Tsai, Ming-Feng
Primary Appointment
Associate Professor, Molecular Physiology and Biological Physics
Education
- B.S., National Yang-Ming University, Taiwan
- Ph.D., University of Missouri
Contact Information
Email: vmf6uw@virginia.edu
Website: http://www.tsaislab.org/
Research Disciplines
Biochemistry, Biophysics, Cardiovascular Biology, Metabolism, Molecular and Cellular Physiology, Molecular Biology, Molecular Pharmacology, Molecular Physiology and Biological Physics, Physiology, Structural Biology, Translational Science
Research Interests
Membrane-transport physiology and biophysics
Research Description
Our research focuses on the molecular mechanisms of mitochondrial calcium transport and signaling. We aim to understand how these mitochondrial processes contribute to cardiovascular and neuronal physiology, as well as their involvement in related diseases. To tackle these questions, we employ a multidisciplinary approach that integrates membrane biochemistry and biophysics, electrophysiology, cryo-electron microscopy, cell biology, and animal models. In parallel, we are actively engaged in identifying pharmacological compounds that target mitochondrial proteins, with the goal of developing novel strategies for disease treatment.