6/17/2025
My laboratory is using the fruit fly, Drosophila melanogaster, as a model system for studying the molecular genetics of responsiveness to cocaine and other drugs of abuse. We have shown…
6/17/2025
1) Seizures as brain explorers: A few thousand neurons acting together can generate a seizure, but it travels far from its origin, generating convulsive and dystonic movements, triggering and erasing…
6/17/2025
The goal of our research is to learn the cellular, molecular and biomechanical mechanisms underlying morphogenetic movements during embryogenesis. One of the fundamental problems in developmental biology is determining what…
6/17/2025
6/17/2025
The long-term goal of our research program is to elucidate the roles of peripheral and central glia and glial-glial interactions during nervous system development, maintenance and disease/injury. Using Danio rerio…
6/17/2025
Neural regeneration within the central nervous system (CNS) is a critical unmet challenge as CNS disorders continue to be the leading cause of disability nationwide. Engineers can provide a unique…
6/17/2025
I have been interested in understanding the regulation and misregulation of retinal structures and functions during normal development and in diseased conditions since my PhD study. I started my own…
6/17/2025
1. Wnt and PCP signaling in mechanosensory hair cell polarity. The actin-based hair bundle atop sensory hair cells is the mechanotransduction organelle essential for hearing and balance. A majority of sensorineural…
6/17/2025
Our research investigates the biology of the lipid mediator, sphingosine 1-phosphate (S1P). S1P concentration gradients are known to influence immune cell positioning. Indeed, S1P type 1 receptor agonist drugs are…
6/17/2025
My laboratory uses behavioral, pharmacological, and molecular techniques to delineate the neurobiological basis of addiction. We are particularly interested in determining the biological basis of sex differences in vulnerability to…
