immunology. 260(2) 119-27. PMID: 19914609 | PMCID: PMC2795069

Guth A, Detanico T, Smith D, Tung KS, Bonorino C, Wysocki LJ, Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3., 2009; Lupus. 18(4) 299-308. PMID: 19276297 | PMCID: PMC2892212

Wheeler KM, Samy ET, Tung KS, Cutting edge: normal regional lymph node enrichment of antigen-specific regulatory T cells with autoimmune disease-suppressive capacity., 2009; Journal of immunology (Baltimore, Md. : 1950). 183(12) 7635-8. PMID: 19923458 | PMCID: PMC2872190

Chavali AK, Gianchandani EP, Tung KS, Lawrence MB, Peirce SM, Papin JA, Characterizing emergent properties of immunological systems with multi-cellular rule-based computational modeling., 2008; Trends in immunology. 29(12) 589-99. PMID: 18964301

Samy ET, Wheeler KM, Roper RJ, Teuscher C, Tung KS, Cutting edge: Autoimmune disease in day 3 thymectomized mice is actively controlled by endogenous disease-specific regulatory T cells., 2008; Journal of immunology (Baltimore, Md. : 1950). 180(7) 4366-70. PMID: 18354156

Samy ET, Setiady YY, Ohno K, Pramoonjago P, Sharp C, Tung KS, The role of physiological self-antigen in the acquisition and maintenance of regulatory T-cell function., 2006; Immunological reviews. 212() 170-84. PMID: 16903914