6/17/2025
My laboratory develops and applies computational statistics methods to functional genomic data with a focus on epigenetic data. Epigenetics is the study of heritable phenotypic traits not coded in the…
6/17/2025
Membranes and membrane proteins participate in some of the most important and interesting cellular processes. Energy transduction, cell signaling, membrane excitability, secretion and immune recognition are examples of a few…
6/17/2025
The longstanding interest of my laboratory is on the regulation of membrane trafficking in the secretory and endocytic pathways. A new direction that is a major focus of our research…
6/17/2025
Project 1. Role of the embryonic stem cell pluripotency factor OCT4 in the regulation of phenotypic transition of vascular cells after vascular injury, under the contexts of hyperlipidemia and cancer. Recently,…
6/17/2025
Membrane proteins facilitate the transfer of information across lipid bilayers, comprise approximately 25% of a typical proteome, and represent over half of all drug targets. The membrane proteins that mediate…
6/17/2025
Although I still determine structures using X-ray crystallography, I am currently primarily involved in the development of a new generation of Laboratory Information Management System (LIMS) to track experimental procedures…
6/17/2025
The design of self-assembling nanomaterials stands as one of the great challenges in modern molecular science. The DuBay group employs theoretical and computational tools to address this challenge through investigations…
6/17/2025
Our research is focused on the structure and function of macromolecular assemblies, using the techniques of electron cryo-microscopy and three-dimensional reconstruction. Historically, we have been working in two different areas:…
6/17/2025
Our research focuses on the application of chemical engineering principles to problems in microbial ecology. The aim is to develop a fundamental understanding of mechanisms underlying microbial behavior which will…
