Matthew Wolf

Wolf, Matthew J

Primary Appointment

Associate Professor, Medicine: Cardiovascular Medicine


  • Fellowship, Cardiology, Duke University School of Medicine, Durham, NC
  • Residency, Internal Medicine, Duke University School of Medicine, Durham, NC
  • MD, , Washington University School of Medicine
  • PhD, Biochemistry, Washington University School of Medicine

Contact Information

Heart and Vascular Center Northridge
2nd floor, 1215 Lee St.
Charlottesville, VA 22908
Telephone: 434-243-1000
Fax: 434-244-7551

Research Disciplines

Cardiovascular Biology, Genetics, Physiology

Research Interests

Identification of genes and pathways that cause or modify cardiac hypertrophy and heart failure.

Research Description

Our mission is to understand how signaling molecules mediate cardiomyocyte growth, hypertrophy, and heart failure. We use novel approaches based on fruit fly genetics to identify genes that cause or modify cardiomyopathies and translate these findings using mammalian cell-based systems and transgenic mice. Our multidisciplinary approach employs state-of-the-art Optical Coherence Tomography, confocal microscopy, molecular and cell biology, proteomics, and physiology to understand cardiovascular disease.

Selected Publications