6/17/2025
Research in the area of organic chemistry is focused on the synthesis of bleomycin group antibiotics; members of this family are used clinically as antitumor agents. The total synthesis of…
6/17/2025
Living cells and tissues adapt to their environment by altering structure, gene and protein expression, and biochemical functions. For example, endothelial cells lining the artery wall at the blood tissue…
6/17/2025
My laboratory conducts basic science research on the involvement of growth factors in cancer. Although dysregulation of growth factor systems has been implicated in a variety of cancers, our primary…
6/17/2025
Human development, immunity, wound healing, fertility, and nutrient uptake all depend upon the ability of cells to change shape. Acquisition of an asymmetric or polarized morphology by a cell is…
6/17/2025
Bioreactor Related ResearchThere are currently two ongoing bioreactor-related research programs in our laboratory funded by the National Science Foundation (NSF) and National Aeronautics and Space Administration (NASA). A multidisciplinary approach…
6/17/2025
I am interested in understanding the molecular mechanisms that control the generation of different neuronal types along the anterior-posterior (A-P) axis of the spinal cord, using motor neurons as a…
6/17/2025
Genomic analysis of primary human cancer specimens for global genetic and gene expression alterations. Development of model systems to validate biological roles of candidate genes. Translation of experimental findings to…
6/17/2025
Identification of Factors and Mechanisms that Regulate the Stability of Late Stage Atherosclerotic Lesions and the Probability of Thromboembolic Events Including a Heart Attack or StrokeAtherothrombosis, resulting from rupture or…
6/17/2025
Systems analysis has become a requirement for making sense of high-throughput data and for characterizing properties of biological networks. In order to extend these recent developments to medical applications, there…
6/17/2025
Director of Graduate Studies for Microbiology, Immunology and Cancer BiologyPlease contact Dr. Pemberton for any information or guidance regarding our graduate program. Associate Director of Education, UVA Comprehensive Cancer CenterDr…
